Search Results - "Tirumalai, Radhakrishna"

Clarifications on the Intended Use of USP Microbiological Examination of Nonsterile Products: Microbial Enumeration Tests by Tidswell, Edward C, Tirumalai, Radhakrishna S, Gross, Deborah D

“…In the execution of its legislated responsibilities, the United States Food and Drug Administration commonly refers to standard test methods detailed in the…”
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Characterization of the Low Molecular Weight Human Serum Proteome by Tirumalai, Radhakrishna S, Chan, King C, Prieto, DaRue A, Issaq, Haleem J, Conrads, Thomas P, Veenstra, Timothy D

“…Serum potentially carries an archive of important histological information whose determination could serve to improve early disease detection. The analysis of…”
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The Human Plasma Proteome by Anderson, N. Leigh, Polanski, Malu, Pieper, Rembert, Gatlin, Tina, Tirumalai, Radhakrishna S., Conrads, Thomas P., Veenstra, Timothy D., Adkins, Joshua N., Pounds, Joel G., Fagan, Richard, Lobley, Anna

“…We have merged four different views of the human plasma proteome, based on different methodologies, into a single nonredundant list of 1175 distinct gene…”
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Flexibility in DNA Recombination: Structure of the Lambda Integrase Catalytic Core by Kwon, Hyock Joo, Tirumalai, Radhakrishna, Landy, Arthur, Ellenberger, Tom

“…Lambda integrase is archetypic of site-specific recombinases that catalyze intermolecular DNA rearrangements without energetic input. DNA cleavage, strand…”
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The Catalytic Domain of λ Site-Specific Recombinase by Tirumalai, Radhakrishna S., Healey, Erica, Landy, Arthur

“…The Escherichia coli phage λ integrase protein (Int) belongs to the large Int family of site-specific recombinases. It is a heterobivalent DNA binding protein…”
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SELDI-TOF MS for diagnostic proteomics by ISSAQ, Haleem J

“…By combining chromatographic retention with MS, SELDI-TOF MS can generate protein profiles from as little as 1 (mu)L of serum or as few as 25-50 cells. The…”
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Recognition of core-type DNA sites by λ integrase by Tirumalai, Radhakrishna S, Kwon, Hyock Joo, Cardente, Erica Healey, Ellenberger, Tom, Landy, Arthur

“…Escherichia coli phage λ integrase (Int) is a 40 kilodalton, 356 amino acid residue protein, which belongs to the λ Int family of site-specific recombinases…”
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The human plasma proteome: a nonredundant list developed by combination of four separate sources by Anderson, N Leigh, Polanski, Malu, Pieper, Rembert, Gatlin, Tina, Tirumalai, Radhakrishna S, Conrads, Thomas P, Veenstra, Timothy D, Adkins, Joshua N, Pounds, Joel G, Fagan, Richard, Lobley, Anna

“…We have merged four different views of the human plasma proteome, based on different methodologies, into a single nonredundant list of 1175 distinct gene…”
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Peer Reviewed: SELDI-TOF MS for Diagnostic Proteomics by ISSAQ, Haleem J., CONRADS, Thomas P., PRIETO, DaRue A., TIRUMALAI, Radhakrishna, D.VEENSTRA, Timothy

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Using the monocyte activation test as a stand-alone release test for medical devices by Brown, Jeffrey, Clippinger, Amy J, Fritz Briglia, Claire, Casey, Warren, Coleman, Kelly, Fritsch, Anja, Hartung, Thomas, Maouyo, Djik, Muller, Thierry, Reich, Johannes, Robert, Laure, Roeder, Ruth, Sanchez, Guillermo, Sawyer, Anita Y, Solati, Shabnam, Tirumalai, Radhakrishna, Zwisler, Walter, Allen, David

“…Monocyte activation tests (MAT) are widely available but rarely used in place of animal-based pyrogen tests for safety assessment of medical devices. To…”
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SELDI-TOF MS for diagnostic proteomics by Issaq, Haleem J, Conrads, Thomas P, Prieto, DaRue A, Tirumalai, Radhakrishna, Veenstra, Timothy D

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Similarities and differences among 105 members of the Int family of site-specific recombinases by Nunes-Düby, Simone E., Kwon, Hyock Joo, Tirumalai, Radhakrishna S., Ellenberger, Tom, Landy, Arthur

“…Alignments of 105 site-specific recombinases belonging to the Int family of proteins identified extended areas of similarity and three types of structural…”
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Photoaffinity labeling of the primer binding domain in murine leukemia virus reverse transcriptase by Tirumalai, Radhakrishna S, Modak, Mukund J

“…We have labeled the primer binding domain of murine leukemia virus reverse transcriptase (MuLV RT) by covalently cross-linking 5' end labeled d(T)8 to MuLV RT,…”
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USP Proposes a New Chapter for Rapid Sterility Testing by Tirumalai, Radhakrishna S

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Site-specific Photo-cross-linking between λ Integrase and Its DNA Recombination Target by Margaret J. Kovach, Radhakrishna Tirumalai, Arthur Landy

“…The site-specific recombinase (Int) of bacteriophage λ is a heterobivalent DNA-binding protein and is composed of three domains as follows: an amino-terminal…”
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Site-specific Photo-cross-linking between λ Integrase and Its DNA Recombination Target by Kovach, Margaret J., Tirumalai, Radhakrishna, Landy, Arthur

“…The site-specific recombinase (Int) of bacteriophage λ is a heterobivalent DNA-binding protein and is composed of three domains as follows: an amino-terminal…”
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Differential Affinity and Cooperativity Functions of the Amino-terminal 70 Residues of λ Integrase by Sarkar, Dibyendu, Azaro, Marco A, Aihara, Hideki, Papagiannis, Christie V, Tirumalai, Radhakrishna, Nunes-Düby, Simone E, Johnson, Reid C, Ellenberger, Tom, Landy, Arthur

“…The site-specific recombinase (Int) of bacteriophage λ is a heterobivalent DNA-binding protein that binds two different classes of DNA-binding sites within its…”
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Identification and Characterization of the N-Ethylmaleimide-sensitive Site in λ-Integrase by Tirumalai, Radhakrishna S., Pargellis, Christopher A., Landy, Arthur

“…Integrase (Int) of bacteriophage λ is a heterobivalent DNA-binding protein and a type I topoisomerase. Upon modification with N-ethylmaleimide (NEM), a…”
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Peer Reviewed: SELDI-TOF MS for Diagnostic Proteomics: By combining chromatographic retention with MS, SELDI-TOF MS can generate protein profiles from as little as 1 μL of serum or as few as 25–50 cells by Issaq, Haleem J, Conrads, Thomas P, Prieto, DaRue A, Tirumalai, Radhakrishna, D.Veenstra, Timothy

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Identification and Characterization of the N-Ethylmaleimide-sensitive Site in λ-Integrase by Radhakrishna S. Tirumalai, Christopher A. Pargellis, Arthur Landy

“…Integrase (Int) of bacteriophage λ is a heterobivalent DNA-binding protein and a type I topoisomerase. Upon modification with N -ethylmaleimide (NEM), a…”
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