Search Results - "Timoshchenko, Roman G."

G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis by Billard, Matthew J, Fitzhugh, David J, Parker, Joel S, Brozowski, Jaime M, McGinnis, Marcus W, Timoshchenko, Roman G, Serafin, D Stephen, Lininger, Ruth, Klauber-Demore, Nancy, Sahagian, Gary, Truong, Young K, Sassano, Maria F, Serody, Jonathan S, Tarrant, Teresa K

“…Triple negative breast cancer (TNBC) is a heterogeneous disease that has a poor prognosis and limited treatment options. Chemokine receptor interactions are…”
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G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses by Tarrant, Teresa K., Billard, Matthew J., Timoshchenko, Roman G., McGinnis, Marcus W., Serafin, D. Stephen, Foreman, Oded, Esserman, Denise A., Chao, Nelson J., Lento, William E., Lee, David M., Patel, Dhavalkumar, Siderovski, David P.

“…GRK3−/− mice exhibit impaired CXCL12/CXCR4 responses, myelokathexis and hypogammaglobulinemia, as in WHIM syndrome, and are protected in inflammatory arthritis…”
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G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation by Brozowski, Jaime M, Timoshchenko, Roman G, Serafin, D Stephen, Allyn, Brittney, Koontz, Jessica, Rabjohns, Emily M, Rampersad, Rishi R, Ren, Yinshi, Eudy, Amanda M, Harris, Taylor F, Abraham, David, Mattox, Daniel, Rubin, Clinton T, Hilton, Matthew J, Rubin, Janet, Allbritton, Nancy L, Billard, Matthew J, Tarrant, Teresa K

“…The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the…”
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Roles of chemokines CCL2 and CCL5 in the pharmacokinetics of PEGylated liposomal doxorubicin in vivo and in patients with recurrent epithelial ovarian cancer by Song, Gina, PhD, Tarrant, Teresa K., MD, White, Taylor F., PharmD, Barrow, David A., PhD, Santos, Charlene M., RLATG, Timoshchenko, Roman G., BS, Hanna, Suzan K., BS, Ramanathan, Ramesh K., MD, Lee, Craig R., PhD, Bae-Jump, Victoria L., MD, Gehrig, Paola A., MD, Zamboni, William C., PhD

“…Abstract Nanoparticles (NPs) are cleared by monocytes and macrophages. Chemokines CCL2 and CCL5 are key mediators for recruitment of these immune cells into…”
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Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages by Serafin, D. Stephen, Allyn, Brittney, Sassano, Maria F., Timoshchenko, Roman G., Mattox, Daniel, Brozowski, Jaime M., Siderovski, David P., Truong, Young K., Esserman, Denise, Tarrant, Teresa K., Billard, Matthew J.

“…•A model for CMKLR1 receptor regulation on inflammatory macrophages is proposed.•GRK6 helps recruit β-arrestin 2 to CMKLR1 after chemerin stimulation.•CMKLR1…”
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Decreased Th17 and antigen-specific humoral responses in CX3CR1-deficient mice in the collagen-induced arthritis model by Tarrant, Teresa K., Liu, Peng, Rampersad, Rishi R., Esserman, Denise, Rothlein, Lisa R., Timoshchenko, Roman G., McGinnis, Marcus W., Fitzhugh, David J., Patel, Dhavalkumar D., Fong, Alan M.

“…Objective CX3CR1 is a chemokine receptor that uniquely binds to its ligand fractalkine (CX3CL1) and has been shown to be important in inflammatory arthritis…”
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G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis by Giguère, Patrick M., Billard, Matthew J., Laroche, Geneviève, Buckley, Brian K., Timoshchenko, Roman G., McGinnis, Marcus W., Esserman, Denise, Foreman, Oded, Liu, Peng, Siderovski, David P., Tarrant, Teresa K.

“…► GPSM3 is highly expressed in mature monocytes. ► GPSM3-deficient monocytes have decreased chemotaxis to CCL2, CX3CL1, and chemerin. ► GPSM3-deficient THP-1…”
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Interrogating Genetic Susceptibility Loci in CVID and Autoimmunity by Yang, Luanna, Shah, Shaili N., MD, Serafin, D Stephen, Timoshchenko, Roman G, Scotland, Paula, Richards, Kristy, Billard, Matthew J, Lugar, Patricia L., MD, MS, Tarrant, Teresa K., MD, FAAAAI

“…[...]we hypothesized that possessing the allele may correlate with decreased autoimmunity in CVID…”
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Cellular Targeting in Autoimmunity by Rogers, Jennifer L., Serafin, Donald S., Timoshchenko, Roman G., Tarrant, Teresa K.

“…Many biologic agents that were first approved for the treatment of malignancies are now being actively investigated and used in a variety of autoimmune…”
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Decreased Th17 and antigen‐specific humoral responses in CX 3 CR1‐deficient mice in the collagen‐induced arthritis model by Tarrant, Teresa K., Liu, Peng, Rampersad, Rishi R., Esserman, Denise, Rothlein, Lisa R., Timoshchenko, Roman G., McGinnis, Marcus W., Fitzhugh, David J., Patel, Dhavalkumar D., Fong, Alan M.

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Decreased Th17 and antigen-specific humoral responses in CX₃ CR1-deficient mice in the collagen-induced arthritis model by Tarrant, Teresa K, Liu, Peng, Rampersad, Rishi R, Esserman, Denise, Rothlein, Lisa R, Timoshchenko, Roman G, McGinnis, Marcus W, Fitzhugh, David J, Patel, Dhavalkumar D, Fong, Alan M

“…CX(3) CR1 is a chemokine receptor that uniquely binds to its ligand fractalkine (CX(3) CL1) and has been shown to be important in inflammatory arthritis…”
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CX3CR1 deficient mice have decreased Th17 and antigen-specific humoral responses in the collagen induced arthritis (CIA) model by Tarrant, Teresa K., Liu, Peng, Rampersad, Rishi R., Esserman, Denise, Rothlein, Lisa R., Timoshchenko, Roman G, McGinnis, Marcus W., Fitzhugh, David J, Patel, Dhavalkumar D., Fong, Alan M.

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