Search Results - "Tintle, Nathan L"

The Omega-3 Index and relative risk for coronary heart disease mortality: Estimation from 10 cohort studies by Harris, William S, Del Gobbo, Liana, Tintle, Nathan L

“…Abstract Background and aims A recent 19-cohort meta-analysis examined the relationships between biomarkers of omega-3 fatty acids and risk for coronary heart…”
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Association between Omega-3 Index and Hyperglycemia Depending on Body Mass Index among Adults in the United States by Jo, Sunyoung, Harris, William S, Tintle, Nathan L, Park, Yongsoon

“…There is inconsistency regarding the association between long-chain -3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA; 20:5n3) and…”
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A genome-wide association study of red-blood cell fatty acids and ratios incorporating dietary covariates: Framingham Heart Study Offspring Cohort by Kalsbeek, Anya, Veenstra, Jenna, Westra, Jason, Disselkoen, Craig, Koch, Kristin, McKenzie, Katelyn A, O'Bott, Jacob, Vander Woude, Jason, Fischer, Karen, Shearer, Greg C, Harris, William S, Tintle, Nathan L

“…Recent analyses have suggested a strong heritable component to circulating fatty acid (FA) levels; however, only a limited number of genes have been identified…”
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Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey by Xu, Anna, Hilton, Elizabeth, Arkema, Riley, Tintle, Nathan L, Helming, Luralyn M

“…Chronic pain can pose a serious challenge in everyday life for many individuals globally, especially in developing countries, but studies explicitly exploring…”
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Assessing methods for assigning SNPs to genes in gene-based tests of association using common variants by Petersen, Ashley, Alvarez, Carolina, DeClaire, Scott, Tintle, Nathan L

“…Gene-based tests of association are frequently applied to common SNPs (MAF>5%) as an alternative to single-marker tests. In this analysis we conduct a variety…”
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The Associations between Self-Reported Exposure to the Chernobyl Nuclear Disaster Zone and Mental Health Disorders in Ukraine by Bolt, Matthew A, Helming, Luralyn M, Tintle, Nathan L

“…In 1986, Reactor 4 of the Chernobyl nuclear power plant near Pripyat, Ukraine exploded, releasing highly-radioactive materials into the surrounding…”
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Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study by Harris, William S, Tintle, Nathan L, Ramachandran, Vasan S

“…The prognostic value of erythrocyte levels of n-6 fatty acids (FAs) for total mortality and cardiovascular disease (CVD) outcomes remains an open question. We…”
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The Effects of Omega-3 Supplementation on the Omega-3 Index and Quality of Life and Pain Scores in Dogs by Carlisle, Carolina, Metzger, Brandon T, Tintle, Nathan L, Polley, Kristine, Jackson, Kristina H, Le Brun-Blashka, Sara, Griffiths, Jody, Harris, William S

“…This study in dogs had two objectives: first, to determine whether a daily supplement of marine omega-3 (EPA and DHA) would (1) increase red blood cell EPA +…”
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Association of the Omega-3 Index with Incident Prostate Cancer with Updated Meta-Analysis: The Cooper Center Longitudinal Study by Farrell, Stephen W, DeFina, Laura F, Tintle, Nathan L, Leonard, David, Cooper, Kenneth H, Barlow, Carolyn E, Haskell, William L, Pavlovic, Andjelka, Harris, William S

“…The association between long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA) and prostate cancer (PC) remains unclear. We compared incident PC rates as a…”
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Mentoring Undergraduate Research in Statistics: Reaping the Benefits and Overcoming the Barriers by Nolan, Joseph R., McConville, Kelly S., Addona, Vittorio, Tintle, Nathan L., Pearl, Dennis K.

