Search Results - "Tirodkar, Tejas S"

MUC1 positive, Kras and Pten driven mouse gynecologic tumors replicate human tumors and vary in survival and nuclear grade based on anatomical location by Tirodkar, Tejas S, Budiu, Raluca A, Elishaev, Esther, Zhang, Lixin, Mony, Jyothi T, Brozick, Joan, Edwards, Robert P, Vlad, Anda M

“…Activating mutations of Kras oncogene and deletions of Pten tumor suppressor gene play important roles in cancers of the female genital tract. We developed…”
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Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner by Tirodkar, Tejas S., Lu, Ping, Bai, Aiping, Scheffel, Matthew J., Gencer, Salih, Garrett-Mayer, Elizabeth, Bielawska, Alicja, Ogretmen, Besim, Voelkel-Johnson, Christina

“…A family of six ceramide synthases with distinct but overlapping substrate specificities is responsible for generation of ceramides with acyl chains ranging…”
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Anti-PD-L1 prolongs survival and triggers T cell but not humoral anti-tumor immune responses in a human MUC1-expressing preclinical ovarian cancer model by Mony, Jyothi Thyagabhavan, Zhang, Lixin, Ma, Tianzhou, Grabosch, Shannon, Tirodkar, Tejas S., Brozick, Joan, Tseng, George, Elishaev, Esther, Edwards, Robert P., Huang, Xin, Vlad, Anda M.

“…Monoclonal antibodies that block inhibitory immune checkpoint molecules and enhance anti-tumor responses show clinical promise in advanced solid tumors. Most…”
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