Search Results - "Timmer, C J"

Caspase substrates by Timmer, J C, Salvesen, G S

“…The relatively common occurrence of sequences within proteins that match the consensus substrate specificity of caspases in intracellular proteins suggests a…”
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Clinical pharmacokinetics of mirtazapine by TIMMER, C. J, SITSEN, J. M. A, DELBRESSINE, L. P

“…Mirtazapine is the first noradrenergic and specific serotonergic antidepressant ('NaSSA'). It is rapidly and well absorbed from the gastrointestinal tract…”
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Pharmacokinetic Parameters of Tibolone and Metabolites in Plasma, Urine, Feces, and Bile from Ovariectomized Cynomolgus Monkeys after a Single Dose or Multiple Doses of Tibolone by VERHEUL, H. A. M, TIMMER, C. J, VAN LERSEL, M. L. P. S, DELBRESSINE, L. P. C, KLOOSTERBOER, H. J

“…Levels of nonsulfated and sulfated tibolone metabolites were determined in plasma, urine, and feces from six ovariectomized, mature female cynomolgus monkeys…”
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Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring by TIMMER, Cees J, MULDERS, Titia M. T

“…To assess the pharmacokinetics of etonogestrel and ethinylestradiol released from a novel combined contraceptive vaginal ring (NuvaRing) releasing etonogestrel…”
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Pharmacokinetic Parameters of Sulfated Tibolone Metabolites in Postmenopausal Women after Single and Multiple Doses of Tibolone by Verheul, H A M, Timmer, C J, Kloosterboer, H J

“…The objective of this study was to determine pharmacokinetic parameters of sulfated tibolone metabolites after single dose and their accumulation after…”
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Pharmacokinetics of tibolone in early and late postmenopausal women by Timmer, C. J., Verheul, H. A. M., Doorstam, D. P.

“…Aims  Tibolone is a tissue‐specific compound with favourable effects on bone, vagina, climacteric symptoms, mood and sexual well being in postmenopausal women,…”
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Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part II. Dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers by Oberyé, J J, Mannaerts, B M, Huisman, J A, Timmer, C J

“…To assess the dose-proportionality and pharmacodynamic properties of multiple doses of ganirelix (Antagon/Orgalutran; NV Organon, Oss, the Netherlands)…”
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Pharmacokinetic evaluation of gepirone immediate-release capsules and gepirone extended-release tablets in healthy volunteers by Timmer, C J, Sitsen, J M A

“…In an open-label, randomized, crossover study, the pharmacokinetics of gepirone immediate-release (gepirone-IR) and different gepirone extended-release…”
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The effectiveness of dentifrices without and with sodium lauryl sulfate on plaque, gingivitis and gingival abrasion—a randomized clinical trial by Sälzer, S., Rosema, N.A.M., Martin, E.C.J., Slot, D.E., Timmer, C. J., Dörfer, C. E., van der Weijden, G.A.

“…Objectives The aim of this study was to compare the efficacy of a dentifrice without sodium lauryl sulfate (SLS) to a dentifrice with SLS in young adults aged…”
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Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part I. Absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers by Oberyé, J J, Mannaerts, B M, Kleijn, H J, Timmer, C J

“…To assess the absolute bioavailability of ganirelix (Antagon/Orgalutran; NV Organon, Oss, the Netherlands) after a single SC injection. Randomized, crossover,…”
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Dose Proportionality of Three Different Doses of Tibolone by Timmer, Cees J., Houwing, Natalie S.

“…Study Objective. To assess dose proportionality of tibolone tablets after multiple oral administration. Design. Open‐label, randomized, three‐period crossover…”
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Pharmacokinetics and biotransformation of mirtazapine in human volunteers by Delbressine, L P, Moonen, M E, Kaspersen, F M, Wagenaars, G N, Jacobs, P L, Timmer, C J, Paanakker, J E, van Hal, H J, Voortman, G

“…This paper investigated the pharmacokinetics and biotransformation of mirtazapine in healthy human volunteers. The results showed that the area under the…”
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Concomitant use of mirtazapine and cimetidine : A drug-drug interaction study in healthy male subjects by SITSEN, J. M. A, MARIS, F. A, TIMMER, C. J

“…The objective of this study was to examine the pharmacokinetics and the tolerability/safety of mirtazapine and cimetidine separately and in combination…”
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Pharmacokinetics of mirtazapine and lithium in healthy male subjects by Sitsen, J. M. A., Voortman, G., Timmer, C. J.

“…A substantial proportion of patients diagnosed with depression and treated with antidepressants show no or insufficient response. In such patients, lithium is…”
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Mirtazapine in combination with amitriptyline: a drug-drug interaction study in healthy subjects by Sennef, C., Timmer, C. J., Sitsen, J. M. A.

“…Objective To assess the steady‐state pharmacokinetics of mirtazapine (30 mg/day orally) and amitriptyline (75 mg/day orally) during combined administration…”
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Reduction of erosion by protein-containing toothpastes by Jager, D H J, Vissink, A, Timmer, C J, Bronkhorst, E, Vieira, A M, Huysmans, M C D N J M

“…To assess the effect of protein-containing toothpastes on the progression of dental erosion in situ (with pellicle) and in vitro (without pellicle). A combined…”
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Drug-drug interaction studies with mirtazapine and carbamazepine in healthy male subjects by SITSEN, J. M. A, MARIS, F. A, TIMMER, C. J

“…In two studies, the effects of the potentially interacting drugs mirtazapine and carbamazepine on their pharmacokinetics have been investigated. Subjects were…”
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The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis by Van der Weijden, G. A., Timmer, C. J., Timmerman, M. F., Reijerse, E., Mantel, M. S., van der Velden, U.

“… The purpose of the present study was to establish in vitro the inhibiting effect of a herbal extract mixture on a selected number of micro‐organisms and to…”
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Making a Lecture Stick: the Effect of Spaced Instruction on Knowledge Retention in Medical Education by Timmer, Marnix C. J., Steendijk, Paul, Arend, Sandra M., Versteeg, Marjolein

“…Introduction Poor knowledge retention is a persistent problem among medical students. This challenging issue may be addressed by optimizing frequently used…”
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Bioavailability and bioequivalence of etonogestrel from two oral formulations of desogestrel : Cerazette® and Liseta by TIMMER, C. J, SRIVASTAVA, N, DIEBEN, T. O. M, COHEN, A. F

“…In a three-period cross-over study with 24 healthy young females (study part 1), the bioavailability of etonogestrel (3-ketodesogestrel) was determined after a…”
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