Search Results - "Tjernberg, L"

Transmissible amyloid by Tjernberg, L.O., Rising, A., Johansson, J., Jaudzems, K., Westermark, P.

“…There are around 30 human diseases associated with protein misfolding and amyloid formation, each one caused by a certain protein or peptide. Many of these…”
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Improved cost–benefit analysis for market-based transmission planning, a European perspective by Papaemmanouil, A., Bertling Tjernberg, L., Tuan, L.A., Andersson, G.

“…This paper addresses the problem of transmission planning in interconnected power systems under the uncertainty of future generation parks and fast varying…”
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The N‐glycan profile in cortex and hippocampus is altered in Alzheimer disease by Gaunitz, Stefan, Tjernberg, Lars O., Schedin‐Weiss, Sophia

“…Protein glycosylation is crucial for the central nervous system and brain functions, including processes that are defective in Alzheimer disease (AD) such as…”
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Glycan biomarkers for Alzheimer disease correlate with T‐tau and P‐tau in cerebrospinal fluid in subjective cognitive impairment by Schedin‐Weiss, Sophia, Gaunitz, Stefan, Sui, Ping, Chen, Qiushi, Haslam, Stuart M., Blennow, Kaj, Winblad, Bengt, Dell, Anne, Tjernberg, Lars O.

“…Alzheimer disease (AD) is a devastating disease and a global health problem, and current treatments are only symptomatic. A wealth of clinical studies support…”
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Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide by Johansson, J, Weaver, T E, Tjernberg, L O

“…The formation of amyloid fibrils is associated with several devastating diseases in humans and animals, including e.g. Alzheimer's disease (AD) and the…”
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Relative Abundance of Alzheimer Aβ Amyloid Peptide Variants in Alzheimer Disease and Normal Aging by Näslund, Jan, Schierhorn, Angelika, Hellman, Ulf, Lannfelt, Lars, Roses, Allen D., Tjernberg, Lars O., Silberring, Jerzy, Gandy, Samuel E., Winblad, Bengt, gard, Paul Green, Nordstedt, Christer, Terenius, Lars

“…The Alzheimer Aβ amyloid peptide (Aβ) is the principal proteinaceous component of amyloid associated with Alzheimer disease (AD). We have determined the…”
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A molecular model of Alzheimer amyloid beta-peptide fibril formation by Tjernberg, L O, Callaway, D J, Tjernberg, A, Hahne, S, Lilliehöök, C, Terenius, L, Thyberg, J, Nordstedt, C

“…Polymerization of the amyloid beta (Abeta) peptide into protease-resistant fibrils is a significant step in the pathogenesis of Alzheimer's disease. It has not…”
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Arrest of beta-amyloid fibril formation by a pentapeptide ligand by Tjernberg, L O, Näslund, J, Lindqvist, F, Johansson, J, Karlström, A R, Thyberg, J, Terenius, L, Nordstedt, C

“…Polymerization of amyloid beta-peptide (Abeta) into amyloid fibrils is a critical step in the pathogenesis of Alzheimer's disease. Here, we show that peptides…”
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Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid ?-peptide by Johansson, J., Weaver, T. E., Tjernberg, L. O.

“…The formation of amyloid fibrils is associated with several devastating diseases in humans and animals, including e.g. Alzheimer's disease (AD) and the…”
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Medin: An Integral Fragment of Aortic Smooth Muscle Cell-Produced Lactadherin Forms the Most Common Human Amyloid by Häggqvist, Bo, Näslund, Jan, Sletten, Knut, Westermark, Gunilla T., Mucchiano, Gerd, Tjernberg, Lars O., Nordstedt, Christer, Engström, Ulla, Westermark, Per

“…Aortic medial amyloid is a form of localized amyloid that occurs in virtually all individuals older than 60 years. The importance and impact of the amyloid…”
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Controlling amyloid beta-peptide fibril formation with protease-stable ligands by Tjernberg, L O, Lilliehöök, C, Callaway, D J, Näslund, J, Hahne, S, Thyberg, J, Terenius, L, Nordstedt, C

“…We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide…”
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Short Term Load Forecasting of Electrical Power Distribution System Using Enhanced Deep Neural Networks (DNNs) by Tsegaye, Shewit, Sanjeevikumar, P., Bertling Tjernberg, L., Fante, Kinde A.

