Search Results - "Tiwari, Ajit"
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Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
Published in Nature communications (25-01-2019)“…The intracellular ciliogenesis pathway requires membrane trafficking, fusion, and reorganization. Here, we demonstrate in human cells and zebrafish that the…”
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Rhizoctonia solani Kühn Pathophysiology: Status and Prospects of Sheath Blight Disease Management in Rice
Published in Frontiers in plant science (03-05-2022)“…Sheath blight caused by necrotrophic fungus Kühn is one of the most serious diseases of rice. Use of high yielding semi dwarf cultivars with dense planting and…”
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Cholera Toxin as a Probe for Membrane Biology
Published in Toxins (03-08-2021)“…Cholera toxin B-subunit (CTxB) has emerged as one of the most widely utilized tools in membrane biology and biophysics. CTxB is a homopentameric stable protein…”
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Publisher Correction: Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
Published in Nature communications (19-02-2019)“…In the original version of this Article, the fifth sentence of the abstract incorrectly read ‘Remarkably, we show that PACSIN1 and EHD1 assemble membrane…”
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Endothelial Cell Migration on Fibronectin Is Regulated by Syntaxin 6-mediated α5β1 Integrin Recycling
Published in The Journal of biological chemistry (21-10-2011)“…The α5β1 integrin heterodimer regulates many processes that contribute to embryonic development and angiogenesis, in both physiological and pathological…”
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Microtubule Motors Power Plasma Membrane Tubulation in Clathrin‐Independent Endocytosis
Published in Traffic (Copenhagen, Denmark) (01-06-2015)“…How the plasma membrane is bent to accommodate clathrin‐independent endocytosis remains uncertain. Recent studies suggest Shiga and cholera toxin induce…”
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Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase
Published in Biochemical journal (15-06-2012)“…IL (interleukin)-6, an established growth factor for multiple myeloma cells, induces myeloma therapy resistance, but the resistance mechanisms remain unclear…”
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Secretion of soluble vascular endothelial growth factor receptor 1 (sVEGFR1/sFlt1) requires Arf1, Arf6, and Rab11 GTPases
Published in PloS one (04-09-2012)“…The soluble form of vascular endothelial growth factor receptor 1 (sVEGFR-1/sFlt1) is generated by alternative splicing of the FLT1 gene. Secretion of sFlt1…”
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Assembly and Turnover of Caveolae: What Do We Really Know?
Published in Frontiers in cell and developmental biology (27-06-2016)“…In addition to containing highly dynamic nanoscale domains, the plasma membranes of many cell types are decorated with caveolae, flask-shaped domains enriched…”
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High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts
Published in ACS central science (23-03-2022)“…Plasma membrane organization profoundly impacts cellular functionality. A well-known mechanism underlying this organization is through nanoscopic clustering of…”
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Syntaxin 16 regulates lumen formation during epithelial morphogenesis
Published in PloS one (23-04-2013)“…The formation and maintenance of cell-cell junctions, both under physiological and pathological conditions, requires the targeting and trafficking of…”
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Identification of proteins secreted by malaria parasite into erythrocyte using SVM and PSSM profiles
Published in BMC bioinformatics (16-04-2008)“…Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for…”
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Correction: Secretion of Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1/sFlt1) Requires Arf1, Arf6, and Rab11 GTPases
Published in PloS one (20-11-2012)“…There was an error in the funding statement. Citation: Jung J-J, Tiwari A, Inamdar SM, Thomas CP, Goel A, Choudhury A (2012) Correction: Secretion of Soluble…”
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The C99 domain of the amyloid precursor protein resides in the disordered membrane phase
Published in The Journal of biological chemistry (01-01-2021)“…Processing of the amyloid precursor protein (APP) via the amyloidogenic pathway is associated with the etiology of Alzheimer’s disease. The cleavage of APP by…”
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Tagging Strategies Strongly Affect the Fate of Overexpressed Caveolin‐1
Published in Traffic (Copenhagen, Denmark) (01-04-2015)“…Caveolin‐1 (Cav1) is the primary scaffolding protein of caveolae, flask‐shaped invaginations of the plasma membrane thought to function in endocytosis,…”
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Use of Giant Plasma Membrane Vesicles (GPMV) to Examine the Lo/Ld Phase Preference of the C99 Domain of the Amyloid Precursor Protein
Published in Biophysical journal (07-02-2020)Get full text
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APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway
Published in Developmental cell (12-03-2018)“…Adenomatous polyposis coli (APC) mutations cause Wnt pathway activation in human cancers. Current models for APC action emphasize its role in promoting…”
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Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6
Published in Blood (27-01-2011)“…Vascular endothelial growth factor receptor 2 (VEGFR2) plays a key role in physiologic and pathologic angiogenesis. Plasma membrane (PM) levels of VEGFR2 are…”
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High Content Imaging to Identify Modulators of Membrane Phase Behavior
Published in Biophysical journal (07-02-2020)Get full text
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The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling
Published in American journal of physiology. Heart and circulatory physiology (01-03-2013)“…Vascular endothelial growth factor receptor-2 (VEGFR2) is a receptor tyrosine kinase that is expressed in endothelial cells and regulates angiogenic signal…”
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