Search Results - "Timpe, Leslie"

An online Google Colab project for exploring the SARS CoV‐2 genome and mRNA vaccines by Timpe, Leslie C.

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Over‐Expression of RNA Processing, Heat Shock, and DNA Repair Proteins in Breast Tumor Compared to Normal Tissue by Yen, Ten‐Yang, Wong, Richard, Pizzo, Donald, Thein, Moe, Macher, Bruce A., Timpe, Leslie C.

“…This study identifies the main changes in protein expression in human breast tumors compared to normal breast tissue. Malignant tumors (32) and normal breast…”
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Glycoproteins in Claudin-Low Breast Cancer Cell Lines Have a Unique Expression Profile by Yen, Ten-Yang, Bowen, Spencer, Yen, Roger, Piryatinska, Alexandra, Macher, Bruce A, Timpe, Leslie C

“…Claudin proteins are components of epithelial tight junctions; a subtype of breast cancer has been defined by the reduced expression of mRNA for claudins and…”
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Glycoprotein Profiles of Human Breast Cells Demonstrate a Clear Clustering of Normal/Benign versus Malignant Cell Lines and Basal versus Luminal Cell Lines by Yen, Ten-Yang, Macher, Bruce A, McDonald, Claudia A, Alleyne-Chin, Chris, Timpe, Leslie C

“…Gene expression profiling has defined molecular subtypes of breast cancer including those identified as luminal and basal. To determine if glycoproteins…”
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Using a cell line breast cancer progression system to identify biomarker candidates by Yen, Ten-Yang, Haste, Nicole, Timpe, Leslie C., Litsakos-Cheung, Christina, Yen, Roger, Macher, Bruce A.

“…Secreted and plasma membrane glycoproteins are considered excellent candidates for disease biomarkers. Herein we describe the identification of secreted and…”
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Systemic alteration of cell-surface and secreted glycoprotein expression in malignant breast cancer cell lines by Timpe, Leslie C, Yen, Roger, Haste, Nicole V, Litsakos-Cheung, Christina, Yen, Ten-Yang, Macher, Bruce A

“…Breast cancer cell lines express fewer transmembrane and secreted glycoproteins than nonmalignant ones. The objective of these experiments was to characterize…”
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frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance by Kolodziej, Peter A, Timpe, Leslie C, Mitchell, Kevin J, Fried, Sharon R, Goodman, Corey S, Jan, Lily Yeh, Jan, Yuh Nung

“…We have identified a Drosophila member of the deleted in colorectal cancer (DCC) gene family. The frazzled gene encodes transmembrane proteins that contain…”
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Overcoming challenges and opening new opportunities in glycoproteomics by Yen, Ten-Yang, Dutta, Sucharita M, Litsakos-Cheung, Christina, Corona, Alejandro A, Timpe, Leslie C, Macher, Bruce A

“…Glycoproteomics has emerged as a prime area of interest within the field of proteomics because glycoproteins have been shown to function as biomarkers for…”
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Identification of an inward rectifier potassium channel gene expressed in mouse cortical astrocytes by Li, Luyi, Head, Valerie, Timpe, Leslie C.

“…These experiments identify an inward rectifier K+ (Kir) channel expressed in mouse cortical and white matter astrocytes at the molecular level. Messenger RNA…”
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An online G oogle C olab project for exploring the SARS CoV ‐2 genome and mRNA vaccines by Timpe, Leslie C.

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Unitary Conductance Variation in Kir2.1 and in Cardiac Inward Rectifier Potassium Channels by Picones, Arturo, Keung, Edmund, Timpe, Leslie C.

“…Kir2.1 (IRK1) is the complementary DNA for a component of a cardiac inwardly rectifying potassium channel. When Kir2.1 is expressed in Xenopus oocytes or human…”
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Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence by Papazian, Diane M, Timpe, Leslie C, Jan, Yuh Nung, Jan, Lily Y

“…Voltage-dependent potassium, sodium and calcium ion channels may share a common mechanism of activation, in which the conserved S4 sequence acts as the primary…”
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A possible billion-year-old holozoan with differentiated multicellularity by Strother, Paul K., Brasier, Martin D., Wacey, David, Timpe, Leslie, Saunders, Martin, Wellman, Charles H.

