Search Results - "Timoneda, Joaquín"
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Vitamin A Deficiency and the Lung
Published in Nutrients (21-08-2018)“…Vitamin A (all- -retinol) is a fat-soluble micronutrient which together with its natural derivatives and synthetic analogues constitutes the group of…”
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Vitamin A Status Modulates Epithelial Mesenchymal Transition in the Lung: The Role of Furin
Published in Nutrients (15-04-2024)“…Vitamin A deficiency (VAD) induced TGF-β hyperactivation and reduced expression of cell adhesion proteins in the lung, suggesting that the disruption of…”
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Vitamin a deficiency and alterations in the extracellular matrix
Published in Nutrients (10-11-2014)“…Vitamin A or retinol which is the natural precursor of several biologically active metabolites can be considered the most multifunctional vitamin in mammals…”
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Vitamin A deficiency alters rat lung alveolar basement membrane Reversibility by retinoic acid
Published in The Journal of nutritional biochemistry (01-03-2010)“…Vitamin A is essential for lung development and pulmonary cell differentiation and its deficiency results in alterations of lung structure and function…”
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Vitamin A deficiency disturbs collagen IV and laminin composition and decreases matrix metalloproteinase concentrations in rat lung. Partial reversibility by retinoic acid
Published in The Journal of nutritional biochemistry (2013)“…Vitamin A is essential for lung development and pulmonary cell differentiation. Its deficiency leads to altered lung structure and function and to basement…”
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Vitamin A deficiency increases protein catabolism and induces urea cycle enzymes in rats
Published in The Journal of nutrition (01-04-2010)“…Chronic vitamin A deficiency induces a substantial delay in the rates of weight and height gain in both humans and experimental animals. This effect has been…”
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Endocytosis in Cultured Neurons Is Altered by Chronic Alcohol Exposure
Published in Toxicological sciences (01-05-2010)“…Endocytosis is required for many cellular pivotal processes, including membrane recycling, nutrient uptake, and signal transduction. This complex process is…”
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Polyphosphoinositide Metabolism and Golgi Complex Morphology in Hippocampal Neurons in Primary Culture is Altered by Chronic Ethanol Exposure
Published in Alcohol and alcoholism (Oxford) (2013)“…Ethanol affects not only the cytoskeletal organization and activity, but also intracellular trafficking in neurons in the primary culture. Polyphosphoinositide…”
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New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation
Published in Chemistry : a European journal (02-05-2011)“…Fluor‐in or out? Based on β,β‐difluorinated cycloaliphatic amino acids, a library of new dipeptide nitriles was evaluated as human cathepsin inhibitors. The…”
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Vitamin A deficiency alters the structure and collagen IV composition of rat renal basement membranes
Published in The Journal of nutrition (01-04-2005)“…Retinoids can modulate the expression of extracellular matrix (ECM) proteins with variable results depending on other contributing factors. Because changes in…”
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Effects of vitamin A deficiency on mitochondrial function in rat liver and heart
Published in British journal of nutrition (01-12-2000)“…The aim of this study was to investigate comparative effects of vitamin A deficiency on respiratory activity and structural integrity in liver and heart…”
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Different adhesins for type IV collagen on Candida albicans: identification of a lectin-like adhesin recognizing the 7S(IV) domain
Published in Microbiology (Society for General Microbiology) (01-07-2001)“…Secció Departamental de Bioquímica i Biologia Molecular, Facultat de Farmacia, Universitat de Valencia, Avda Vicent A. Estellés, s/n, 46100-Burjassot…”
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Chronic Alcohol Alters Dendritic Spine Development in Neurons in Primary Culture
Published in Neurotoxicity research (01-11-2013)“…Dendritic spines are specialised membrane protrusions of neuronal dendrites that receive the majority of excitatory synaptic inputs. Abnormal changes in their…”
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Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen
Published in The Journal of biological chemistry (15-08-1991)“…The noncollagenous (NC1) domain hexamer of glomerular basement membrane (GBM) collagen is composed of a multiplicity of monomeric and dimeric subunits, and…”
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Unusual dissociative behavior of the noncollagenous domain (hexamer) of basement membrane collagen during electrophoresis and chromatofocusing
Published in Connective tissue research (1990)“…The noncollagenous domain of basement membrane collagen exists as a hexamer upon excision with bacterial collagenase. Two hexamer subtypes, differing in…”
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Modification of the catalytic function of the mitochondrial cytochrome b-c1 complex by dicyclohexylcarbodiimide
Published in Biochimica et biophysica acta (30-11-1983)“…N,N'-Dicyclohexylcarbodiimide (DCCD) induces a complex set of effects on the succinate-cytochrome c span of the mitochondrial respiratory chain. At…”
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