Search Results - "Timothy E. Hotaling"

Stability and Interactions of Recombinant Human Nerve Growth Factor in Different Biological Matrices: In Vitro and In Vivo Studies by Cindy B. Nguyen, Éva Szönyi, Michael D. Sadick, Timothy E. Hotaling, Jose-Luis Mendoza-Ramirez, Enrique Escandón

“…The purpose of this investigation was to characterize the stability, activity, and interactions of recombinant human nerve growth factor (rhNGF) in various…”
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Abstract 42: Preclinical development of a duocarmycin-based antibody-drug conjugate targeting B7-H3 for solid cancer by Son, Thomas, Scribner, Juniper A., Hooley, Jeff, Chiechi, Michael, Li, Pam, Hotaling, Timothy E., Costa, Anushka De, Chen, Yan, Chen, Francine, Barat, Bhaswati, Ciccarone, Valentina, Gaynutdinov, Timur, Tamura, James, Koenig, Scott, Johnson, Syd, Moore, Paul A., Bonvini, Ezio, Loo, Deryk

“…Introduction: B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers. B7-H3 overexpression has been…”
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Abstract 38: Target validation, antibody discovery and preclinical data supporting ADAM9 as an antibody-drug conjugate therapeutic target for solid tumors by Scribner, Juniper A., Barat, Bhaswati, Hicks, Stuart W., Yoder, Nicholas C., Son, Thomas, Widjaja, Lusiana, Diedrich, Gundo, Gorlatov, Sergey, Hooley, Jeff, Easton, Ann, Lung, Peter, Costa, Anushka De, Chen, Francine, Chiechi, Michael, Li, Pam, Licea, Monica, Hotaling, Timothy E., Spliedt, Michael, Ciccarone, Valentina, Gantt, Nadia, Tamura, James, Fuller, Megan E., McShea, Molly, Koenig, Scott, Johnson, Syd, Moore, Paul A., Bonvini, Ezio, Loo, Deryk

“…Introduction: A target-unbiased approach based on intact cell immunizations with fetal progenitor cells and cancer stem cells, followed by an…”
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Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys by Fox, J A, Hotaling, T E, Struble, C, Ruppel, J, Bates, D J, Schoenhoff, M B

“…A humanized antihuman IgE antibody, rhuMAb-E25, was designed to form complexes with free IgE, blocking its interaction with mast cells and basophils and…”
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