Search Results - "Tischfield, J."

Generation of cerebral cortical GABAergic interneurons from pluripotent stem cells by Fitzgerald, Megan, Sotuyo, Nathaniel, Tischfield, David J., Anderson, Stewart A.

“…The cerebral cortex functions by the complex interactions of intrinsic and extrinsic neuronal activities, glial actions, and the effects of humoral factors…”
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RORβ induces barrel-like neuronal clusters in the developing neocortex by Jabaudon, Denis, Shnider, Sara J, Tischfield, David J, Galazo, Maria J, Macklis, Jeffrey D

“…Neurons in layer IV of the rodent whisker somatosensory cortex are tangentially organized in periodic clusters called barrels, each of which is innervated by…”
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Gene expression in major depressive disorder by Jansen, R, Penninx, B W J H, Madar, V, Xia, K, Milaneschi, Y, Hottenga, J J, Hammerschlag, A R, Beekman, A, van der Wee, N, Smit, J H, Brooks, A I, Tischfield, J, Posthuma, D, Schoevers, R, van Grootheest, G, Willemsen, G, de Geus, E J, Boomsma, D I, Wright, F A, Zou, F, Sun, W, Sullivan, P F

“…The search for genetic variants underlying major depressive disorder (MDD) has not yet provided firm leads to its underlying molecular biology. A complementary…”
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Position and orientation of vaginal pessaries in situ on magnetic resonance imaging by Hong, Christopher X., Meer, Elana, Cioban, Max, Tischfield, David J., Hassani, Daisy B., Harvie, Heidi S.

“…Introduction and hypothesis We hypothesize that there are differences in the position and orientation of ring and Gellhorn pessaries in situ on magnetic…”
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Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation by Tischfield, David J, Saraswat, Dave K, Furash, Andrew, Fowler, Stephen C, Fuccillo, Marc V, Anderson, Stewart A

“…Abstract The zinc-finger SWIM domain-containing protein 6 (ZSWIM6) is a protein of unknown function that has been associated with schizophrenia and limited…”
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ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry by Bierut, L J, Goate, A M, Breslau, N, Johnson, E O, Bertelsen, S, Fox, L, Agrawal, A, Bucholz, K K, Grucza, R, Hesselbrock, V, Kramer, J, Kuperman, S, Nurnberger, J, Porjesz, B, Saccone, N L, Schuckit, M, Tischfield, J, Wang, J C, Foroud, T, Rice, J P, Edenberg, H J

“…A coding variant in alcohol dehydrogenase 1B ( ADH1B ) (rs1229984) that leads to the replacement of Arg48 with His48 is common in Asian populations and reduces…”
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CC2D1A Regulates Human Intellectual and Social Function as well as NF-κB Signaling Homeostasis by Manzini, M. Chiara, Xiong, Lan, Shaheen, Ranad, Tambunan, Dimira E., Di Costanzo, Stefania, Mitisalis, Vanessa, Tischfield, David J., Cinquino, Antonella, Ghaziuddin, Mohammed, Christian, Mehtab, Jiang, Qin, Laurent, Sandra, Nanjiani, Zohair A., Rasheed, Saima, Hill, R. Sean, Lizarraga, Sofia B., Gleason, Danielle, Sabbagh, Diya, Salih, Mustafa A., Alkuraya, Fowzan S., Walsh, Christopher A.

“…Autism spectrum disorder (ASD) and intellectual disability (ID) are often comorbid, but the extent to which they share common genetic causes remains…”
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The PNKD gene is associated with Tourette Disorder or Tic disorder in a multiplex family by Sun, N, Nasello, C, Deng, L, Wang, N, Zhang, Y, Xu, Z, Song, Z, Kwan, K, King, R A, Pang, Z P, Xing, J, Heiman, G A, Tischfield, J A

“…Tourette Disorder (TD) is a childhood-onset neuropsychiatric and neurodevelopmental disorder characterized by the presence of both motor and vocal tics. The…”
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Tumor resident mesenchymal stromal cells endow naïve stromal cells with tumor-promoting properties by Ren, G, Liu, Y, Zhao, X, Zhang, J, Zheng, B, Yuan, Z-R, Zhang, L, Qu, X, Tischfield, J A, Shao, C, Shi, Y

“…Bone marrow mesenchymal stem/stromal cells (BM-MSCs) can infiltrate into tumors and subsequently evolve into tumor resident MSCs in tumor microenvironment. In…”
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Genome-wide association study identifies a novel locus for cannabis dependence by Agrawal, A, Chou, Y-L, Carey, C E, Baranger, D A A, Zhang, B, Sherva, R, Wetherill, L, Kapoor, M, Wang, J-C, Bertelsen, S, Anokhin, A P, Hesselbrock, V, Kramer, J, Lynskey, M T, Meyers, J L, Nurnberger, J I, Rice, J P, Tischfield, J, Bierut, L J, Degenhardt, L, Farrer, L A, Gelernter, J, Hariri, A R, Heath, A C, Kranzler, H R, Madden, P A F, Martin, N G, Montgomery, G W, Porjesz, B, Wang, T, Whitfield, J B, Edenberg, H J, Foroud, T, Goate, A M, Bogdan, R, Nelson, E C

