Search Results - "Timms, Emma"

Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in Arabidopsis by Mur, Luis A.J, Aubry, Sylvain, Mondhe, Madhav, Kingston-Smith, Alison, Gallagher, Joe, Timms-Taravella, Emma, James, Caron, Papp, Istvan, Hörtensteiner, Stefan, Thomas, Howard, Ougham, Helen

“…The staygreen (SGR) gene encodes a chloroplast-targeted protein which promotes chlorophyll degradation via disruption of light-harvesting complexes (LHCs)…”
Get full text

Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood by Page, Theresa H, Turner, Jeremy J O, Brown, Anthony C, Timms, Emma M, Inglis, Julia J, Brennan, Fionula M, Foxwell, Brian M J, Ray, Keith P, Feldmann, Marc

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase activity and hence PG production. However, the ability of NSAIDs to ameliorate pain and…”
Get full text

Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study by Pearce, Gemma, Holliday, Nikki, Sandhu, Harbinder, Eftekhari, Helen, Bruce, Julie, Timms, Emma, Ablett, Laura, Kavi, Lesley, Simmonds, Jane, Evans, Rebecca, Magee, Paul, Powell, Richard, Keogh, Shane, McGregor, Gordon

“…Abstract Background There is a dearth of research to support the treatment of people with postural tachycardia syndrome (PoTS). Despite expert consensus…”
Get full text

Targeting expression of a fungal ferulic acid esterase to the apoplast, endoplasmic reticulum or golgi can disrupt feruloylation of the growing cell wall and increase the biodegradability of tall fescue (Festuca arundinacea) by Buanafina, Marcia M de O, Langdon, Tim, Hauck, Barbara, Dalton, Sue, Timms-Taravella, Emma, Morris, Phillip

“…In the cell walls of grasses, ferulic acid is esterified to arabinoxylans and undergoes oxidative reactions to form ferulates dimers, trimers and oligomers…”
Get more information

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis by Penninger, Josef M, Kong, Young-Yun, Yoshida, Hiroki, Sarosi, Ildiko, Tan, Hong-Lin, Timms, Emma, Capparelli, Casey, Morony, Sean, Oliveira-dos-Santos, Antonio J, Van, Gwyneth, Itie, Annick, Khoo, Wilson, Wakeham, Andrew, Dunstan, Colin R, Lacey, David L, Mak, Tak W, Boyle, William J

“…The tumour-necrosis-factor-family molecule osteoprotegerin ligand (OPGL; also known as TRANCE, RANKL and ODF) has been identified as a potential osteoclast…”
Get full text

Tumor Necrosis Factor Receptor Family Member RANK Mediates Osteoclast Differentiation and Activation Induced by Osteoprotegerin Ligand by Hsu, Hailing, Lacey, David L., Dunstan, Colin R., Solovyev, Irina, Colombero, Anne, Timms, Emma, Tan, Hong-Lin, Elliott, Gary, Kelley, Michael J., Sarosi, Ildiko, Wang, Ling, Xia, Xing-Zhong, Elliott, Robin, Chiu, Laura, Black, Tabitha, Scully, Sheila, Capparelli, Casey, Morony, Sean, Shimamoto, Grant, Bass, Michael B., Boyle, William J.

“…A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via genomic analysis of a primary…”
Get full text

Transgenic ZmMYB167 Miscanthus sinensis with increased lignin to boost bioenergy generation for the bioeconomy by Bhatia, Rakesh, Timms-Taravella, Emma, Roberts, Luned A, Moron-Garcia, Odin M, Hauck, Barbara, Dalton, Sue, Gallagher, Joe A, Wagner, Moritz, Clifton-Brown, John, Bosch, Maurice

“…Perennial C grasses from the genus Miscanthus are widely regarded as leading and promising dedicated bioenergy crops due to their high biomass accumulation on…”
Get full text

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection by Carter, Michael J., Fish, Matthew, Jennings, Aislinn, Doores, Katie J., Wellman, Paul, Seow, Jeffrey, Acors, Sam, Graham, Carl, Timms, Emma, Kenny, Julia, Neil, Stuart, Malim, Michael H., Tibby, Shane M., Shankar-Hari, Manu

“…Recent reports highlight a new clinical syndrome in children related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1 —multisystem…”
Get full text

The Interferon Regulatory Transcription Factor IRF-1 Controls Positive and Negative Selection of CD8 + Thymocytes by Penninger, Josef M, Sirard, Christian, Mittrücker, Hans-Willi, Chidgey, Anne, Kozieradzki, Ivona, Nghiem, Mai, Hakem, Anne, Kimura, Tohru, Timms, Emma, Boyd, Richard, Taniguchi, Tadatsugu, Matsuyama, Toshifumi, Mak, Tak W

“…Little is known about the molecular mechanisms and transcriptional regulation that govern T cell selection processes and the differentiation of CD4 + and CD8 +…”
Get full text

Effective and Long-Lasting Immunity against the Parasite Leishmania major in CD8-Deficient Mice by HUBER, M, TIMMS, E, MAK, T. W, RÖLLINGHOFF, M, LOHOFF, M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Could Miscanthus replace maize as the preferred substrate for anaerobic digestion in the United Kingdom? Future breeding strategies by Purdy, Sarah J., Maddison, Anne L., Nunn, Christopher P., Winters, Ana, Timms‐Taravella, Emma, Jones, Charlotte M., Clifton‐Brown, John C., Donnison, Iain S., Gallagher, Joe A.