“…Undergraduate research experiences (UREs), whether within the context of a mentor-mentee experience or a classroom framework, represent an excellent…”
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Assessing the impact of differential genotyping errors on rare variant tests of association by Mayer-Jochimsen, Morgan, Fast, Shannon, Tintle, Nathan L

“…Genotyping errors are well-known to impact the power and type I error rate in single marker tests of association. Genotyping errors that happen according to…”
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Investigating Rurality as a Risk Factor for State and Trait Hopelessness in Hospitalized Patients With Ischemic Heart Disease by Bomgaars, Deb, Jensen, Gwenneth A, White, Lynn L, Van De Griend, Kristin M, Visser, Angela K, Goodyke, Madison P, Luong, Anna, Tintle, Nathan L, Dunn, Susan L

“…Background Rurality and hopelessness are each associated with increased mortality in adults with ischemic heart disease (IHD), yet there is no known research…”
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Blood omega-3 fatty acids and death from COVID-19: A pilot study by Asher, Arash, Tintle, Nathan L., Myers, Michael, Lockshon, Laura, Bacareza, Heribert, Harris, William S.

“…•Nutrition-based interventions to reduce COVID-19 morbidity/mortality are needed.•The Omega-3 Index (O3I) was measured in banked blood from 100 COVID-19…”
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Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts by Yang, Chaojie, Veenstra, Jenna, Bartz, Traci M., Pahl, Matthew C., Hallmark, Brian, Chen, Yii-Der Ida, Westra, Jason, Steffen, Lyn M., Brown, Christopher D., Siscovick, David, Tsai, Michael Y., Wood, Alexis C., Rich, Stephen S., Smith, Caren E., O’Connor, Timothy D., Mozaffarian, Dariush, Grant, Struan F. A., Chilton, Floyd H., Tintle, Nathan L., Lemaitre, Rozenn N., Manichaikul, Ani

“…Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) play critical roles in human health. Prior genome-wide association studies (GWAS) of n-3…”
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Evaluating the consistency of gene sets used in the analysis of bacterial gene expression data by Tintle, Nathan L, Sitarik, Alexandra, Boerema, Benjamin, Young, Kylie, Best, Aaron A, Dejongh, Matthew

“…Statistical analyses of whole genome expression data require functional information about genes in order to yield meaningful biological conclusions. The Gene…”
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Epigenome wide association study of SNP-CpG interactions on changes in triglyceride levels after pharmaceutical intervention: a GAW20 analysis by Veenstra, Jenna, Kalsbeek, Anya, Koster, Karissa, Ryder, Nathan, Bos, Abbey, Huisman, Jordan, VanderBerg, Lucas, VanderWoude, Jason, Tintle, Nathan L

“…In the search for an understanding of how genetic variation contributes to the heritability of common human disease, the potential role of epigenetic factors,…”
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Association between blood N-3 fatty acid levels and the risk of coronavirus disease 2019 in the UK Biobank by Harris, William S., Tintle, Nathan L., Sathyanarayanan, Swaminathan Perinkulam, Westra, Jason

“…The role of nutritional status and the risk of contracting and/or experiencing adverse outcomes from severe acute respiratory syndrome coronavirus 2…”
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Computing and applying atomic regulons to understand gene expression and regulation by Faria, J., Davis, James J., Edirisinghe, Janaka N., Taylor, Ronald C., Weisenhorn, Pamela, Olson, Robert D., Stevens, Rick L., Rocha, Miguel, Rocha, Isabel, Best, Aaron A., DeJongh, Matthew, Tintle, Nathan L., Parrello, Bruce, Overbeek, Ross, Henry, Christopher S.

“…The Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb.2016.01819/full#supplementary-material…”
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Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study by Harris, William S., Tintle, Nathan L., Etherton, Mark R., Vasan, Ramachandran S.

“…The extent to which omega-3 fatty acid status is related to risk for death from any cause and for incident cardiovascular disease (CVD) remains controversial…”
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Evaluating the performance of gene-based tests of genetic association when testing for association between methylation and change in triglyceride levels at GAW20 by Vander Woude, Jason, Huisman, Jordan, Vander Berg, Lucas, Veenstra, Jenna, Bos, Abbey, Kalsbeek, Anya, Koster, Karissa, Ryder, Nathan, Tintle, Nathan L

“…Although methylation data continues to rise in popularity, much is still unknown about how to best analyze methylation data in genome-wide analysis contexts…”
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