Search Results - "Titulaer, M. J"

Antibody Therapies in Autoimmune Encephalitis by Smets, I., Titulaer, M. J.

“…Autoimmune encephalitis (AE) comprises a heterogeneous group of disorders in which the host immune system targets self-antigens expressed in the central…”
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Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome by LANCASTER, E, MARTINEZ-HERNANDEZ, E, WONG, S, XU, J, CONTRACTOR, A, BALICE-GORDON, R, DALMAU, J, TITULAER, M. J, BOULOS, M, WEAVER, S, ANTOINE, J.-C, LIEBERS, E, KORNBLUM, C, BIEN, C. G, HONNORAT, J

“…To report the metabotropic glutamate receptor 5 (mGluR5) as the autoantigen of antibodies from 2 patients with Hodgkin lymphoma (HL) and limbic encephalopathy…”
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Screening for tumours in paraneoplastic syndromes: report of an EFNS Task Force by Titulaer, M. J., Soffietti, R., Dalmau, J., Gilhus, N. E., Giometto, B., Graus, F., Grisold, W., Honnorat, J., Sillevis Smitt, P. A. E., Tanasescu, R., Vedeler, C. A., Voltz, R., Verschuuren, J. J. G. M.

“…Background:  Paraneoplastic neurological syndromes (PNS) almost invariably predate detection of the malignancy. Screening for tumours is important in PNS as…”
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Efficacy of 3,4-Diaminopyridine and Pyridostigmine in the Treatment of Lambert-Eaton Myasthenic Syndrome: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study by Wirtz, PW, Verschuuren, JJ, Dijk, JG, Kam, ML, Schoemaker, RC, Hasselt, JGC, Titulaer, MJ, Tjaden, UR, Hartigh, J, Gerven, JMA

“…3,4‐Diaminopyridine and pyridostigmine are widely used to treat Lambert–Eaton myasthenic syndrome (LEMS), either alone or in combination. 3,4‐Diaminopyridine…”
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Intracranial actinomycosis of odontogenic origin masquerading as auto-immune orbital myositis: a fatal case and review of the literature by Hötte, G J, Koudstaal, M J, Verdijk, R M, Titulaer, M J, Claes, J F H M, Strabbing, E M, van der Lugt, A, Paridaens, D

“…Actinomycetes can rarely cause intracranial infection and may cause a variety of complications. We describe a fatal case of intracranial and intra-orbital…”
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Physical activity and the association with sporadic ALS by VELDINK, J. H, KALMIJN, S, GROENEVELD, G. J, TITULAER, M. J, WOKKE, J. H. J, VAN DEN BERG, L. H

“…To assess whether lifetime physical activity during work and leisure time is associated with an increased risk of developing ALS and to determine the…”
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Molecular and cellular mechanisms underlying anti-neuronal antibody mediated disorders of the central nervous system by van Coevorden-Hameete, M.H, de Graaff, E, Titulaer, M.J, Hoogenraad, C.C, Sillevis Smitt, P.A.E

“…Abstract Over the last decade multiple autoantigens located on the plasma membrane of neurons have been identified. Neuronal surface antigens include molecules…”
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The Lambert–Eaton myasthenic syndrome 1988–2008: A clinical picture in 97 patients by Titulaer, M.J, Wirtz, P.W, Kuks, J.B.M, Schelhaas, H.J, van der Kooi, A.J, Faber, C.G, van der Pol, W.L, de Visser, M, Sillevis Smitt, P.A.E, Verschuuren, J.J.G.M

“…Abstract Background Neuromuscular symptoms in patients with Lambert–Eaton myasthenic syndrome (LEMS) and a small cell lung cancer (SCLC) develop more rapidly…”
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Antibodies to NMDA receptor, blood–brain barrier disruption and schizophrenia: a theory with unproven links by Titulaer, M J, Dalmau, J

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From VGKC to LGI1 and Caspr2 encephalitis: the evolution of a disease entity over time by van Sonderen, A, Schreurs, M.W.J, Wirtz, P.W, Smitt, P.A.E. Sillevis, Titulaer, M.J

“…Abstract A wide variety of clinical syndromes has been associated with antibodies to voltage-gated potassium channels (VGKCs). Six years ago, it was discovered…”
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PDE10A antibodies in autoimmune encephalitis: A possible marker of cancer immunotherapy? by Titulaer, M.J, Irani, S.R, Lassmann, H

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Seizures in adults with suspected central nervous system infection by Olie, Sabine E, van Zeggeren, Ingeborg E, ter Horst, Liora, Citroen, J, van Geel, B. M, Heckenberg, S. G. B, Jellema, K, Kester, M. I, Killestein, J, Mook, B. B, Titulaer, M. J, van Veen, K. E. B, Verschuur, C. V. M

“…Abstract Background Seizures can be part of the clinical presentation of central nervous system (CNS) infections. We describe patients suspected of a…”
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Early recognition of anti-N-methyl-D-aspartate receptor encephalitis in psychiatric patients by van Mierlo, H. C., Titulaer, M. J., Kromkamp, M., van de Kraats, R., van Veelen, N. M., Palmen, S. J., Kahn, R. S., de Witte, L. D.

