Search Results - "Ting, Nicholas S.Y"

human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1 by Ting, Nicholas S.Y, Pohorelic, Brant, Yu, Yaping, Lees-Miller, Susan P, Beattie, Tara L

“…Telomere integrity in human cells is maintained by the dynamic interplay between telomerase, telomere associated proteins, and DNA repair proteins. These…”
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hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms by Tsang, Allison R., Wyatt, Haley D.M., Ting, Nicholas S.Y., Beattie, Tara L.

“…Summary Telomerase is a ribonucleoprotein reverse transcriptase (RT) that synthesizes specific DNA repeats, or telomeric DNA, at the ends of chromosomes…”
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Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase by Ting, Nicholas S. Y., Yu, Yaping, Pohorelic, Brant, Lees-Miller, Susan P., Beattie, Tara L.

“…Maintenance of telomere integrity requires the dynamic interplay between telomerase, telomere-associated proteins and DNA repair proteins. These interactions…”
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The DNA double-strand break response pathway: becoming more BRCAish than ever by Ting, Nicholas S.Y., Lee, Wen-Hwa

“…Breast carcinoma is the leading cause of cancer incidence, and second in cancer mortality to lung cancer, in women of the Western hemisphere. Germ line…”
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M Phase-specific Phosphorylation of BRCA2 by Polo-like Kinase 1 Correlates with the Dissociation of the BRCA2-P/CAF Complex by Lin, Horng-Ru, Ting, Nicholas S.Y., Qin, Jun, Lee, Wen-Hwa

“…BRCA2 is a breast tumor susceptibility gene encoding a 390-kDa protein with functions in maintaining genomic stability and cell cycle progression. Evidence has…”
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DNA-dependent Protein Kinase Interacts with Antigen Receptor Response Element Binding Proteins NF90 and NF45 by Ting, Nicholas S.Y., Kao, Peter N., Chan, Doug W., Lintott, Lauri G., Lees-Miller, Susan P.

“…The DNA-dependent protein kinase (DNA-PK) is composed of a large catalytic subunit of approximately 470 kDa (DNA-PKcs) and the DNA-binding protein, Ku. Absence…”
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Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta by Chan, D W, Mody, C H, Ting, N S, Lees-Miller, S P

“…The double-stranded DNA-activated protein kinase (DNA-PK) is a serine-threonine protein kinase that is composed of a large catalytic subunit (p350) and a…”
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Protein-DNA Complexes Containing DNA-Dependent Protein Kinase in Crude Extracts from Human and Rodent Cells by Nicholas S. Y. Ting, Chan, Doug W., Lintott, Lauri G., Allalunis-Turner, Joan, Lees-Miller, Susan P.

“…The DNA-dependent protein kinase (DNA-PK) is composed of a large catalytic subunit (DNA-PKcs) and a DNA-binding protein, Ku. Cells lacking DNA-PK activity are…”
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