Search Results - "Timmann, C."

Incidence and clinical features of hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) and spectrum of mevalonate kinase (MVK) mutations in German children by Lainka, E., Neudorf, U., Lohse, P., Timmann, C., Bielak, M., Stojanov, S., Huss, K., von Kries, R., Niehues, T.

“…Autoinflammatory diseases (AIDs) are characterized by recurrent, self-limiting systemic inflammation. Disorders include hereditary recurrent fever (HRF)…”
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Incidence of TNFRSF1A mutations in German children: epidemiological, clinical and genetic characteristics by Lainka, Elke, Neudorf, Ulrich, Lohse, Peter, Timmann, Christian, Stojanov, Silvia, Huss, Kristina, von Kries, Rudiger, Niehues, Tim

“…Objective. TNF receptor 1-associated periodic syndrome (TRAPS) is a rare disease belonging to the heterogeneous group of hereditary periodic fever (HPF)…”
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Familial Mediterranean fever in Germany: epidemiological, clinical, and genetic characteristics of a pediatric population by Lainka, E., Bielak, M., Lohse, P., Timmann, C., Stojanov, S., von Kries, R., Niehues, T., Neudorf, U.

“…Familial Mediterranean fever (FMF) is an autoinflammatory disease and belongs to the heterogeneous group of hereditary recurrent fever syndromes (HRFs). Aims :…”
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Analysis of cryopyrin-associated periodic syndromes (CAPS) in German children: epidemiological, clinical and genetic characteristics by Lainka, E, Neudorf, U, Lohse, P, Timmann, C, Bielak, M, Stojanov, S, Huss, K, von Kries, R, Niehues, T

“…Cryopyrin-associated periodic syndromes (CAPS) are rare disorders belonging to the group of hereditary periodic fever (HPF)syndromes. These auto-inflammatory…”
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High mortality of infant bacteraemia clinically indistinguishable from severe malaria by Evans, J.A., Adusei, A., Timmann, C., May, J., Mack, D., Agbenyega, T., Horstmann, R.D., Frimpong, E.

“…Background: Early recognition of children at highest risk of dying and the targeting of appropriate drug therapy are vital to the improvement of paediatric…”
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Cutaneous pathology in onchocerciasis associated with pronounced systemic T-helper 2-type responses to Onchocerca volvulus by Timmann, C., Abraha, R.S., Hamelmann, C., Buttner, D.W., Lepping, B., Marfo, Y., Brattig, N., Horstmann, R.D.

“…Summary Background  Of 18 million people world‐wide who are infested with the tissue nematode Onchocerca volvulus, more than 30% are considered to have skin…”
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Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen by Timmann, C, Fuchs, S, Thoma, C, Lepping, B, Brattig, N W, Sievertsen, J, Thye, T, Müller-Myhsok, B, Horstmann, R D

“…Since interleukin (IL)-10 is a key mediator of immunosuppression, and immunosuppression is considered an important element of helminth infection, we studied…”
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Pre-treatment with chloroquine and parasite chloroquine resistance in Ghanaian children with severe malaria by Evans, J.A., May, J., Tominski, D., Eggelte, T., Marks, F., Abruquah, H.H., Meyer, C.G., Timmann, C., Agbenyega, T., Horstmann, R.D.

“…Background: Self-medication with anti-malarial drugs is widespread, and chloroquine (CQ) resistance is increasing. The effect of these factors on the incidence…”
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Relevance of ex vivo blood lymphocyte assay for in vivo lymphocyte function by Brattig, N. W., Timmann, C., Abraha, R. S., Lepping, B., Müller‐Myhsok, B., Horstmann, R. D.

“…Summary Determinations of in vitro proliferative and secretory activities of peripheral blood cells are used widely for research in clinical immunology but, to…”
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Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes by Skerka, C, Timmann, C, Horstmann, RD, Zipfel, PF

“…We identify and characterize two human serum proteins with an apparent molecular mass of 24 and 29 kDa, which are antigenically related to complement factor H…”
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Molecular diagnostics of hereditary fever syndromes. Familial Mediterranean fever (FMF), hyperimmunoglobulin D syndrome (HIDS), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), cryopyrin-associated periodic syndrome (CAPS: FCAS, MWS, NOMID/CINCA) by Timmann, C, Horstmann, R

“…Periodic episodes of fever and inflammation can have a genetic origin. Nowadays, the identification of the causative genetic variants in the majority of cases…”
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Hereditäre Fiebersyndrome by Schumacher, J., Timmann, C.

