Search Results - "To, Ho"

Central Role of Oxidative Stress in Age-Related Macular Degeneration: Evidence from a Review of the Molecular Mechanisms and Animal Models by Tse, Dennis Yan-yin, Lam, Tim T., To, Chi-ho, Abokyi, Samuel

“…Age-related macular degeneration (AMD) is a common cause of visual impairment in the elderly. There are very limited therapeutic options for AMD with the…”
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Baicalein, Baicalin, and Wogonin: Protective Effects against Ischemia-Induced Neurodegeneration in the Brain and Retina by Pan, Li, Cho, Kin-Sang, Yi, Irvin, To, Chi-Ho, Chen, Dong Feng, Do, Chi-Wai

“…Ischemia is a common pathological condition present in many neurodegenerative diseases, including ischemic stroke, retinal vascular occlusion, diabetic…”
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Retinal Proteomic Analysis in a Mouse Model of Endotoxin-Induced Uveitis Using Data-Independent Acquisition-Based Mass Spectrometry by Zhang, Jing, Wu, Jiangmei, Lu, Daqian, To, Chi-Ho, Lam, Thomas Chuen, Lin, Bin

“…Uveitis is a group of sight-threatening ocular inflammatory diseases, potentially leading to permanent vision loss in patients. However, it remains largely…”
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Identification of Potential Growth-Related Proteins in Chick Vitreous during Emmetropization Using SWATH-MS and Targeted-Based Proteomics (MRMHR) by Cheung, Jimmy Ka-Wai, Li, King-Kit, Zhou, Lei, To, Chi-Ho, Lam, Thomas Chuen

“…The vitreous humor (VH) is a transparent gelatin-like substance that occupies two-thirds of the eyeball and undergoes the most significant changes during eye…”
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SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina by Bian, Jingfang, Sze, Ying-Hon, Tse, Dennis Yan-Yin, To, Chi-Ho, McFadden, Sally A, Lam, Carly Siu-Yin, Li, King-Kit, Lam, Thomas Chuen

“…Most of the previous myopic animal studies employed a single-candidate approach and lower resolution proteomics approaches that were difficult to detect minor…”
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Thrombospondin‐1 mediates Rho‐kinase inhibitor‐induced increase in outflow‐facility by Shan, Sze‐Wan, Do, Chi‐Wai, Lam, Thomas Chuen, Li, Hoi‐Lam, Stamer, W. Daniel, To, Chi‐Ho

“…Rho‐kinase (ROCK) inhibitors, a novel class of anti‐glaucoma agents, act by increasing the aqueous humor outflow through the conventional trabecular meshwork…”
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Differences in the corneal biomechanical changes after SMILE and LASIK by Wang, Danyang, Liu, Manli, Chen, Yile, Zhang, Xiaoying, Xu, Yangtao, Wang, Jianchao, To, Chi-Ho, Liu, Quan

“…To compare the corneal biomechanical properties before and after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK in different…”
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Reconsidering Social Cohesion: Developing a Definition and Analytical Framework for Empirical Research by Chan, Joseph, To, Ho-Pong, Chan, Elaine

“…Despite its growing currency in academic and policy circles, social cohesion is a term in need of a clearer and more rigorous definition. This article provides…”
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Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration by Kwong, Jacky M K, Caprioli, Joseph, Lee, Joanne C Y, Song, Yifan, Yu, Feng-Juan, Bian, Jingfang, Sze, Ying-Hon, Li, King-Kit, Do, Chi-Wai, To, Chi-Ho, Lam, Thomas Chuen

“…To explore the temporal profile of retinal proteomes specific to primary and secondary retinal ganglion cell (RGC) loss. Unilateral partial optic nerve…”
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Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells by Abokyi, Samuel, Shan, Sze-Wan, Lam, Christie Hang-I, Catral, Kirk Patrick, Pan, Feng, Chan, Henry Ho-Lung, To, Chi-Ho, Tse, Dennis Yan-Yin

“…In age-related macular degeneration (AMD), hydroquinone (HQ)-induced oxidative damage in retinal pigment epithelium (RPE) is believed to be an early event…”
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Myopia: mechanisms, manifestations and management by Logan, Nicola, Guggenheim, Jez, To, Chi‐ho

