Search Results - "Timmerman, Arie J"
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Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease
Published in Acta neuropathologica communications (29-06-2014)“…Alzheimer's disease is caused by increased production or reduced clearance of amyloid-β, which results in the formation amyloid-β plaques and triggers a…”
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(Pheo)Melanin Photosensitizes UVA-Induced DNA Damage in Cultured Human Melanocytes
Published in Journal of investigative dermatology (01-10-1998)“…The question of whether melanins are photoprotecting and/or photosensitizing in human skin cells continues to be debated. To evaluate the role of melanin upon…”
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Detection of single-strand breaks and base damage in DNA of human white blood cells as a tool for biological dosimetry of exposure to ionizing radiation
Published in Military medicine (01-02-2002)“…An immunochemical assay has been adapted to detect DNA damage in whole blood at biologically relevant doses of ionizing radiation. Upon alkaline treatment of…”
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Physiological Doses of Ultraviolet Irradiation Induce DNA Strand Breaks in Cultured Human Melanocytes, as Detected by Means of an Immunochemical Assay
Published in Photochemistry and photobiology (01-12-1997)“…— An immunochemical assay, i.e. sandwich enzyme‐linked immunosorbent assay, has been modified to detect UV‐induced damage in cellular DNA of monolayer‐grown…”
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A modified immunochemical assay for the fast detection of DNA damage in human white blood cells
Published in Mutation Research (01-06-1995)“…An immunochemical assay to detect damage in DNA has been modified to a so-called sandwich ELISA. With this assay DNA damages can be detected that give rise to…”
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(Pheo)Melanin Photosensitizes UVA-Induced DNA Damage in Cultured Human Melanocytes11This work was presented in part at the Annual Meeting of the European Society for Photobiology, Stresa, September 8–13 1997 and entirely at the Annual Meeting of the European Society for Dermatological Research, Rome, October 4–8 1997
Published in Journal of investigative dermatology (01-10-1998)“…The question of whether melanins are photoprotecting and/or photosensitizing in human skin cells continues to be debated. To evaluate the role of melanin upon…”
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DNA‐damage processing in blood lymphocytes of head‐and‐neck‐squamous‐cell‐carcinoma patients is dependent on tumor site
Published in International journal of cancer (27-09-1996)“…It has been reported that an intrinsic susceptibility to cancer is related to the way an individual responds to DNA‐damaging agents. The aim of this study was…”
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