Search Results - "Tirado, Felipe"

Cryptococcus neoformans: historical curiosity to modern pathogen by Srikanta, Deepa, Santiago‐Tirado, Felipe H, Doering, Tamara L

“…The importance of the Basidiomycete Cryptococcus neoformans to human health has stimulated its development as an experimental model for both basic physiology…”
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False friends: Phagocytes as Trojan horses in microbial brain infections by Santiago-Tirado, Felipe H, Doering, Tamara L

“…Because the brain microvascular endothelial cells (BMECs) of the BBB are joined by tight junctions and embedded in a proteinaceous matrix [3], transmigrating…”
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Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens? by Stuckey, Peter V, Santiago-Tirado, Felipe H

“…Fungal infections represent a major, albeit neglected, public health threat with serious medical and economic burdens globally. With unacceptably high…”
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Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans -Golgi network by Santiago-Tirado, Felipe H, Bretscher, Anthony

“…Cell polarity in eukaryotes requires constant sorting, packaging and transport of membrane-bound cargo within the cell. These processes occur in two sorting…”
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Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen by Santiago-Tirado, Felipe H, Onken, Michael D, Cooper, John A, Klein, Robyn S, Doering, Tamara L

“…The blood-brain barrier (BBB) protects the central nervous system (CNS) by restricting the passage of molecules and microorganisms. Despite this barrier,…”
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An Atypical ABC Transporter Is Involved in Antifungal Resistance and Host Interactions in the Pathogenic Fungus Cryptococcus neoformans by Winski, Christopher J, Qian, Yuanyuan, Mobashery, Shahriar, Santiago-Tirado, Felipe H

“…ATP-binding cassette (ABC) transporters represent one of the largest protein superfamilies. Functionally diverse, ABC transporters have been implicated in many…”
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A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome by Santiago-Tirado, Felipe H, Peng, Tao, Yang, Meng, Hang, Howard C, Doering, Tamara L

“…Cryptococcus neoformans is an opportunistic yeast that kills over 625,000 people yearly through lethal meningitis. Host phagocytes serve as the first line of…”
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Adaptation and psychometric evaluation of the Fear of COVID-19 Scale in the general Colombian population by Cassiani-Miranda, Carlos Arturo, Tirado-Otálvaro, Andrés Felipe, Campo-Arias, Adalberto

“…The study aimed to adapt and explore the psychometric performance of the Fear of COVID-19 Scale (FCV-19S) in the general Colombian population. The original…”
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Scalable performance analysis method for SPMD applications by Tirado, Felipe, Wong, Alvaro, Rexachs, Dolores, Luque, Emilio

“…The analysis of parallel scientific applications allows us to understand their computational and communication behavior. One way of obtaining performance…”
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PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast by Santiago-Tirado, Felipe H., Legesse-Miller, Aster, Schott, Daniel, Bretscher, Anthony

“…Cell polarity involves transport of specific membranes and macromolecules at the right time to the right place. In budding yeast, secretory vesicles are…”
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Phenotypic characterization of HAM1 , a novel mating regulator of the fungal pathogen Cryptococcus neoformans by Arsenault Yee, Elizabeth, Ross, Robbi L, Santiago-Tirado, Felipe H

“…is a fungal pathogen responsible for >200,000 yearly cases with a mortality as high as 81%. This burden results, in part, from an incomplete understanding of…”
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Proposal of a scale for COVID-19 stigma-discrimination toward health workers by Campo-Arias, Adalberto, Álvarez-Solorza, Isabel, Tirado-Otálvaro, Andrés Felipe, Cassiani-Miranda, Carlos Arturo

“…Robust diagonally weighted least squares were used as the extraction method, with a tetrachoric correlation matrix for factor extraction; this method is…”
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Advanced genetic techniques in fungal pathogen research by Ross, Robbi L, Santiago-Tirado, Felipe H

“…Although fungi have been important model organisms for solving genetic, molecular, and ecological problems, recently, they are also becoming an important…”
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Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way by Santiago-Burgos, Emmanuel J, Stuckey, Peter V, Santiago-Tirado, Felipe H

“…Understanding of how intracellular pathogens survive in their host cells is important to improve management of their diseases. This has been fruitful for…”
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The ER Protein Translocation Channel Subunit Sbh1 Controls Virulence of Cryptococcus neoformans by Santiago-Tirado, Felipe H, Hurtaux, Thomas, Geddes-McAlister, Jennifer, Nguyen, Duy, Helms, Volkhard, Doering, Tamara L, Römisch, Karin

“…The fungal pathogen Cryptococcus neoformans is distinguished by a cell-wall-anchored polysaccharide capsule that is critical for virulence. Biogenesis of both…”
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Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors by Hevia, María José, Castro, Patricio, Pinto, Katherine, Reyna-Jeldes, Mauricio, Rodríguez-Tirado, Felipe, Robles-Planells, Claudia, Ramírez-Rivera, Sebastián, Madariaga, Juan Andrés, Gutierrez, Felipe, López, Javier, Barra, Marcelo, De la Fuente-Ortega, Erwin, Bernal, Giuliano, Coddou, Claudio

“…Gastric cancer (GC) is the one of the most prevalent cancers and one of the leading causes of cancer-induced deaths. Previously, we found that the expression…”
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An In Vitro Brain Endothelial Model for Studies of Cryptococcal Transmigration into the Central Nervous System by Santiago-Tirado, Felipe H, Klein, Robyn S, Doering, Tamara L

“…Cryptococcus neoformans is an environmental yeast found worldwide that causes lethal brain infections, particularly in immunocompromised hosts. In 2016, there…”
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mSphere of Influence: the Power of Yeast Genetics Still Going Strong by Santiago-Tirado, Felipe H

“…Felipe Santiago-Tirado studies the cell biology of cryptococcal infections. In this mSphere of Influence article, he reflects on how the papers "Systematic…”
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Predicting Bacterial Antibiotic Resistance using MALDI-TOF Mass Spectrometry Databases with ELM Applications by Tirado, Felipe, Lopez Cortez, Xaviera, Macaya Mejías, Vicente, Zabala-Blanco, David, Manríquez-Troncoso, José M., Ahumada-García, Roberto

“…Early detection of antibiotic resistance is a crucial task, especially for vulnerable patients under prolonged treatments with a single antibiotic. To solve…”
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Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response by Gish, Stacey R, Maier, Ezekiel J, Haynes, Brian C, Santiago-Tirado, Felipe H, Srikanta, Deepa L, Ma, Cynthia Z, Li, Lucy X, Williams, Matthew, Crouch, Erika C, Khader, Shabaana A, Brent, Michael R, Doering, Tamara L

“…Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and…”
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