Search Results - "Tipton, K F"

Nature of inhibition of mitochondrial respiratory complex I by 6-Hydroxydopamine by Glinka, Y, Tipton, K F, Youdim, M B

“…The catecholaminergic neurotoxin 6-hydroxydopamine causes parkinsonian symptoms in animals and it has been proposed that reactive oxygen species and oxidative…”
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Extracellular levels of amino acids and choline in human high grade gliomas: an intraoperative microdialysis study by Bianchi, L, De Micheli, E, Bricolo, A, Ballini, C, Fattori, M, Venturi, C, Pedata, F, Tipton, K F, Della Corte, L

“…The concentrations of endogenous amino acids and choline in the extracellular fluid of human cerebral gliomas have been measured, for the first time, by in…”
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Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices by Bianchi, L., Della Corte, L., Tipton, K.F.

“…A HPLC method, involving pre-column derivatisation with o-phthalaldehyde and fluorescence detection, is described. It allows the resolution of aspartate,…”
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Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds by Tipton, K F, Singer, T P

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ExplorEnz: the primary source of the IUBMB enzyme list by McDonald, Andrew G, Boyce, Sinéad, Tipton, Keith F

“…ExplorEnz is the MySQL database that is used for the curation and dissemination of the International Union of Biochemistry and Molecular Biology (IUBMB) Enzyme…”
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Renalase, a catecholamine-metabolising enzyme? by Boomsma, F, Tipton, K F

“…Recently, a new FAD-dependent amine oxidase, renalase, was described. It was secreted by the kidney into the blood and shown to have significant cardiovascular…”
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Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle by McCullagh, K J, Poole, R C, Halestrap, A P, Tipton, K F, O'Brien, M, Bonen, A

“…We examined whether chronic stimulation of red and white rat muscles increased the concentrations of the monocarboxylate transporter MCT1. Red and white…”
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Factors affecting the relative importance of amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans by Strolin Benedetti, M, Tipton, K F, Whomsley, R, Baltes, E

“…The monooxygenases and the amine oxidases (AOs) are the major enzyme systems involved in vivo in the oxidative metabolism of xenobiotic amines in humans. With…”
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In vitro cytotoxicity of a composite resin and compomer by Quinlan, C. A., Zisterer, D. M., Tipton, K. F., O'Sullivan, M. I.

“…Aim This work was designed to investigate the potential cytotoxicity of two of the newer dental restorative materials, Spectrum® composite resin and Dyract® AP…”
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Oxidative phosphorylation by in situ synaptosomal mitochondria from whole brain of young and old rats by Joyce, O. J. P., Farmer, M. K., Tipton, K. F., Porter, R. K.

“…Synaptosomes, isolated from the whole brain of young (3 months) and old (24 months) rats were used to study the major bioenergetic systems of neuronal…”
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Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease by Youdim, M.B.H, Tipton, K.F

“…Rats were injected intraperitoneally with varying doses of l-deprenyl (selegiline) followed 2 h later by 30 mg kg −1 2-phenylethylamine (PEA), administered in…”
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It can be a complicated life being an enzyme by Tipton, K F, O'Sullivan, M I, Davey, G P, O'Sullivan, J

“…It is becoming increasingly apparent that many well-known enzymes have alternative non-enzymic functions. Similarly, several proteins that were identified as…”
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Potentiation of mitochondrial Ca2+ sequestration by taurine by PALMI, M, YOUMBI, G. T, FUSI, F, SGARAGLI, G. P, DIXON, H. B. F, FROSINI, M, TIPTON, K. F

“…The effects of taurine (2-aminoethanesulphonic acid) and its analogues, 2-aminoethylarsonic acid, 2-hydroxyethanesulphonic (isethionic) acid,…”
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The use of taurine analogues to investigate taurine functions and their potential therapeutic applications by Della Corte, L, Crichton, R R, Duburs, G, Nolan, K, Tipton, K F, Tirzitis, G, Ward, R J

“…Despite the multitude of evidence for the beneficial effects of taurine supplementation in a variety of disease, the underlying modifying action of taurine…”
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Mechanism of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine and its prevention by desferrioxamine by Glinka, Yelena, Tipton, Keith F, Youdim, Moussa B.H

“…Inhibition of mitochondrial complex I by 6-hydroxydopamine was studied in brain and liver preparations. NADH–quinone reductase activity of this complex from…”
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Inhibition of monoamine oxidase modulates the behaviour of semicarbazide-sensitive amine oxidase (SSAO) by Fitzgerald, D H, Tipton, K F

“…The specific activity and kinetic behaviour of semicarbazide-sensitive amine oxidase (EC 1.4.3.6; SSAO) towards benzylamine, in the rat heart, is affected by…”
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Activation of human lung semicarbazide sensitive amine oxidase by a low molecular weight component present in human plasma by Dalfó, E., Hernandez, M., Lizcano, J.M., Tipton, K.F., Unzeta, M.

“…Semicarbazide-sensitive amine oxidase (SSAO) encodes a wide family of enzymes named E.C.1.4.3.6 [amine:oxygen oxidoreductase (deaminating) (copper containing)]…”
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Platelet MAO activity in subtypes of alcoholics and controls in a homogenous population by Farren, C.K., Clare, A.W., Tipton, K.F., Dinan, T.G.

“…The level of platelet monoamine oxidase (MAO) activity has been found to vary between alcoholics and healthy controls and between subtypes of alcoholics, in…”
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Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode by DAVEY, G. P, TIPTON, K. F, MURPHY, M. P

“…The compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes selective destruction of nigrostriatal dopaminergic neurons in primates, giving rise to…”
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TRAIT MARKERS FOR ALCOHOLISM: CLINICAL UTILITY by Farren, Conor K., Tipton, Keith F.

“…Because alcoholism is a multi-factorial psychiatric disorder, with both psychosocial and biochemical/genetic factors leading to its manifestation in any one…”
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