Search Results - "Tkachev, Victor S"

Next-Generation Grade and Survival Expression Biomarkers of Human Gliomas Based on Algorithmically Reconstructed Molecular Pathways by Zolotovskaia, Marianna A, Kovalenko, Max A, Tkachev, Victor S, Simonov, Alexander M, Sorokin, Maxim I, Kim, Ella, Kuzmin, Denis V, Karademir-Yilmaz, Betul, Buzdin, Anton A

“…In gliomas, expression of certain marker genes is strongly associated with survival and tumor type and often exceeds histological assessments. Using a human…”
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Disparity between Inter-Patient Molecular Heterogeneity and Repertoires of Target Drugs Used for Different Types of Cancer in Clinical Oncology by Zolotovskaia, Marianna A, Sorokin, Maxim I, Petrov, Ivan V, Poddubskaya, Elena V, Moiseev, Alexey A, Sekacheva, Marina I, Borisov, Nicolas M, Tkachev, Victor S, Garazha, Andrew V, Kaprin, Andrey D, Shegay, Peter V, Giese, Alf, Kim, Ella, Roumiantsev, Sergey A, Buzdin, Anton A

“…Inter-patient molecular heterogeneity is the major declared driver of an expanding variety of anticancer drugs and personalizing their prescriptions. Here, we…”
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OncoboxPD: human 51 672 molecular pathways database with tools for activity calculating and visualization by Zolotovskaia, Marianna A., Tkachev, Victor S., Guryanova, Anastasia A., Simonov, Alexander M., Raevskiy, Mikhail M., Efimov, Victor V., Wang, Ye, Sekacheva, Marina I., Garazha, Andrew V., Borisov, Nicolas M., Kuzmin, Denis V., Sorokin, Maxim I., Buzdin, Anton A.

“…OncoboxPD (Oncobox pathway databank) available at https://open.oncobox.com is the collection of 51 672 uniformly processed human molecular pathways…”
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Pan-cancer antagonistic inhibition pattern of ATM-driven G2/M checkpoint pathway vs other DNA repair pathways by Zolotovskaia, Marianna A., Modestov, Alexander A., Suntsova, Maria V., Rachkova, Anastasia A., Koroleva, Elena V., Poddubskaya, Elena V., Sekacheva, Marina I., Tkachev, Victor S., Garazha, Andrew V., Glusker, Alexander A., Seryakov, Aleksander P., Vladimirova, Uliana S., Rumiantsev, Pavel O., Moisseev, Aleksey A., Zharkov, Dmitry O., Kuzmin, Denis V., Zhao, Xiaowen, Prassolov, Vladimir S., Shegay, Petr V., Li, Xinmin, Steinbichler, Teresa B., Kim, Ella, Sorokin, Maxim I., Wang, Ye, Buzdin, Anton A.

“…DNA repair mechanisms keep genome integrity and limit tumor-associated alterations and heterogeneity, but on the other hand they promote tumor survival after…”
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Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer by Zolotovskaia, Marianna A, Tkachev, Victor S, Seryakov, Alexander P, Kuzmin, Denis V, Kamashev, Dmitry E, Sorokin, Maxim I, Roumiantsev, Sergey A, Buzdin, Anton A

“…Carcinogenesis is linked with massive changes in regulation of gene networks. We used high throughput mutation and gene expression data to interrogate…”
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Large-scale assessment of pros and cons of autopsy-derived or tumor-matched tissues as the norms for gene expression analysis in cancers by Sorokin, Maksim, Buzdin, Anton A., Guryanova, Anastasia, Efimov, Victor, Suntsova, Maria V., Zolotovskaia, Marianna A., Koroleva, Elena V., Sekacheva, Marina I., Tkachev, Victor S., Garazha, Andrew, Kremenchutckaya, Kristina, Drobyshev, Aleksey, Seryakov, Aleksander, Gudkov, Alexander, Alekseenko, Irina V., Rakitina, Olga, Kostina, Maria B., Vladimirova, Uliana, Moisseev, Aleksey, Bulgin, Dmitry, Radomskaya, Elena, Shestakov, Viktor, Baklaushev, Vladimir P., Prassolov, Vladimir, Shegay, Petr V., Li, Xinmin, Poddubskaya, Elena V., Gaifullin, Nurshat

“…Normal tissues are essential for studying disease-specific differential gene expression. However, healthy human controls are typically available only in…”
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