Search Results - "Timmerman, Kyle"

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis by Fry, Christopher S, Drummond, Micah J, Glynn, Erin L, Dickinson, Jared M, Gundermann, David M, Timmerman, Kyle L, Walker, Dillon K, Dhanani, Shaheen, Volpi, Elena, Rasmussen, Blake B

“…Sarcopenia, the loss of skeletal muscle mass during aging, increases the risk for falls and dependency. Resistance exercise (RE) training is an effective…”
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Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men by FRY, Christopher S, GLYNN, Erin L, DRUMMOND, Micah J, TIMMERMAN, Kyle L, FUJITA, Satoshi, ABE, Takashi, DHANANI, Shaheen, VOLPI, Elena, RASMUSSEN, Blake B

“…The loss of skeletal muscle mass during aging, sarcopenia, increases the risk for falls and dependence. Resistance exercise (RE) is an effective rehabilitation…”
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Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis by Drummond, Micah J., Fry, Christopher S., Glynn, Erin L., Dreyer, Hans C., Dhanani, Shaheen, Timmerman, Kyle L., Volpi, Elena, Rasmussen, Blake B.

“…Muscle protein synthesis and mTORC1 signalling are concurrently stimulated following muscle contraction in humans. In an effort to determine whether mTORC1…”
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Influence of time of day and intermittent aerobic exercise on vascular endothelial function and plasma endothelin-1 in healthy adults by Ballard, Kevin D, Timsina, Roshan, Timmerman, Kyle L

“…Reduced flow-mediated dilation (FMD) and elevated plasma endothelin-1 (ET-1) levels may contribute to the higher incidence of adverse cardiovascular events…”
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Exercise training-induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise? by Timmerman, Kyle L., Flynn, Michael G., Coen, Paul M., Markofski, Melissa M., Pence, Brandt D.

“…Exercise training or higher levels of physical activity are known to exert anti‐inflammatory effects. CD14+CD16+ monocytes are potent producers of inflammatory…”
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A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults by L TIMMERMAN, Kyle, DHANANI, Shaheen, L GLYNN, Erin, S FRY, Christopher, J DRUMMOND, Micah, JENNINGS, Kristofer, RASMUSSEN, Blake B, VOLPI, Elena

“…Nutrient stimulation of muscle protein anabolism is blunted with aging and may contribute to the development and progression of sarcopenia in older adults…”
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Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women by Markofski, Melissa M., Dickinson, Jared M., Drummond, Micah J., Fry, Christopher S., Fujita, Satoshi, Gundermann, David M., Glynn, Erin L., Jennings, Kristofer, Paddon-Jones, Douglas, Reidy, Paul T., Sheffield-Moore, Melinda, Timmerman, Kyle L., Rasmussen, Blake B., Volpi, Elena

“…The rate of muscle loss with aging is higher in men than women. However, women have smaller muscles throughout the adult life. Protein content is a major…”
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Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults by Drummond, Micah J, Dickinson, Jared M, Fry, Christopher S, Walker, Dillon K, Gundermann, David M, Reidy, Paul T, Timmerman, Kyle L, Markofski, Melissa M, Paddon-Jones, Douglas, Rasmussen, Blake B, Volpi, Elena

“…Skeletal muscle atrophy during bed rest is attributed, at least in part, to slower basal muscle protein synthesis (MPS). Essential amino acids (EAA) stimulate…”
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An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle by Drummond, Micah J, Glynn, Erin L, Fry, Christopher S, Timmerman, Kyle L, Volpi, Elena, Rasmussen, Blake B

“…Essential amino acids (EAA) stimulate skeletal muscle mammalian target of rapamycin complex 1 (mTORC1) signaling and protein synthesis. It has recently been…”
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Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial by Markofski, Melissa M, Jennings, Kristofer, Timmerman, Kyle L, Dickinson, Jared M, Fry, Christopher S, Borack, Michael S, Reidy, Paul T, Deer, Rachel R, Randolph, Amanda, Rasmussen, Blake B, Volpi, Elena

“…Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. In this Phase 1,…”
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Perceptions of Weight Loss in Older Adults Following a 6-Month Weight Loss Program: A Qualitative Research Study by Miller, M. Elizabeth, Newton, Kelsie, Bailey, Audrey, Monnier, Chantal, Hoersten, Isabella, Puthoff, Iris, Klinker, Abigail, Timmerman, Kyle L.