“…Despite moderate heritability, only one study has identified genome-wide significant loci for cannabis-related phenotypes. We conducted meta-analyses of…”
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Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence by Wang, J C, Grucza, R, Cruchaga, C, Hinrichs, A L, Bertelsen, S, Budde, J P, Fox, L, Goldstein, E, Reyes, O, Saccone, N, Saccone, S, Xuei, X, Bucholz, K, Kuperman, S, Nurnberger, J, Rice, J P, Schuckit, M, Tischfield, J, Hesselbrock, V, Porjesz, B, Edenberg, H J, Bierut, L J, Goate, A M

“…Alcohol dependence frequently co-occurs with cigarette smoking, another common addictive behavior. Evidence from genetic studies demonstrates that alcohol…”
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Protecting genomic integrity in somatic cells and embryonic stem cells by Hong, Y, Cervantes, R B, Tichy, E, Tischfield, J A, Stambrook, P J

“…Mutation frequencies at some loci in mammalian somatic cells in vivo approach 10(-4). The majority of these events occur as a consequence of loss of…”
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Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells by Tischfield, David J., Kim, Junho, Anderson, Stewart A.

“…Recent studies indicate that the location of neurogenesis within the medial ganglionic eminence (MGE) critically influences the fate determination of cortical…”
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Gene expression in major depressive disorder by Jansen, R, Penninx, B W J H, Madar, V, Xia, K, Milaneschi, Y, Hottenga, J J, Hammerschlag, A R, Beekman, A, van der Wee, N, Smit, J H, Brooks, A I, Tischfield, J, Posthuma, D, Schoevers, R, van Grootheest, G, Willemsen, G, de Geus, E J, Boomsma, D I, Wright, F A, Zou, F, Sun, W, Sullivan, P F

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Association of the κ-opioid system with alcohol dependence by XUEI, X, DICK, D, TISCHFIELD, J, KUPERMAN, S, PORJESZ, B, BEGLEITER, H, FOROUD, T, EDENBERG, H. J, FLURY-WETHERILL, L, TIAN, H.-J, AGRAWAL, A, BIERUT, L, GOATE, A, BUCHOLZ, K, SCHUCKIT, M, NURNBERGER, J

“…Opioid receptors and their endogenous peptide ligands play important roles in the reward and reinforcement of drugs such as heroin, cocaine, and alcohol. The…”
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Common biological networks underlie genetic risk for alcoholism in African‐ and European‐American populations by Kos, M. Z., Yan, J., Dick, D. M., Agrawal, A., Bucholz, K. K., Rice, J. P., Johnson, E. O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A. M., Tischfield, J. A., Foroud, T., Nurnberger, J., Hesselbrock, V., Porjesz, B., Bierut, L. J., Edenberg, H. J., Almasy, L.

“…Alcohol dependence (AD) is a heritable substance addiction with adverse physical and psychological consequences, representing a major health and economic…”
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Family‐based genome‐wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6 by Kang, S. J., Rangaswamy, M., Manz, N., Wang, J.‐C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D. B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L. J., Edenberg, H. J., Goate, A., Foroud, T., Porjesz, B.

“…Event‐related oscillations (EROs) represent highly heritable neuroelectric correlates of cognitive processes that manifest deficits in alcoholics and in…”
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Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior by Salvatore, J E, Edwards, A C, McClintick, J N, Bigdeli, T B, Adkins, A, Aliev, F, Edenberg, H J, Foroud, T, Hesselbrock, V, Kramer, J, Nurnberger, J I, Schuckit, M, Tischfield, J A, Xuei, X, Dick, D M

“…Adult antisocial behavior (AAB) is moderately heritable, relatively common and has adverse consequences for individuals and society. We examined the molecular…”
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Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures by Kapoor, M, Chou, Y-L, Edenberg, H J, Foroud, T, Martin, N G, Madden, P A F, Wang, J C, Bertelsen, S, Wetherill, L, Brooks, A, Chan, G, Hesselbrock, V, Kuperman, S, Medland, S E, Montgomery, G, Tischfield, J, Whitfield, J B, Bierut, L J, Heath, A C, Bucholz, K K, Goate, A M, Agrawal, A

“…Age at onset of alcohol dependence (AO-AD) is a defining feature of multiple drinking typologies. AO-AD is heritable and likely shares genetic liability with…”
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Genome-wide search for genes affecting the risk for alcohol dependence by Reich, Theodore, Edenberg, Howard J., Goate, Alison, Williams, Jeff T., Rice, John P., Van Eerdewegh, Paul, Foroud, Tatiana, Hesselbrock, Victor, Schuckit, Marc A., Bucholz, Kathleen, Porjesz, Bernice, Li, Ting-Kai, Conneally, P. Michael, Nurnberger Jr, John I., Tischfield, Jay A., Crowe, Raymond R., Cloninger, C. Robert, Wu, William, Shears, Shantia, Carr, Kristie, Crose, Candice, Willig, Chris, Begleiter, Henri

“…Alcohol dependence is a leading cause of morbidity and premature death. Several lines of evidence suggest a substantial genetic component to the risk for…”
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