Search Results - "Tisserand, Johan"

Loss of Trim24 ( Tif1α ) gene function confers oncogenic activity to retinoic acid receptor alpha by Herquel, Benjamin, Zucman-Rossi, Jessica, Cammas, Florence, Khetchoumian, Konstantin, Lerouge, Thierry, Losson, Régine, Teletin, Marius, Ignat, Mihaela, Tisserand, Johan, Mark, Manuel, Chambon, Pierre, Metzger, Daniel, Thibault, Christelle

“…Hepatocellular carcinoma (HCC) is a major cause of death worldwide. Here, we provide evidence that the ligand-dependent nuclear receptor co-regulator Trim24…”
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Trim24 (Tif1α): An essential 'brake' for retinoic acid-induced transcription to prevent liver cancer by Khetchoumian, Konstantin, Teletin, Marius, Tisserand, Johan, Herquel, Benjamin, Ouararhni, Khalid, Losson, Régine

“…Retinoic acid (RA), the active derivative of vitamin A, is an important signaling molecule that controls various developmental processes and influence the…”
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Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1α by Ignat, Mihaela, Teletin, Marius, Tisserand, Johan, Khetchoumian, Konstantin, Dennefeld, Christine, Chambon, Pierre, Losson, Régine, Mark, Manuel

“…Calcification of arteries is a major risk factor for cardiovascular mortality in humans. Using genetic approaches, we demonstrate here that the transcriptional…”
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dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes by Kessler, Roman, Tisserand, Johan, Font-Burgada, Joan, Reina, Oscar, Coch, Laura, Attolini, Camille Stephan-otto, Garcia-Bassets, Ivan, Azorín, Fernando

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Tripartite Motif 24 (Trim24/Tif1α) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor α (Rarα) Inhibition by Tisserand, Johan, Khetchoumian, Konstantin, Thibault, Christelle, Dembélé, Doulaye, Chambon, Pierre, Losson, Régine

“…Recent genetic studies in mice have established that the nuclear receptor coregulator Trim24/Tif1α suppresses hepatocarcinogenesis by inhibiting retinoic acid…”
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Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32 by Gonzalez-Cano, Laura, Menzl, Ingeborg, Tisserand, Johan, Nicklas, Sarah, Schwamborn, Jens C.

“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Accumulating evidences suggest that PD might have a strong neurodevelopmental…”
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Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients by Nickels, Sarah Louise, Walter, Jonas, Bolognin, Silvia, Gérard, Deborah, Jaeger, Christian, Qing, Xiaobing, Tisserand, Johan, Jarazo, Javier, Hemmer, Kathrin, Harms, Amy, Halder, Rashi, Lucarelli, Philippe, Berger, Emanuel, Antony, Paul M.A., Glaab, Enrico, Hankemeier, Thomas, Klein, Christine, Sauter, Thomas, Sinkkonen, Lasse, Schwamborn, Jens Christian

“…Parkinson's disease (PD) is a multifactorial disorder with complex etiology. The most prevalent PD associated mutation, LRRK2-G2019S is linked to familial and…”
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dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes by Kessler, Roman, Tisserand, Johan, Font-Burgada, Joan, Reina, Oscar, Coch, Laura, Attolini, Camille Stephan-otto, Garcia-Bassets, Ivan, Azorín, Fernando

“…dDsk2 is a conserved extraproteasomal ubiquitin receptor that targets ubiquitylated proteins for degradation. Here we report that dDsk2 plays a nonproteolytic…”
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Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective population-based study differ from those of advanced GISTs by Emile, J. F., Brahimi, S., Coindre, J. M., Bringuier, P. P., Monges, G., Samb, P., Doucet, L., Hostein, I., Landi, B., Buisine, M. P., Neuville, A., Bouché, O., Cervera, P., Pretet, J. L., Tisserand, J., Gauthier, A., Le Cesne, A., Sabourin, J. C., Scoazec, J. Y., Bonvalot, S., Corless, C. L., Heinrich, M. C., Blay, J. Y., Aegerter, P.

“…Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma. Most of the data available on GISTs derive from retrospective studies of patients…”
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Trim24 (Tif1 alpha): an essential 'brake' for retinoic acid-induced transcription to prevent liver cancer by Khetchoumian, Konstantin, Teletin, Marius, Tisserand, Johan, Herquel, Benjamin, Ouararhni, Khalid, Losson, Régine

“…Retinoic acid (RA), the active derivative of vitamin A, is an important signaling molecule that controls various developmental processes and influence the…”
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Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1[alpha] by Ignat, Mihaela, Teletin, Marius, Tisserand, Johan, Khetchoumian, Konstantin, Dennefeld, Christine, Chambon, Pierre, Losson, Régine, Mark, Manuel

“…Calcification of arteries is a major risk factor for cardiovascular mortality in humans. Using genetic approaches, we demonstrate here that the transcriptional…”
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Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha by Ignat, Mihaela, Teletin, Marius, Tisserand, Johan, Khetchoumian, Konstantin, Dennefeld, Christine, Chambon, Pierre, Losson, Régine, Mark, Manuel

“…Calcification of arteries is a major risk factor for cardiovascular mortality in humans. Using genetic approaches, we demonstrate here that the transcriptional…”
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Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth by Fadloun, A, Kobi, D, Delacroix, L, Dembélé, D, Michel, I, Lardenois, A, Tisserand, J, Losson, R, Mengus, G, Davidson, I

“…To evaluate the role of murine TFIID subunit TAF4 in activation of cellular genes by all-trans retinoic acid (T-RA), we have characterized the T-RA response of…”
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