“…Obesity in older adults contributes to increasing comorbidities and decreased quality of life. There is limited research that includes older adults’…”
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Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids by Dickinson, Jared M, Fry, Christopher S, Drummond, Micah J, Gundermann, David M, Walker, Dillon K, Glynn, Erin L, Timmerman, Kyle L, Dhanani, Shaheen, Volpi, Elena, Rasmussen, Blake B

“…The relationship between mammalian target of rapamycin complex 1 (mTORC1) signaling and muscle protein synthesis during instances of amino acid surplus in…”
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Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women by Glynn, Erin L, Fry, Christopher S, Drummond, Micah J, Timmerman, Kyle L, Dhanani, Shaheen, Volpi, Elena, Rasmussen, Blake B

“…Essential amino acids (EAA) stimulate skeletal muscle protein synthesis (MPS) in humans. Leucine may have a greater stimulatory effect on MPS than other EAA…”
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Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling by Timmerman, Kyle L., Lee, Jessica L., Dreyer, Hans C., Dhanani, Shaheen, Glynn, Erin L., Fry, Christopher S., Drummond, Micah J., Sheffield-Moore, Melinda, Rasmussen, Blake B., Volpi, Elena

“…Objective: Our objective was to determine whether endothelial-dependent vasodilation is an essential mechanism by which insulin stimulates human skeletal…”
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Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults by Drummond, Micah J, Timmerman, Kyle L, Markofski, Melissa M, Walker, Dillon K, Dickinson, Jared M, Jamaluddin, Mohammad, Brasier, Allan R, Rasmussen, Blake B, Volpi, Elena

“…Bed rest induces significant loss of leg lean mass in older adults. Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown…”
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Exercise, Amino Acids, and Aging in the Control of Human Muscle Protein Synthesis by WALKER, Dillon K, DICKINSON, Jared M, TIMMERMAN, Kyle L, DRUMMOND, Micah J, REIDY, Paul T, FRY, Christopher S, GUNDERMANN, David M, RASMUSSEN, Blake B

“…In this review, we discuss recent research in the field of human skeletal muscle protein metabolism characterizing the acute regulation of mammalian target of…”
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Effects of prior aerobic exercise on sitting-induced vascular dysfunction in healthy men by Ballard, Kevin D., Duguid, Robert M., Berry, Craig W., Dey, Priyankar, Bruno, Richard S., Ward, Rose Marie, Timmerman, Kyle L.

“…Introduction Acute aerobic exercise prevents sitting-induced impairment of flow-mediated dilation (FMD). Further, evidence suggests that sitting-induced…”
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Amino acid metabolism and regulatory effects in aging by Timmerman, Kyle L, Volpi, Elena

“…PURPOSE OF REVIEWTo examine recent discoveries related to the amino acid metabolism and regulatory effects in aging, focusing on the development and treatment…”
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Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise by DRUMMOND, Micah J, FRY, Christopher S, GLYNN, Erin L, TIMMERMAN, Kyle L, DICKINSON, Jared M, WALKER, Dillon K, GUNDERMANN, David M, VOLPI, Elena, RASMUSSEN, Blake B

“…Amino acid transporters and mammalian target of rapamycin complex 1 (mTORC1) signaling are important contributors to muscle protein anabolism. Aging is…”
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Short term e-bicycle riding results in favorable cardiometabolic shifts in moderately active adults by Alessio, Helaine M., Ballard, Kevin D., Reidy, Paul T., Hayward, Katie M., Bagg, Alexandra M., Cooley, Rachel A., O’Connell, Michael J., Montoye, Alexander H. K., Timmerman, Kyle L.

“…Purpose Electric bikes (EB) are a form of active transportation with demonstrated health benefits. The purpose of this study was to determine the influence of…”
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