Search Results - "Timina, E A"

Preclinical Studie of General Toxic Properties of Preparations Containing Ultralow Doses of Antibodies to Endogenous Regulators by Karpova, G. V, Fomina, T. I, Vetoshkina, T. V, Dubskaya, T. Yu, Voronova, O. L, Timina, E. A, Abramova, E. V, Ermolaeva, L. A, Perova, A. V

“…Preclinical study of the safety of 6 preparations containing ultralow doses of antibodies to endogenous regulators showed that they are relatively safe, are…”
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Stress-inducing effect of hypoxia of different origin and its correction with Inula Helenium L. tincture by Zelenskaya, K L, Povet'eva, T N, Pashinskii, V G, Fomina, T N, Timina, E A, Perova, A V

“…In order to evaluate the severity of stress, the effects of single and repeated exposure to hypoxia of different origin (hemic, tissue, and circulatory) on the…”
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Effect of vepeside on the function of reproductive system in rats by Borovskaya, T G, Gol'dberg, V E, Poluektova, M E, Timina, E A, Shchemerova, Yu A, Perova, A V

“…Experiments on adult rats showed that a single intravenous injection of antitumor drug vepeside in a MTD (maximum tolerable dose) reduced the reproductive…”
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Status of the progeny of rats treated with platinum-containing cytostatics by Borovskaya, T G, Gol'dberg, V E, Poluektova, M E, Pakhomova, A V, Timina, E A, Gol'dberg, E D

“…Wistar rat pups from rats treated with first- and second-generation platinum-containing cytostatics (platidiam, carboplatin) 1, 3, and 6 months before mating…”
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Carcinogenic effect of an antitumor drug etoposide in laboratory animals by Fomina, T I, Perelmuter, V M, Vtorushin, S V, Zavjalova, M V, Borovskaja, T G, Timina, E A

“…Intravenous injection of antitumor drug etoposide in the maximum tolerated dose was followed by the development of breast cancer in 38.1% female Wistar rats…”
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Induced cell death and its role in hemopoietic hypoplasia after cytostatic treatment by Gol'dberg, E. D., Karpova, G. V., Timina, E. A., Khlusov, I. A.

“…The morphological signs of apoptosis in the bone-marrow cells and thymocytes, indices of cellularity in these organs and in peripheral blood and the absolute…”
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Morphological and functional state of rat ovaries in the early and late periods after injection of vepesid by Borovskaya, T G, Gol'dberg, V E, Pakhomova, A V, Perova, A V, Timina, E A

“…Morphological and functional state of the ovaries in female Wistar rats was assessed in the early and late periods after administration of antitumor drug…”
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Spermatogenesis in rats after injection of the antitumor drug vepeside by Gol'dberg, E. D., Borovskaya, T. G., Timina, E. A., Fomina, T. I., Gol'dberg, V. E.

“…Stable morphological changes and disorders of spermatogenesis develop in the testicles of Wistar rats during 30 days after a single injection of vepeside in…”
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Pharmacological correction of etoposide ovariotoxicity by Borovskaya, T G, Timina, E A, Perova, A V, Pakhomova, A V, Shchemerova, Yu A, Gol'dberg, V E

“…The possibility of reducing the ovariotoxicity of antitumor drug etoposide with buserelin, a hypothalamic regulator of pituitary function, was studied in…”
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Evaluation of the progeny of rats treated with topoisomerase II inhibitor vepesid by Borovskaya, T G, Gol'dberg, V E, Shchemerova, Yu A, Perova, A V, Timina, E A, Pakhomova, A V

“…Progeny of Wistar rats treated with vepesid 1, 3, and 6 months before mating is characterized by common pathological changes. These changes were more…”
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Effect of paclitaxel on morphology and function of rat ovaries by Borovskaya, T. G., Pakhomova, A. V., Perova, A. V., Timina, E. A., Gol’dberg, V. E.

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State of progeny from rats receiving paclitaxel by Borovskaya, T. G., Perova, A. V., Timina, E. A., Pakhomova, A. V., Gol’dberg, V. E.

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Preclinical studied of general toxic properties of preparations containing ultralow doses of antibodies to endogenous regulators by Karpova, G V, Fomina, T I, Vetoshkina, T V, Dubskaya, T Yu, Voronova, O L, Timina, E A, Abramova, E V, Ermolaeva, L A, Perova, A V

“…Preclinical study of the safety of 6 preparations containing ultralow doses of antibodies to endogenous regulators showed that they are relatively safe, are…”
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Reaction of the blood system in pregnant rats at late terms after etoposide treatment by Timina, E. A., Karpova, G. V., Churin, A. A., Borovskaya, T. G., Lamzina, T. Yu, Gol’dberg, V. E.

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Myelotoxicity of paclitaxel (mitotax) by Karpov, G V, Fomina, T I, Voronova, O L, Abramova, E V, Timina, E A, Lamzina, T Iu, Ermolaeva, L A, Perova, A V

“…Paclitaxel (single intravenous injection in a maximum tolerated dose of 4.6 mg/kg) to white outbred rats causes bone marrow hypoplasia, increased granulocyte…”
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Myelotoxicity of high-molecular-weight poly(ethylene oxide) by Karpova, G V, Abramova, E V, Lamzina, T Iu, Timina, E A, Vetoshkina, T V

“…The effects of administration of the parent substance of high-molecular-weight poly(ethylene oxide) (HMWPEO) with a molecular mass of 3-6 x 10(6) D and the…”
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Delayed response of the red blood system (erythron) to carboplatin administration during pregnancy by Karpova, G V, Borovskaia, T G, Timina, E A, Pakhomova, A V

“…Pregnant rats exhibited regenerative anemia development 3 months upon a single intravenous injection of carboplatin in a maximum tolerated dose; the effect…”
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Morphological estimation of apoptosis in preclinical studies of new drugs by Karpova, G V, Timina, E A, Karpova, M R

“…A method for morphological estimation of the thymus cell loss during apoptosis proposed, which can be used as a screening test in the stage of preclinical…”
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Effect of human recombinant granulocyte colony-stimulating factor on mouse hematopoietic and lymphoid organs by Karpova, G V, Fomina, T I, Timina, E A, Abramova, E V, Masycheva, V I, Pustoshilova, N M

“…Experiments on intact CBA/CALac mice demonstrated that single (1.25 mg/kg) and repeated (0.125 and 1.25 mg/kg, 30 days) injections of recombinant human…”
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The mechanisms of the hepatotoxic action of the antitumor preparation vepesid by Vetoshkina, T V, Dubskaia, T Iu, Timina, E A, Gol'dberg, V E

“…It was shown in experiments on rats that intravenous infusion of the antitumor drug vepesid in a maximum tolerated dose causes stimulation of free-radical…”
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