“…Fodder maize is the most commonly used crop for biogas production owing to its high yields, high concentrations of starch and good digestibility. However,…”
Get full text

Shared neutrophil and T cell dysfunction is accompanied by a distinct interferon signature during severe febrile illnesses in children by Patel, Harsita, Carter, Michael J., Jackson, Heather, Powell, Oliver, Fish, Matthew, Terranova-Barberio, Manuela, Spada, Filomena, Petrov, Nedyalko, Wellman, Paul, Darnell, Sarah, Mustafa, Sobia, Todd, Katrina, Bishop, Cynthia, Cohen, Jonathan M., Kenny, Julia, van den Berg, Sarah, Sun, Thomas, Davis, Francesca, Jennings, Aislinn, Timms, Emma, Thomas, Jessica, Nyirendra, Maggie, Nichols, Samuel, Estamiana Elorieta, Leire, D’Souza, Giselle, Wright, Victoria, De, Tisham, Habgood-Coote, Dominic, Ramnarayan, Padmanabhan, Tissières, Pierre, Whittaker, Elizabeth, Herberg, Jethro, Cunnington, Aubrey, Kaforou, Myrsini, Ellis, Richard, Malim, Michael H., Tibby, Shane M., Shankar-Hari, Manu, Levin, Michael

“…Severe febrile illnesses in children encompass life-threatening organ dysfunction caused by diverse pathogens and other severe inflammatory syndromes. A…”
Get full text

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: Does variable inhibition of interleukin‐6 production limit effectiveness in vivo? by Page, Theresa H., Brown, Anthony, Timms, Emma M., Foxwell, Brian M. J., Ray, Keith P.

“…Objective The activity of p38 MAPK regulates lipopolysaccharide (LPS)–stimulated production of key proinflammatory cytokines such as tumor necrosis factor α…”
Get full text

Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4 by Waterhouse, Paul, Penninger, Josef M., Timms, Emma, Wakeham, Andrew, Shahinian, Arda, Lee, Kelvin P., Thompson, Craig B., Griesser, Henrik, Mak, Tak W.

“…The role of the cell-surface molecule CTLA-4 in the regulation of T cell activation has been controversial. Here, lymph nodes and spleens of CTLA-4-deficient…”
Get full text

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin- 2 Receptor β by Suzuki, Haruhiko, Kündig, Thomas M., Furlonger, Caren, Wakeham, Andrew, Timms, Emma, Matsuyama, Toshifumi, Schmits, Rudolf, John J. L. Simard, Ohashi, Pamela S., Griesser, Henrik, Taniguchi, Tadatsugu, Paige, Christopher J., Mak, Tak W.

“…In mice lacking the interleukin-2 receptor β chain (IL-2Rβ), T cells were shown to be spontaneously activated, resulting in exhaustive differentiation of B…”
Get full text

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice by Amakawa, Ryuichi, Hakem, Anne, Kundig, Thomas M, Matsuyama, Toshifumi, Simard, John J.L, Timms, Emma, Wakeham, Andrew, Mittruecker, Hans-Willi, Griesser, Henrik, Takimoto, Hiroaki, Schmits, Rudolf, Shahinian, Arda, Ohashi, Pamela S, Penninger, Josef M, Mak, Tak W

“…CD30 is found on Reed–Sternberg cells of Hodgkin's disease and on a variety of non-Hodgkin's lymphoma cells and is up-regulated on cells after Epstein–Barr…”
Get full text

Nutrient and drought stress: implications for phenology and biomass quality in miscanthus by da Costa, Ricardo M F, Simister, Rachael, Roberts, Luned A, Timms-Taravella, Emma, Cambler, Arthur B, Corke, Fiona M K, Han, Jiwan, Ward, Richard J, Buckeridge, Marcos S, Gomez, Leonardo D, Bosch, Maurice

“…The cultivation of dedicated biomass crops, including miscanthus, on marginal land provides a promising approach to the reduction of dependency on fossil…”
Get full text

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice by Kishihara, K, Penninger, J, Wallace, V A, Kündig, T M, Kawai, K, Wakeham, A, Timms, E, Pfeffer, K, Ohashi, P S, Thomas, M L

“…The transmembrane tyrosine phosphatase CD45 is expressed in multiple isoforms on all nucleated hematopoietic cells, resulting from alternative splicing of…”
Get more information

116 Treatment with Non-steroidal Anti-inflammatory Drugs Increases TNF Production in Rheumatoid Arthritis by Page, Theresa H., Brown, Anthony C., Timms, Emma M., Brennan, Fionula M., Ray, Keith P., Foxwell, Brian M.J.

Get full text

Requirement for Tyrosine Kinase p56$^{lck}$ for Thymic Development of Transgenic γδ T Cells by Penninger, Josef, Kishihara, Kenji, Molina, Thierry, Wallace, Valerie A., Timms, Emma, Hedrick, Stephen M., Mak, Tak W.

“…The Src-related protein tyrosine kinase p56$^{lck}$ is essential for antigen-specific signal transduction and thymic maturation of T cells that have an αβ T…”
Get full text