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Mechanistic Effects of Baicalein on Aqueous Humor Drainage and Intraocular Pressure by Li, Hoi-Lam, Shan, Sze Wan, Stamer, W Daniel, Li, King-Kit, Chan, Henry Ho-Lung, Civan, Mortimer M, To, Chi-Ho, Lam, Thomas Chuen, Do, Chi-Wai

“…Elevated intraocular pressure (IOP) is a major risk factor for glaucoma that results from impeded fluid drainage. The increase in outflow resistance is caused…”
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Regulation of Aqueous Humor Secretion by Melatonin in Porcine Ciliary Epithelium by Li, Ka-Lok, Shan, Sze-Wan, Lin, Fang-Yu, Ling, Choi-Ying, Wong, Nga-Wai, Li, Hoi-Lam, Han, Wei, To, Chi-Ho, Do, Chi-Wai

“…Secretion of melatonin, a natural hormone whose receptors are present in the ciliary epithelium, displays diurnal variation in the aqueous humor (AH),…”
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Characterization of an atypical Actinobacillus pleuropneumoniae serovar 2 isolate with a rough-type lipopolysaccharide by TO, Ho, AKAIKE, Yuta, KON, Michiha, KOIKE, Fumiko, SHIBUYA, Kazumoto, SASAKAWA, Chihiro, NAGAI, Shinya

“…We describe phenotypic and genetic characterization of an atypical Japanese Actinobacillus pleuropneumoniae isolate OT761. Nucleotide sequence analysis…”
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Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells by Chan, Henry Ho-lung, To, Chi-ho, Shan, Sze wan, Abokyi, Samuel, Tse, Dennis Yan-yin

“…Trehalose is a natural dietary molecule that has shown antiaging and neuroprotective effects in several animal models of neurodegenerative diseases. The role…”
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Multiple scan averaging to yield accurate quantitative analysis of optical coherence tomography angiograms by Khan, Hafi M., Gentle, Alex, Armitage, James A., To, Chi-ho, Lam, Andrew K. C.

“…Optical coherence tomography angiography (OCTA) is widely used in ophthalmic practice. Most OCTA studies based their findings on a single OCTA measurement. We…”
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Development pattern of ocular biometric parameters and refractive error in young Chinese adults: a longitudinal study of first-year university students by Bai, Xue, Jin, Nan, Wang, Qingxin, Ge, Yicheng, Du, Bei, Wang, Di, Su, Qiang, Wang, Biying, To, Chi-Ho, Wei, Ruihua

“…The increase in the prevalence of myopia has become a matter of serious public health concern, and few studies to date have examined the ocular biometric…”
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Proposal of a subtype of serovar 4, K4b:O3, of Actinobacillus pleuropneumoniae based on serological and genotypic analysis by To, Ho, Kon, Michiha, Koike, Fumiko, Shibuya, Kazumoto, Nagai, Shinya, Gottschalk, Marcelo, Frey, Joachim, Sasakawa, Chihiro

“…•Identification of A. pleuropneumoniae subtype K4b of serovar 4 type II capsule locus.•Subtype K4b isolate is biovar 1, and harbors apxIICA, apxIBD and apxIVA…”
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The city-wide full-scale interactive application of sewage surveillance programme for assisting real-time COVID-19 pandemic control – A case study in Hong Kong by Ng, Wai-yin, Thoe, Wai, Yang, Rong, Cheung, Wai-ping, Chen, Che-kong, To, King-ho, Pak, Kan-ming, Leung, Hon-wan, Lai, Wai-kwan, Wong, Tsz-kin, Lau, Tat-kwong, Au, Ka-wing, Xu, Xiao-qing, Zheng, Xia-wan, Deng, Yu, Lau, Yan-kin, To, Chi-kai, Peiris, Malik, Leung, Gabriel M., Zhang, Tong, Yang, Min, An, Wei, Chen, Wenxiu, Wang, Chen, Chui, Ho-kwong

“…The paper discusses the implementation of Hong Kong's tailor-made sewage surveillance programme led by the Government, which has demonstrated how an efficient…”
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Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders by Xiao, Jing-Ru, Do, Chi-Wai, To, Chi-Ho

“…Ocular diseases such as cataract, glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy are the leading causes of blindness. The elderly…”
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