Search Results - "Tingle, Ryan"

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design by Irimia, Adriana, Serra, Andreia M, Sarkar, Anita, Jacak, Ronald, Kalyuzhniy, Oleksandr, Sok, Devin, Saye-Francisco, Karen L, Schiffner, Torben, Tingle, Ryan, Kubitz, Michael, Adachi, Yumiko, Stanfield, Robyn L, Deller, Marc C, Burton, Dennis R, Schief, William R, Wilson, Ian A

“…Among broadly neutralizing antibodies to HIV, 10E8 exhibits greater neutralizing breadth than most. Consequently, this antibody is the focus of…”
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Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign by Gaj, Thomas, Sirk, Shannon J, Tingle, Ryan D, Mercer, Andrew C, Wallen, Mark C, Barbas, Carlos F

“…Despite recent advances in genome engineering made possible by the emergence of site-specific endonucleases, there remains a need for tools capable of…”
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Vaccination induces HIV broadly neutralizing antibody precursors in humans by Leggat, David J, Cohen, Kristen W, Willis, Jordan R, Fulp, William J, deCamp, Allan C, Kalyuzhniy, Oleksandr, Cottrell, Christopher A, Menis, Sergey, Finak, Greg, Ballweber-Fleming, Lamar, Srikanth, Abhinaya, Plyler, Jason R, Schiffner, Torben, Liguori, Alessia, Rahaman, Farhad, Lombardo, Angela, Philiponis, Vincent, Whaley, Rachael E, Seese, Aaron, Brand, Joshua, Ruppel, Alexis M, Hoyland, Wesley, Yates, Nicole L, Williams, LaTonya D, Greene, Kelli, Gao, Hongmei, Mahoney, Celia R, Corcoran, Martin M, Cagigi, Alberto, Taylor, Alison, Brown, David M, Ambrozak, David R, Sincomb, Troy, Hu, Xiaozhen, Tingle, Ryan, Georgeson, Erik, Eskandarzadeh, Saman, Alavi, Nushin, Lu, Danny, Mullen, Tina-Marie, Kubitz, Michael, Groschel, Bettina, Maenza, Janine, Kolokythas, Orpheus, Khati, Nadia, Bethony, Jeffrey, Crotty, Shane, Roederer, Mario, Karlsson Hedestam, Gunilla B, Tomaras, Georgia D, Montefiori, David, Diemert, David, Koup, Richard A, Laufer, Dagna S, McElrath, M Juliana, McDermott, Adrian B, Schief, William R

“…Broadly neutralizing antibodies (bnAbs) can protect against HIV infection but have not been induced by human vaccination. A key barrier to bnAb induction is…”
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Validation Of A Wearable Inertial Sensor Unit To Measure Balance And Sway During Postural Tasks: 3404 Board #225 May 29 2:30 PM - 4:00 PM by Avedesian, Jason M., Varre, Mathew Sunil, Tingle, Ryan, Dufek, Janet S.

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Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole, Adachi, Yumiko, Tingle, Ryan, Wu, Lin, Crotty, Shane, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D

“…B‐cell receptor (BCR) knock‐in (KI) mouse models play an important role in vaccine development and fundamental immunological studies. However, the time…”
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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models by Huang, Deli, Abbott, Robert K., Havenar-Daughton, Colin, Skog, Patrick D., Al-Kolla, Rita, Groschel, Bettina, Blane, Tanya R., Menis, Sergey, Tran, Jenny Tuyet, Thinnes, Theresa C., Volpi, Sabrina A., Liguori, Alessia, Schiffner, Torben, Villegas, Sophia M., Kalyuzhniy, Oleksandr, Pintea, Mark, Voss, James E., Phelps, Nicole, Tingle, Ryan, Rodriguez, Alberto R., Martin, Greg, Kupryianov, Sergey, deCamp, Allan, Schief, William R., Nemazee, David, Crotty, Shane

“…Animal models of human antigen-specific B cell receptors (BCRs) generally depend on “inferred germline” sequences, and thus their relationship to authentic…”
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Affinity gaps among B cells in germinal centers drive the selection of MPER precursors by Ray, Rashmi, Schiffner, Torben, Wang, Xuesong, Yan, Yu, Rantalainen, Kimmo, Lee, Chang-Chun David, Parikh, Shivang, Reyes, Raphael A., Dale, Gordon A., Lin, Ying-Cing, Pecetta, Simone, Giguere, Sophie, Swanson, Olivia, Kratochvil, Sven, Melzi, Eleonora, Phung, Ivy, Madungwe, Lisa, Kalyuzhniy, Oleksandr, Warner, John, Weldon, Stephanie R., Tingle, Ryan, Lamperti, Edward, Kirsch, Kathrin H., Phelps, Nicole, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, Nair, Usha, Crotty, Shane, Wilson, Ian A., Schief, William R., Batista, Facundo D.

