Search Results - "Tipanee, Jaitip"

Transposons: Moving Forward from Preclinical Studies to Clinical Trials by Tipanee, Jaitip, VandenDriessche, Thierry, Chuah, Marinee K

“…Transposons have emerged as promising vectors for gene therapy that can potentially overcome some of the limitations of commonly used viral vectors…”
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Preclinical and clinical advances in transposon-based gene therapy by Tipanee, Jaitip, Chai, Yoke Chin, VandenDriessche, Thierry, Chuah, Marinee K

“…Transposons derived from (SB), (PB), or typically require cotransfection of transposon DNA with a transposase either as an expression plasmid or mRNA…”
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Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells by Dastidar, Sumitava, Ardui, Simon, Singh, Kshitiz, Majumdar, Debanjana, Nair, Nisha, Fu, Yanfang, Reyon, Deepak, Samara, Ermira, Gerli, Mattia F M, Klein, Arnaud F, De Schrijver, Wito, Tipanee, Jaitip, Seneca, Sara, Tulalamba, Warut, Wang, Hui, Chai, Yoke Chin, In't Veld, Peter, Furling, Denis, Tedesco, Francesco Saverio, Vermeesch, Joris R, Joung, J Keith, Chuah, Marinee K, VandenDriessche, Thierry

“…Abstract CRISPR/Cas9 is an attractive platform to potentially correct dominant genetic diseases by gene editing with unprecedented precision. In the current…”
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Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons by Tipanee, Jaitip, Di Matteo, Mario, Tulalamba, Warut, Samara-Kuko, Ermira, Keirsse, Jiri, Van Ginderachter, Jo A., Chuah, Marinee Khim, VandenDriessche, Thierry

“…We established a semi-high-throughput in vivo screening platform using hyperactive piggyBac (hyPB) transposons (designated as PB-miR) to identify microRNAs…”
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UNIVERSAL ALLOGENEIC CAR T CELLS ENGINEERED WITH SLEEPING BEAUTY TRANSPOSONS AND CRISPR/CAS9 FOR CANCER IMMUNOTHERAPY by Tipanee, Jaitip, Samara-Kuko, Ermira, Gevaert, Thierry, Chuah, Marinee K., VandenDriessche, Thierry

“…Allogeneic CD19-specific chimeric antigen receptor (CAR) T cells with inactivated donor T cell receptor (TCR) expression can be used as an ‘off-the-shelf’…”
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Meta-analysis of gene expression profiles identifies differential biomarkers for hepatocellular carcinoma and cholangiocarcinoma by Likhitrattanapisal, Somsak, Tipanee, Jaitip, Janvilisri, Tavan

“…Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are the members of hepatobiliary diseases. Both types of cancer often exert high levels of…”
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Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes by Dastidar, Sumitava, Majumdar, Debanjana, Tipanee, Jaitip, Singh, Kshitiz, Klein, Arnaud F., Furling, Denis, Chuah, Marinee K., VandenDriessche, Thierry

“…CTG repeat expansion (CTGexp) is associated with aberrant alternate splicing that contributes to cardiac dysfunction in myotonic dystrophy type 1 (DM1)…”
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