Search Results - "Tischler, Julia"
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Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways
Published in Nature genetics (01-08-2006)“…Most heritable traits, including disease susceptibility, are affected by interactions between multiple genes. However, we understand little about how genes…”
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Evolutionary plasticity of genetic interaction networks
Published in Nature genetics (01-04-2008)“…Non-additive genetic interactions contribute to many genetic disorders, but they are extremely difficult to predict. Here we show that genetic interactions…”
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Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase 1
Published in Molecular and Cellular Biology (01-11-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Cyclin-Dependent Kinase Inhibitor p21 Is a Crucial Target for Histone Deacetylase 1 as a Regulator of Cellular Proliferation
Published in Molecular and Cellular Biology (01-03-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Examining African contributions to global health: Reflections on knowledge circulation and innovation
Published in Global public health (2023)“…This article unites different disciplinary debates on 'southern innovation', 'theory from the South', and 'decolonisation of knowledge' in order to discuss…”
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The Tumor Suppressor p53 and Histone Deacetylase 1 Are Antagonistic Regulators of the Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1 Gene
Published in Molecular and Cellular Biology (01-04-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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“The Only Industry That Can Make Us Hold Our Own”: Black Agrarianism in South Africa from a Transatlantic Perspective, ca. 1910–1930
Published in The American historical review (09-02-2022)“…Abstract By exploring agricultural education initiatives in South Africa in the period from the 1910s to the 1930s, this article seeks to expand the…”
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EDUCATION AND THE AGRARIAN QUESTION IN SOUTH AFRICA, c. 1900–40
Published in Journal of African history (01-07-2016)“…During the first half of the twentieth century, deep structural changes occurred in the South African countryside. While farming became an important pillar of…”
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Cementing Uneven Development: The Central African Federation and the Kariba Dam Scheme
Published in Journal of southern African studies (03-09-2014)“…Using the Kariba dam project as a case study, this article examines some of the biases and interdependencies of development planning in 1950s Northern Rhodesia…”
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Stem cells: a sporadic super state
Published in Nature (London) (04-07-2012)Get full text
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Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate
Published in The EMBO journal (03-01-2019)“…An intricate link is becoming apparent between metabolism and cellular identities. Here, we explore the basis for such a link in an in vitro model for early…”
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Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells
Published in Molecular cell (17-07-2014)“…Cell populations can be strikingly heterogeneous, composed of multiple cellular states, each exhibiting stochastic noise in its gene expression. A major…”
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A sporadic super state
Published in Nature (London) (05-07-2012)“…It seems that embryonic stem cells regularly pass through a transient state during which they can generate all the cell types of an animal, including those of…”
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Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
Published in EMBO reports (01-07-2013)“…Primordial germ cells (PGCs) and somatic cells originate from postimplantation epiblast cells in mice. As pluripotency is lost upon differentiation of somatic…”
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Investigating transcriptional states at single-cell-resolution
Published in Current opinion in biotechnology (01-02-2013)“…Graphical abstract. Highlights ► We discuss the importance and challenges of single-cell transcript profiling methods. ► We present whole-genome single-cell…”
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RNAi screens in Caenorhabditis elegans in a 96-well liquid format and their application to the systematic identification of genetic interactions
Published in Nature protocols (01-11-2006)“…We describe a protocol for performing RNA interference (RNAi) screens in Caenorhabditis elegans in liquid culture in 96-well plates. The procedure allows a…”
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An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates
Published in Cell reports methods (24-10-2022)Get full text
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Erratum: An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates
Published in Cell reports methods (24-10-2022)Get full text
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An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates
Published in Cell reports methods (18-07-2022)“…We present a low-cost, do-it-yourself system for complex mammalian cell culture under dynamically changing medium formulations by integrating conventional…”
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