Search Results - "Ting, Kenneth K Y"

Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway by Ting, Kenneth K. Y., Yu, Pei, Dow, Riley, Ibrahim, Hisham, Karim, Saraf, Polenz, Chanele K., Winer, Daniel A., Woo, Minna, Jongstra-Bilen, Jenny, Cybulsky, Myron I.

“…Lipid accumulation in macrophages (Mφs) is a hallmark of atherosclerosis. Yet, how lipid loading modulates Mφ inflammatory responses remains unclear. We…”
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Fructose-induced metabolic reprogramming of cancer cells by Ting, Kenneth K Y

“…Excess dietary fructose consumption has been long proposed as a culprit for the world-wide increase of incidence in metabolic disorders and cancer within the…”
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Fructose overconsumption-induced reprogramming of microglia metabolism and function by Ting, Kenneth K Y

“…The overconsumption of dietary fructose has been proposed as a major culprit for the rise of many metabolic diseases in recent years, yet the relationship…”
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Revisiting the role of hypoxia-inducible factors and nuclear factor erythroid 2-related factor 2 in regulating macrophage inflammation and metabolism by Ting, Kenneth K Y

“…The recent birth of the immunometabolism field has comprehensively demonstrated how the rewiring of intracellular metabolism is critical for supporting the…”
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The multi-faceted role of NADPH in regulating inflammation in activated myeloid cells by Ting, Kenneth K Y, Jongstra-Bilen, Jenny, Cybulsky, Myron I

“…Recent advances in the immunometabolism field have demonstrated the importance of metabolites in fine-tuning the inflammatory responses in myeloid cells…”
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John Yudkin's hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease by Ting, Kenneth K Y

“…To date, the risk of developing atherosclerosis has extended beyond Western countries and now affecting individuals from various ethnic backgrounds and age…”
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Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway by Ting, Kenneth K Y, Yu, Pei, Dow, Riley, Floro, Eric, Ibrahim, Hisham, Scipione, Corey A, Hyduk, Sharon J, Polenz, Chanele K, Zaslaver, Olga, Karmaus, Peer W F, Fessler, Michael B, Röst, Hannes L, Ohh, Michael, Tsai, Sue, Winer, Daniel A, Woo, Minna, Rocheleau, Jonathan, Jongstra-Bilen, Jenny, Cybulsky, Myron I

“…Lipid accumulation in macrophages (Mφs) is a hallmark of atherosclerosis, yet how lipid accumulation affects inflammatory responses through rewiring of Mφ…”
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Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation by Ting, Kenneth K Y, Yu, Pei, Iyayi, Mudia, Dow, Riley, Hyduk, Sharon J, Floro, Eric, Ibrahim, Hisham, Karim, Saraf, Polenz, Chanele K, Winer, Daniel A, Woo, Minna, Rocheleau, Jonathan, Jongstra-Bilen, Jenny, Cybulsky, Myron I

“…The accumulation of lipid and the formation of macrophage foam cells is a hallmark of atherosclerosis, a chronic inflammatory disease. To better understand the…”
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