“…Zusammenfassung Das familiäre Mittelmeerfieber (FMF), Hyper-IgD-Syndrom (HIDS) und das Tumornekrosefaktor(TNF)-Rezeptor-1-assoziierte periodische Syndrom…”
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FCGR2A functional genetic variant associated with susceptibility to severe malarial anaemia in Ghanaian children by Schuldt, Kathrin, Esser, Claudia, Evans, Jennifer, May, Jürgen, Timmann, Christian, Ehmen, Christa, Loag, Wibke, Ansong, Daniel, Ziegler, Andreas, Agbenyega, Tsiri, Meyer, Christian G, Horstmann, Rolf D

“…Severe malarial anaemia is a major cause of mortality from malaria. Although of enormous relevance, its pathogenesis is largely unknown. Interestingly, the…”
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Molekulargenetische Diagnostik erblicher Fiebersyndrome: Familiäres Mittelmeerfieber (FMF), Hyperimmunglobulin-D-Syndrom (HIDS), TNF-rezeptorassoziiertes periodisches Syndrom (TRAPS), Cryopyrin-assoziiertes periodisches Syndrom (CAPS: FCAS, MWS, NOMID/CINCA) by Timmann, C., Horstmann, R.

“…Zusammenfassung Chronisch rezidivierende Episoden mit Fieber und Entzündungszeichen können auch erblich bedingt sein. Die Entdeckung der verursachenden…”
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Human Genetic Resistance to Onchocerca volvulus: Evidence for Linkage to Chromosome 2p from an Autosome-Wide Scan by Timmann, Christian, van der Kamp, Esther, Kleensang, André, König, Inke R., Thye, Thorsten, Büttner, Dietrich W., Hamelmann, Christoph, Marfo, Yeboah, Vens, Maren, Brattig, Norbert, Ziegler, Andreas, Horstmann, Rolf D.

“…Background. Human infections with the tissue nematode Onchocerca volvulus show strong interindividual variation in intensity, which cannot be explained by…”
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Molekulargenetische Diagnostik erblicher Fiebersyndrome: Familiäres Mittelmeerfieber (FMF), Hyperimmunglobulin-D-Syndrom (HIDS), TNF-rezeptorassoziiertes periodisches Syndrom (TRAPS), Cryopyrin-assoziiertes periodisches Syndrom (CAPS: FCAS, MWS, NOMID/CINCA) : Autoinflammation by TIMMANN, C, HORSTMANN, R

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Selection for deafness? by Meyer, Christian G, Amedofu, Geoffrey K, Brandner, Johanna M, Pohland, Dieter, Timmann, Christian, Horstmann, Rolf D

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Molecular diagnostics of hereditary fever syndromes. Familial Mediterranean fever (FMF), hyperimmunoglobulin D syndrome (HIDS), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), cryopyrin-associated periodic syndrome (CAPS: FCAS, MWS, NOMID/CINCA) by Timmann, C, Horstmann, R

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Onchocerca volvulus-Exposed Persons Fail to Produce Interferon-γ in Response to O. volvulus Antigen but Mount Proliferative Responses with Interleukin-5 and IL-13 Production that Decrease with Increasing Microfilarial Density by Brattig, Norbert W., Lepping, Bianca, Timmann, Christian, Büttner, Dietrich W., Marfo, Yeboah, Hamelmann, Christoph, Horstmann, Rolf D.

“…The cellular immune response to Onchocerca volvulus antigen (OvAg) was studied in 551 persons exposed to O. volvulus transmission in a hyperendemic area of…”
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Promoter Polymorphism of the Anion-Exchange Protein 1 Associated with Severe Malarial Anemia and Fatality by Kalckreuth, Vera von, Evans, Jennifer A., Timmann, Christian, Kuhn, Daniela, Agbenyega, Tsiri, Horstmann, Rolf D., May, Jürgen

“…The anion-exchange protein 1 (AE1 or band 3) is involved in the erythrocyte invasion of the malaria parasite Plasmodium falciparum the adhesion of infected…”
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