“…Sediments of the Torridonian sequence of the Northwest Scottish Highlands contain a wide array of microfossils, documenting life in a non-marine setting a…”
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Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes by Timpe, Leslie C, Schwarz, Thomas L, Tempel, Bruce L, Papazian, Diane M, Jan, Yuh Nung, Jan, Lily Y

“…The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA…”
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Collectively Improving Our Teaching: Attempting Biology Department-Wide Professional Development in Scientific Teaching by Owens, Melinda T, Trujillo, Gloriana, Seidel, Shannon B, Harrison, Colin D, Farrar, Katherine M, Benton, Hilary P, Blair, J. R, Boyer, Katharyn E, Breckler, Jennifer L, Burrus, Laura W, Byrd, Dana T, Caporale, Natalia, Carpenter, Edward J, Chan, Yee-Hung M, Chen, Joseph C, Chen, Lily, Chen, Linda H, Chu, Diana S, Cochlan, William P, Crook, Robyn J, Crow, Karen D, de la Torre, José R, Denetclaw, Wilfred F, Dowdy, Lynne M, Franklin, Darleen, Fuse, Megumi, Goldman, Michael A, Govindan, Brinda, Green, Michael, Harris, Holly E, He, Zheng-Hui, Ingalls, Stephen B, Ingmire, Peter, Johnson, Amber R. B, Knight, Jonathan D, LeBuhn, Gretchen, Light, Terrye L, Low, Candace, Lund, Lance, Márquez-Magaña, Leticia M, Miller-Sims, Vanessa C, Moffatt, Christopher A, Murdock, Heather, Nusse, Gloria L, Parker, V. Thomas, Pasion, Sally G, Patterson, Robert, Pennings, Pleuni S, Ramirez, Julio C, Ramirez, Robert M, Riggs, Blake, Rohlfs, Rori V, Romeo, Joseph M, Rothman, Barry S, Roy, Scott W, Russo-Tait, Tatiane, Sehgal, Ravinder N. M, Simonin, Kevin A, Spicer, Greg S, Stillman, Jonathon H, Swei, Andrea, Timpe, Leslie C, Vredenburg, Vance T, Weinstein, Steven L, Zink, Andrew G, Kelley, Loretta A, Domingo, Carmen R, Tanner, Kimberly D

“…Many efforts to improve science teaching in higher education focus on a few faculty members at an institution at a time, with limited published evidence on…”
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Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes by Timpe, L C, Jan, Y N, Jan, L Y

“…The Shaker gene encodes the A-channel of larval and pupal muscle, or one or more of its subunits. Alternative splicing produces messages for several different…”
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Modulation of a voltage-activated potassium channel by peptide growth factor receptors by Timpe, LC, Fantl, WJ

“…Regulation of the activity of a cloned component of a voltage-activated K+ channel, Kv1.5, was studied by expressing the K+ channel and receptors for…”
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Alternatively spliced forms of the cGMP-gated channel in human keratinocytes by Oda, Yuko, Timpe, Leslie C, McKenzie, Roderick C, Sauder, Daniel N, Largman, Corey, Mauro, Theodora

“…Alternatively spliced forms of the α subunit of the cGMP-gated channel have been cloned from human keratinocytes. One form encodes a complete channel which is…”
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Least Squares Methods for Equidistant Tree Reconstruction by Fahey, Conor, Hosten, Serkan, Krieger, Nathan, Timpe, Leslie

“…UPGMA is a heuristic method identifying the least squares equidistant phylogenetic tree given empirical distance data among $n$ taxa. We study this classic…”
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Cyclic nucleotide-gated cation channel expression in embryonic chick brain by Timpe, Leslie C., Jin, Kun Lin, Puelles, Luis, Rubenstein, John L.R.

“…Cyclic nucleotide-gated cation channels mediate sensory transduction in vertebrate photoreceptors and olfactory epithelium. These channels are also present in…”
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