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Diagnostic accuracy of clinical and laboratory characteristics in suspected non-surgical nosocomial central nervous system infections by van Zeggeren, I.E., Pennartz, C.J., ter Horst, L., van de Beek, D., Brouwer, M.C., Bijlsma, M.W., Citroen, J., van Geel, B.M., Groeneveld, N.S., Heckenberg, S.G.B., Jellema, K., Kester, M.I., Killestein, J., Mook, B.B., Resok, Y.C., Olie, S.E., Staal, S.L., Titulaer, M.J., van Veen, K.E.B.

“…The diagnosis of meningitis in non-surgical hospitalized patients is often difficult and diagnostic accuracy of clinical, laboratory, and radiological…”
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Predictors of unfavourable outcome in adults with suspected central nervous system infections: a prospective cohort study by ter Horst, Liora, van Zeggeren, Ingeborg E., Olie, Sabine E., van de Beek, Diederik, Brouwer, Matthijs C.

“…Suspected central nervous system (CNS) infections may pose a diagnostic challenge, and often concern severely ill patients. We aim to identify predictors of…”
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1600 The utility of SOX antibodies for cancer prediction in patients with paraneoplastic neurological disorders by Maddison, P, Titulaer, M J, Verschuuren, J J G, Gozzard, P, Lang, B, Willcox, N, Vincent, A, Irani, S R, Chapman, C J

“…Recent studies have identified antibodies to the SOXB1 group of proteins in patients with paraneoplastic disorders (PNDs) associated with small-cell lung…”
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Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B08 by Gregersen, Peter K, Kosoy, Roman, Lee, Annette T, Lamb, Janine, Sussman, Jon, McKee, David, Simpfendorfer, Kim R, Pirskanen-Matell, Ritva, Piehl, Frederik, Pan-Hammarstrom, Qiang, Verschuuren, Jan J G M, Titulaer, Maarten J, Niks, Erik H, Marx, Alexander, Ströbel, Philipp, Tackenberg, Björn, Pütz, Michael, Maniaol, Angelina, Elsais, Ahmed, Tallaksen, Chantal, Harbo, Hanne F, Lie, Benedicte A, Raychaudhuri, Soumya, de Bakker, Paul I W, Melms, Arthur, Garchon, Henri-Jean, Willcox, Nicholas, Hammarstrom, Lennart, Seldin, Michael F

“…The objective of this study is to comprehensively define the genetic basis of early onset myasthenia gravis (EOMG). We have carried out a 2-stage genome-wide…”
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A clinical approach to diagnosis of autoimmune encephalitis by Graus, Francesc, Prof, Titulaer, Maarten J, MD, Balu, Ramani, MD, Benseler, Susanne, MD, Bien, Christian G, Prof, Cellucci, Tania, MD, Cortese, Irene, MD, Dale, Russell C, Prof, Gelfand, Jeffrey M, MD, Geschwind, Michael, MD, Glaser, Carol A, MD, Honnorat, Jerome, Prof, Höftberger, Romana, MD, Iizuka, Takahiro, MD, Irani, Sarosh R, MD, Lancaster, Eric, MD, Leypoldt, Frank, MD, Prüss, Harald, MD, Rae-Grant, Alexander, MD, Reindl, Markus, Prof, Rosenfeld, Myrna R, Prof, Rostásy, Kevin, MD, Saiz, Albert, MD, Venkatesan, Arun, MD, Vincent, Angela, Prof, Wandinger, Klaus-Peter, Prof, Waters, Patrick, PhD, Dalmau, Josep, Prof

“…Summary Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune…”
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Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study by Gresa-Arribas, Nuria, PhD, Titulaer, Maarten J, MD, Torrents, Abiguei, BS, Aguilar, Esther, McCracken, Lindsey, MPH, Leypoldt, Frank, MD, Gleichman, Amy J, PhD, Balice-Gordon, Rita, Prof, Rosenfeld, Myrna R, Prof, Lynch, David, Prof, Graus, Francesc, Prof, Dalmau, Josep, Prof

“…Summary Background Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but treatable autoimmune disorder which diagnosis depends on sensitive…”
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Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study by Titulaer, Maarten J, MD, McCracken, Lindsey, BS, Gabilondo, Iñigo, MD, Armangué, Thaís, MD, Glaser, Carol, MD, Iizuka, Takahiro, MD, Honig, Lawrence S, Prof, Benseler, Susanne M, MD, Kawachi, Izumi, MD, Martinez-Hernandez, Eugenia, MD, Aguilar, Esther, BS, Gresa-Arribas, Núria, PhD, Ryan-Florance, Nicole, MD, Torrents, Abiguei, BS, Saiz, Albert, MD, Rosenfeld, Myrna R, Prof, Balice-Gordon, Rita, Prof, Graus, Francesc, Prof, Dalmau, Josep, Prof

“…Summary Background Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune disorder in which the use of immunotherapy and the long-term outcome have not been…”
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