Search Results - "Titball, R W"

Lipoproteins of Bacterial Pathogens by Kovacs-Simon, A, Titball, R.W, Michell, S.L

“…Bacterial lipoproteins are a set of membrane proteins with many different functions. Due to this broad-ranging functionality, these proteins have a…”
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Burkholderia thailandensis strain E555 is a surrogate for the investigation of Burkholderia pseudomallei replication and survival in macrophages by Kovacs-Simon, A, Hemsley, C M, Scott, A E, Prior, J L, Titball, R W

“…Burkholderia pseudomallei is a human pathogen causing severe infections in tropical and subtropical regions and is classified as a bio-threat agent. B…”
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Salmonella Gallinarum field isolates from laying hens are related to the vaccine strain SG9R by Van Immerseel, F, Studholme, D.J, Eeckhaut, V, Heyndrickx, M, Dewulf, J, Dewaele, I, Van Hoorebeke, S, Haesebrouck, F, Van Meirhaeghe, H, Ducatelle, R, Paszkiewicz, K, Titball, R.W

“…Highlights • S. Gallinarum outbreak strains and the SG9R vaccine have identical DNA fingerprints. • Whole-genome sequencing shows 9 SNPs distinguishing an…”
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Development of Signature-Tagged Mutagenesis in Burkholderia pseudomallei To Identify Genes Important in Survival and Pathogenesis by Cuccui, J, Easton, A, Chu, K.K, Bancroft, G.J, Oyston, P.C.F, Titball, R.W, Wren, B.W

“…Burkholderia pseudomallei, the causative agent of melioidosis, is an important human pathogen in Southeast Asia and northern Australia for which a vaccine is…”
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A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface by Joshua, G. W. P, Karlyshev, A. V, Smith, M. P, Isherwood, K. E, Titball, R. W, Wren, B. W

“…1 London School of Hygiene and Tropical Medicine, Dept Infectious and Tropical Diseases, Keppel St, London WC1E 7HT, UK 2 DSTL, Porton Down, Salisbury SP4 0JQ,…”
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A Mutant of Burkholderia pseudomallei, Auxotrophic in the Branched Chain Amino Acid Biosynthetic Pathway, Is Attenuated and Protective in a Murine Model of Melioidosis by ATKINS, T, PRIOR, R. G, MACK, K, RUSSELL, P, NELSON, M, OYSTON, P. C. F, DOUGAN, G, TITBALL, R. W

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Genome sequence of Yersinia pestis , the causative agent of plague by Parkhill, J, Wren, B. W, Thomson, N. R, Titball, R. W, Holden, M. T. G, Prentice, M. B, Sebaihia, M, James, K. D, Churcher, C, Mungall, K. L, Baker, S, Basham, D, Bentley, S. D, Brooks, K, Cerdeño-Tárraga, A. M, Chillingworth, T, Cronin, A, Davies, R. M, Davis, P, Dougan, G, Feltwell, T, Hamlin, N, Holroyd, S, Jagels, K, Karlyshev, A. V, Leather, S, Moule, S, Oyston, P. C. F, Quail, M, Rutherford, K, Simmonds, M, Skelton, J, Stevens, K, Whitehead, S, Barrell, B. G

“…The Gram-negative bacterium Yersinia pestis is the causative agent of the systemic invasive infectious disease classically referred to as plague, and has been…”
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RelA regulates virulence and intracellular survival of Francisella novicida by Dean, R. E, Ireland, P. M, Jordan, J. E, Titball, R. W, Oyston, P. C. F

“…1 Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire SP4 0JQ, UK 2 School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road,…”
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Novel multi‐component vaccine approaches for Burkholderia pseudomallei by Morici, L., Torres, A. G., Titball, R. W.

“…Summary Burkholderia pseudomallei is the causative agent of melioidosis. Historically believed to be a relatively rare human disease in tropical countries, a…”
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Presymptomatic Prediction of Sepsis in Intensive Care Unit Patients by Lukaszewski, R A, Yates, A M, Jackson, M C, Swingler, K, Scherer, J M, Simpson, A J, Sadler, P, McQuillan, P, Titball, R W, Brooks, T J G, Pearce, M J

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Bacterial phospholipases C by TITBALL, R. W

“…A variety of pathogenic bacteria produce phospholipases C, and since the discovery in 1944 that a bacterial toxin (Clostridium perfringens alpha-toxin)…”
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Polysaccharides and virulence of Burkholderia pseudomallei by Sarkar-Tyson, M, Thwaite, J. E, Harding, S. V, Smither, S. J, Oyston, P. C. F, Atkins, T. P, Titball, R. W

“…1 Defence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK 2 Department of Infectious and Tropical Disease, London School of Hygiene and…”
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Clostridium perfringens phospholipase C-induced platelet/leukocyte interactions impede neutrophil diapedesis by Bryant, A. E, Bayer, C. R, Aldape, M. J, Wallace, R. J, Titball, R. W, Stevens, D. L

“…1 Infectious Diseases Section, Veterans Affairs Medical Center, Building 45, 500 West Fort Street, Boise, ID 83702, USA 2 University of Idaho, Moscow, ID, USA…”
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Kinetics of the immune response to the (F1 + V) vaccine in models of bubonic and pneumonic plague by Williamson, E.D, Stagg, A.J, Eley, S.M, Taylor, R, Green, M, Jones, S.M, Titball, R.W

“…Abstract Protection against aerosol challenge with >300 MLD of Yersinia pestis was observed 7 days after a single immunisation of mice with the F1 + V vaccine…”
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A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice by Quarry, J.E, Isherwood, K.E, Michell, S.L, Diaper, H, Titball, R.W, Oyston, P.C.F

“…Abstract Francisella tularensis subspecies novicida mutants have been made with deletions introduced into the purA or purF genes. These mutants demonstrated…”
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Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes by KARLYSHEV, A. V, OYSTON, P. C. F, WILLIAMS, K, CLARK, G. C, TITBALL, R. W, WINZELER, E. A, WREN, B. W

“…Yersinia pestis, the causative agent of plague, and the enteropathogen Yersinia pseudotuberculosis have nearly identical nucleotide similarity yet cause…”
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Protection Afforded by Heat Shock Protein 60 from Francisella tularensis Is Due to Copurified Lipopolysaccharide by HARTLEY, M. G, GREEN, M, CHOULES, G, ROGERS, D, REES, D. G. C, NEWSTEAD, S, SJOSTEDT, A, TITBALL, R. W

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An IgG1 titre to the F1 and V antigens correlates with protection against plague in the mouse model by WILLIAMSON, E. D., VESEY, P. M., GILLHESPY, K. J., ELEY, S. M., GREEN, M., TITBALL, R. W.

“…The objective of this study was to identify an immunological correlate of protection for a two‐component subunit vaccine for plague, using a mouse model. The…”
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The Response Regulator PhoP Is Important for Survival under Conditions of Macrophage-Induced Stress and Virulence in Yersinia pestis by OYSTON, P. C. F, DORRELL, N, WILLIAMS, K, LI, S.-R, GREEN, M, TITBALL, R. W, WREN, B. W

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Active immunization with recombinant V antigen from Yersinia pestis protects mice against plague by LEARY, S. E. C, WILLIAMSON, E. D, GRIFFIN, K. F, RUSSELL, P, ELEY, S. M, TITBALL, R. W

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