Search Results - "Titong, Allison"

Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2 by Dong, Jianbo, Huang, Betty, Wang, Bo, Titong, Allison, Gallolu Kankanamalage, Sachith, Jia, Zhejun, Wright, Meredith, Parthasarathy, Pannaga, Liu, Yue

“…SARS-CoV-2 is a newly emergent coronavirus, which has adversely impacted human health and has led to the COVID-19 pandemic. There is an unmet need to develop…”
Get full text

First-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants by Titong, Allison, Gallolu Kankanamalage, Sachith, Dong, Jianbo, Huang, Betty, Spadoni, Nicholas, Wang, Bo, Wright, Meredith, Pham, Keegan L. J., Le, Anh Hai, Liu, Yue

“…SARS-CoV-2 and its variants have persisted in this ongoing COVID-19 pandemic. While the vaccines have greatly reduced the COVID-19 cases, hospitalizations, and…”
Get full text

Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity by Dong, Jianbo, Huang, Betty, Jia, Zhejun, Wang, Bo, Gallolu Kankanamalage, Sachith, Titong, Allison, Liu, Yue

“…Coronaviruses cause severe human viral diseases including SARS, MERS and COVID-19. Most recently SARS-CoV-2 virus (causing COVID-19) has led to a pandemic with…”
Get full text

Author Correction: Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2 by Dong, Jianbo, Huang, Betty, Wang, Bo, Titong, Allison, Kankanamalage, Sachith Gallolu, Jia, Zhejun, Wright, Meredith, Parthasarathy, Pannaga, Liu, Yue

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Fc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response by Yang, Riyao, Huang, Su, Huang, Cai, Fay, Nathan S., Wang, Yanan, Putrevu, Saroja, Wright, Kimberly, Zaman, Mohd Saif, Cai, Wenyan, Huang, Betty, Wang, Bo, Wright, Meredith, Hoag, Matthew R., Titong, Allison, Liu, Yue

“…The landscape of current cancer immunotherapy is dominated by antibodies targeting PD-1/PD-L1 and CTLA-4 that have transformed cancer therapy, yet their…”
Get full text

Replication-inducible vaccinia virus vectors with enhanced safety in vivo by O'Connell, Caitlin M, Jasperse, Brittany, Hagen, Caitlin J, Titong, Allison, Verardi, Paulo H

“…Vaccinia virus (VACV) has been used extensively as the vaccine against smallpox and as a viral vector for the development of recombinant vaccines and cancer…”
Get full text

A vaccinia virus renaissance: New vaccine and immunotherapeutic uses after smallpox eradication by Verardi, Paulo H., Titong, Allison, Hagen, Caitlin J.

“…In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective…”
Get full text

Safety mechanism assisted by the repressor of tetracycline (SMART) vaccinia virus vectors for vaccines and therapeutics by Grigg, Patricia, Titong, Allison, Jones, Leslie A., Yilma, Tilahun D., Verardi, Paulo H.

“…Replication-competent viruses, such as Vaccinia virus (VACV), are powerful tools for the development of oncolytic viral therapies and elicit superior immune…”
Get full text

Abstract LB068: A novel CD20/CD3 T cell engager designed from Rituximab targeting CD20+ cancer with multiple mechanisms by Cai, Wenyan, Dong, Jianbo, Kankanamalage, Sachith Gallolu, Titong, Allison, Shi, Jiadong, Jia, Zhejun, Wang, Bo, Huang, Cai, Zhang, Jing, Lin, Jun, Kan, Steven Z., Zhou, Joe, Liu, Yue

“…Background Bispecific T cell engaging antibodies (TEAs) with one arm targeting a cancer antigen and another arm binding to CD3 have demonstrated impressive…”
Get full text

Antibiotic-dependent expression of early transcription factor subunits leads to stringent control of vaccinia virus replication by Hagen, Caitlin J., Titong, Allison, Sarnoski, Ethan A., Verardi, Paulo H.

“…•Uncontrolled replication of vaccinia virus vectors can lead to complications.•We placed early transcription factor genes under the control of tet operon…”
Get full text

Biological activity validation of a computationally designed Rituximab/CD3 T cell engager targeting CD20+ cancers with multiple mechanisms of action by Cai, Wenyan, Dong, Jianbo, Gallolu Kankanamalage, Sachith, Titong, Allison, Shi, Jiadong, Jia, Zhejun, Wang, Bo, Huang, Cai, Zhang, Jing, Lin, Jun, Kan, Steven Z, Han, Shuhua, Zhou, Joe, Liu, Yue

“…Abstract Background Bispecific T cell engaging antibodies (TEAs) with one arm targeting a cancer antigen and another arm binding to CD3 have demonstrated…”
Get full text

Development of Repressible Systems to Control Gene Expression in Vaccinia Virus by Titong, Allison

“…Two vaccinia virus (VACV) expression systems that contain elements from the lactose (lac) and the tetracycline (tet) operons of E. coli were developed to…”
Get full text