“…The rationale for using enhanced Deep Neural Networks (DNNs) in the power distribution system for short-term load forecasting originates from a thorough…”
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The Alzheimer A beta peptide develops protease resistance in association with its polymerization into fibrils by Nordstedt, C, Näslund, J, Tjernberg, L O, Karlström, A R, Thyberg, J, Terenius, L

“…An intriguing property of the polypeptide constituents of amyloid is that they apparently can escape the proteolytic mechanisms that normally catalyze turnover…”
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Highly Sensitive FRET-FCS Detects Amyloid β‑Peptide Oligomers in Solution at Physiological Concentrations by Wennmalm, Stefan, Chmyrov, Volodymyr, Widengren, Jerker, Tjernberg, Lars

“…Oligomers formed by the amyloid β-peptide (Aβ) are pathogens in Alzheimer’s disease. Increased knowledge on the oligomerization process is crucial for…”
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Defeating Alzheimer's disease and other dementias: a priority for European science and society by Winblad, Bengt, Prof, Amouyel, Philippe, Prof, Andrieu, Sandrine, Prof, Ballard, Clive, Prof, Brayne, Carol, Prof, Brodaty, Henry, Prof, Cedazo-Minguez, Angel, PhD, Dubois, Bruno, Prof, Edvardsson, David, Prof, Feldman, Howard, Prof, Fratiglioni, Laura, Prof, Frisoni, Giovanni B, Prof, Gauthier, Serge, Prof, Georges, Jean, BA, Graff, Caroline, Prof, Iqbal, Khalid, Prof, Jessen, Frank, Prof, Johansson, Gunilla, Jönsson, Linus, MD, Kivipelto, Miia, Prof, Knapp, Martin, Prof, Mangialasche, Francesca, MD, Melis, René, PhD, Nordberg, Agneta, Prof, Rikkert, Marcel Olde, Prof, Qiu, Chengxuan, MD, Sakmar, Thomas P, Prof, Scheltens, Philip, Prof, Schneider, Lon S, Prof, Sperling, Reisa, Prof, Tjernberg, Lars O, PhD, Waldemar, Gunhild, Prof, Wimo, Anders, Prof, Zetterberg, Henrik, Prof

“…[...]a substantial increase in long-term funding for multidisciplinary research programmes is absolutely essential to reduce the burden of individual suffering…”
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Binding of amyloid β-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer’s disease by Oppermann, Udo C.T., Salim, Samina, Tjernberg, Lars O., Terenius, Lars, Jörnvall, Hans

“…The intracellular amyloid β-peptide (Aβ) binding protein, ERAB, a member of the short-chain dehydrogenase/reductase (SDR) family, is known to mediate apoptosis…”
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The impact of the COVID-19 pandemic on neurosurgery in the elderly population in Sweden by Axenhus, Michael, Schedin-Weiss, Sophia, Tjernberg, Lars, Winblad, Bengt

“…The COVID-19 pandemic prompted a refocus of health care resources to acute care which has impacted on the capacity of healthcare systems to conduct…”
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Optimizing Wind Power Hosting Capacity of Distribution Systems Using Cost Benefit Analysis by Nursebo, Shemsedin, Peiyuan Chen, Carlson, Ola, Tjernberg, L. Bertling

“…The penetration of wind power into the electricity grid is growing significantly. A significant portion of this wind power is being installed in distribution…”
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Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain by Näslund, Jan, Thyberg, Johan, Tjernberg, Lars O., Wernstedt, Christer, Karlström, Anders R., Bogdanovic, Nenad, Gandy, Samuel E., Lannfelt, Lars, Terenius, Lars, Nordstedt, Christer

“…Genetic evidence suggests a role for apolipoprotein E (apoE) in Alzheimer's disease (AD) amyloidogenesis. Here, amyloid-associated apoE from 32 AD patients was…”
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DEAD Box Helicase 24 Is Increased in the Brain in Alzheimer's Disease and App N-LF Mice and Influences Presymptomatic Pathology by Axenhus, Michael, Doeswijk, Tosca, Nilsson, Per, Matton, Anna, Winblad, Bengt, Tjernberg, Lars, Schedin-Weiss, Sophia

“…At the time of diagnosis, Alzheimer's disease (AD) patients already suffer from significant neuronal loss. The identification of proteins that influence…”
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