Search Results - "Timmermans, Vera"
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Characterization of organoid cultured human breast cancer
Published in Breast cancer research : BCR (11-12-2019)“…Organoid cultures are increasingly used to model human cancers experimentally with a view to tailoring personalized medicine and predicting drug responses…”
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Profiling of microRNAs in tumor interstitial fluid of breast tumors – a novel resource to identify biomarkers for prognostic classification and detection of cancer
Published in Molecular oncology (01-02-2017)“…It has been hypothesized based on accumulated data that a class of small noncoding RNAs, termed microRNAs, are key factors in intercellular communication…”
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3
Cryopreservation of ovarian tissue for fertility preservation: no evidence of malignant cell contamination in ovarian tissue from patients with breast cancer
Published in Fertility and sterility (01-05-2011)“…Cryopreserved ovarian cortical biopsies from 51 patients with breast cancer were examined by histologic and immunohistochemical analysis and showed no sign of…”
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Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Published in Proceedings of the National Academy of Sciences - PNAS (17-04-2012)“…The majority of human breast cancers exhibit luminal epithelial differentiation. However, most aggressive behavior, including invasion and purported cancer…”
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FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast
Published in PloS one (12-11-2014)“…Apocrine carcinoma of the breast is a distinctive malignancy with unique morphological and molecular features, generally characterized by being negative for…”
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6
High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy
Published in Molecular oncology (01-10-2015)“…We have previously reported the 2D PAGE-based proteomic profiling of a prospective cohort of 78 triple negative breast cancer (TNBC) patients, and the…”
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Profiling of micro RNA s in tumor interstitial fluid of breast tumors – a novel resource to identify biomarkers for prognostic classification and detection of cancer
Published in Molecular oncology (01-02-2017)“…It has been hypothesized based on accumulated data that a class of small noncoding RNA s, termed micro RNA s, are key factors in intercellular communication…”
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8
Neuroendocrine carcinoma of the breast - a pilot study of a Danish population of 240 breast cancer patients
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-07-2014)“…Neuroendocrine carcinoma of the breast – a very recent diagnosis, which was not recognized by WHO until 2003 – has lately been the subject of increasing…”
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Immunoexpression analysis and prognostic value of BLCAP in breast cancer
Published in PloS one (25-09-2012)“…Bladder Cancer Associated Protein (BLCAP, formerly Bc10), was identified by our laboratory as being down-regulated in bladder cancer with progression. BLCAP is…”
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Proteomic Profiling of Triple-negative Breast Carcinomas in Combination With a Three-tier Orthogonal Technology Approach Identifies Mage-A4 as Potential Therapeutic Target in Estrogen Receptor Negative Breast Cancer
Published in Molecular & cellular proteomics (01-02-2013)“…Breast cancer is a very heterogeneous disease, encompassing several intrinsic subtypes with various morphological and molecular features, natural history and…”
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Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
Published in Oncoimmunology (01-01-2016)“…The tumor microenvironment is composed of many immune cell subpopulations and is an important factor in the malignant progression of neoplasms, particularly…”
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A Marker of Endocrine Receptor-Positive Cells, CEACAM6, Is Shared by Two Major Classes of Breast Cancer
Published in The American journal of pathology (01-04-2014)“…Elucidating the phenotypic evolution of breast cancer through distinct subtypes relies heavily on defining a lineage blueprint of the normal human breast…”
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Epithelial-Stromal Interaction 1 (EPSTI1) Substitutes for Peritumoral Fibroblasts in the Tumor Microenvironment
Published in The American journal of pathology (01-03-2010)“…Tumor cells can activate stroma, yet the implication of this activation in terms of reciprocal induction of gene expression in tumor cells is poorly…”
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A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors
Published in Scientific reports (16-10-2019)“…Human breast cancer is believed to arise in luminal progenitors within the normal breast. A subset of these are double positive (DP) for basal and luminal…”
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15-Prostaglandin Dehydrogenase Expression Alone or in Combination with ACSM1 Defines a Subgroup of the Apocrine Molecular Subtype of Breast Carcinoma
Published in Molecular & cellular proteomics (01-10-2008)“…Established histopathological criteria divide invasive breast carcinomas into defined groups. Ductal of no specific type and lobular are the two major subtypes…”
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Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a well-defined cohort
Published in Molecular oncology (01-06-2009)“…Invasive apocrine carcinomas (IACs), as defined by morphological features, correspond to 0.3–4% of all invasive ductal carcinomas (IDC), and despite the fact…”
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Publisher Correction: A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors
Published in Scientific reports (11-03-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Tissue proteomics of the human mammary gland: Towards an abridged definition of the molecular phenotypes underlying epithelial normalcy
Published in Molecular oncology (01-12-2010)“…Our limited understanding of the biological impact of the whole spectrum of early breast lesions together with a lack of accurate molecular-based risk criteria…”
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Application of digital image analysis on histological images of a murine embryoid body model for monitoring endothelial differentiation
Published in Pathology, research and practice (01-11-2020)“…The in vitro 3D model established from murine pluripotential stem cells (i.e., embryoid bodies (EBs)) is a dynamic model for endothelial differentiation. The…”
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Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis
Published in Proteomics (Weinheim) (01-12-2008)“…Axillary lymph node (ALN) status is currently used as an important clinical indicator of breast cancer prognosis. However, the molecular mechanisms underlying…”
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