“…Current prophylactic human immunodeficiency virus 1 (HIV-1) vaccine research aims to elicit broadly neutralizing antibodies (bnAbs). Membrane-proximal external…”
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Vaccination induces broadly neutralizing antibody precursors to HIV gp41 by Schiffner, Torben, Phung, Ivy, Ray, Rashmi, Irimia, Adriana, Tian, Ming, Swanson, Olivia, Lee, Jeong Hyun, Lee, Chang-Chun D., Marina-Zárate, Ester, Cho, So Yeon, Huang, Jiachen, Ozorowski, Gabriel, Skog, Patrick D., Serra, Andreia M., Rantalainen, Kimmo, Allen, Joel D., Baboo, Sabyasachi, Rodriguez, Oscar L., Himansu, Sunny, Zhou, Jianfu, Hurtado, Jonathan, Flynn, Claudia T., McKenney, Katherine, Havenar-Daughton, Colin, Saha, Swati, Shields, Kaitlyn, Schultze, Steven, Smith, Melissa L., Liang, Chi-Hui, Toy, Laura, Pecetta, Simone, Lin, Ying-Cing, Willis, Jordan R., Sesterhenn, Fabian, Kulp, Daniel W., Hu, Xiaozhen, Cottrell, Christopher A., Zhou, Xiaoya, Ruiz, Jennifer, Wang, Xuesong, Nair, Usha, Kirsch, Kathrin H., Cheng, Hwei-Ling, Davis, Jillian, Kalyuzhniy, Oleksandr, Liguori, Alessia, Diedrich, Jolene K., Ngo, Julia T., Lewis, Vanessa, Phelps, Nicole, Tingle, Ryan D., Spencer, Skye, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, Eskandarzadeh, Saman, Elsliger, Marc A., Amara, Rama R., Landais, Elise, Briney, Bryan, Burton, Dennis R., Carnathan, Diane G., Silvestri, Guido, Watson, Corey T., Yates, John R., Paulson, James C., Crispin, Max, Grigoryan, Gevorg, Ward, Andrew B., Sok, Devin, Alt, Frederick W., Wilson, Ian A., Batista, Facundo D., Crotty, Shane, Schief, William R.

“…A key barrier to the development of vaccines that induce broadly neutralizing antibodies (bnAbs) against human immunodeficiency virus (HIV) and other viruses…”
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Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41 by Schiffner, Torben, Phung, Ivy, Ray, Rashmi, Irimia, Adriana, Tian, Ming, Swanson, Olivia, Lee, Jeong Hyun, Lee, Chang-Chun D., Marina-Zárate, Ester, Cho, So Yeon, Huang, Jiachen, Ozorowski, Gabriel, Skog, Patrick D., Serra, Andreia M., Rantalainen, Kimmo, Allen, Joel D., Baboo, Sabyasachi, Rodriguez, Oscar L., Himansu, Sunny, Zhou, Jianfu, Hurtado, Jonathan, Flynn, Claudia T., McKenney, Katherine, Havenar-Daughton, Colin, Saha, Swati, Shields, Kaitlyn, Schultze, Steven, Smith, Melissa L., Liang, Chi-Hui, Toy, Laura, Pecetta, Simone, Lin, Ying-Cing, Willis, Jordan R., Sesterhenn, Fabian, Kulp, Daniel W., Hu, Xiaozhen, Cottrell, Christopher A., Zhou, Xiaoya, Ruiz, Jennifer, Wang, Xuesong, Nair, Usha, Kirsch, Kathrin H., Cheng, Hwei-Ling, Davis, Jillian, Kalyuzhniy, Oleksandr, Liguori, Alessia, Diedrich, Jolene K., Ngo, Julia T., Lewis, Vanessa, Phelps, Nicole, Tingle, Ryan D., Spencer, Skye, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, Eskandarzadeh, Saman, Elsliger, Marc A., Amara, Rama R., Landais, Elise, Briney, Bryan, Burton, Dennis R., Carnathan, Diane G., Silvestri, Guido, Watson, Corey T., Yates, John R., Paulson, James C., Crispin, Max, Grigoryan, Gevorg, Ward, Andrew B., Sok, Devin, Alt, Frederick W., Wilson, Ian A., Batista, Facundo D., Crotty, Shane, Schief, William R.

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mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models by Wang, Xuesong, Cottrell, Christopher A, Hu, Xiaozhen, Ray, Rashmi, Bottermann, Maria, Villavicencio, Paula Maldonado, Yan, Yu, Xie, Zhenfei, Warner, John E, Ellis-Pugh, Jordan Renae, Kalyuzhniy, Oleksandr, Liguori, Alessia, Willis, Jordan R, Menis, Sergey, Rämisch, Sebastian, Eskandarzadeh, Saman, Kubitz, Michael, Tingle, Ryan, Phelps, Nicole, Groschel, Bettina, Himansu, Sunny, Carfi, Andrea, Kirsch, Kathrin H, Weldon, Stephanie R, Nair, Usha, Schief, William R, Batista, Facundo D

“…Germline-targeting (GT) protein immunogens to induce VRC01-class broadly neutralizing antibodies (bnAbs) to the CD4-binding site of the HIV envelope (Env) have…”
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