Search Results - "Timbergen, M J"
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Radiomics approach to distinguish between well differentiated liposarcomas and lipomas on MRI
Published in British journal of surgery (01-12-2019)“…Background Well differentiated liposarcoma (WDLPS) can be difficult to distinguish from lipoma. Currently, this distinction is made by testing for MDM2…”
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Differential Diagnosis and Molecular Stratification of Gastrointestinal Stromal Tumors on CT Images Using a Radiomics Approach
Published in Journal of digital imaging (01-04-2022)“…Treatment planning of gastrointestinal stromal tumors (GISTs) includes distinguishing GISTs from other intra-abdominal tumors and GISTs’ molecular analysis…”
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Assessing the Desmoid-Type Fibromatosis Patients’ Voice: Comparison of Health-Related Quality of Life Experiences from Patients of Two Countries
Published in Complexity (New York, N.Y.) (2020)“…Purpose. Desmoid-type fibromatosis (DTF) is a rare, nonmetastasising soft tissue tumour. Symptoms, unpredictable growth, lack of definitive treatments, and the…”
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Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study
Published in Quality of life research (01-12-2018)“…Purpose Sporadic desmoid-type fibromatosis (DTF) is a rare, chronic, non-metastasising, disease of the soft tissues. It is characterised by local invasive and…”
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Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review
Published in Frontiers in oncology (17-05-2019)“…Desmoid-type fibromatosis (DTF) is a rare, soft tissue tumor of mesenchymal origin which is characterized by local infiltrative growth behavior. Besides "wait…”
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Active surveillance in desmoid-type fibromatosis: A systematic literature review
Published in European journal of cancer (1990) (01-09-2020)“…This study evaluates the results of the active surveillance (AS) approach in adult patients with desmoid-type fibromatosis (DTF) because AS is advocated as a…”
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Unraveling Desmoid-Type Fibromatosis-Specific Health-Related Quality of Life: Who Is at Risk for Poor Outcomes
Published in Cancers (16-06-2022)“…Desmoid-type fibromatosis (DTF) is a rare, soft-tissue tumour. These tumours do not metastasize, but their local aggressive tumour growth and unpredictable…”
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Development of a Disease-Specific Health-Related Quality of Life Questionnaire (DTF-QoL) for Patients with Desmoid-Type Fibromatosis
Published in Cancers (29-01-2022)“…Sporadic desmoid-type fibromatosis (DTF) is a rare, non-metastasising soft-tissue tumour. Patients can experience a variety of disease-specific issues related…”
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The Evaluation of Health-Related Quality of Life Issues Experienced by Patients with Desmoid-Type Fibromatosis (The QUALIFIED Study)—A Protocol for an International Cohort Study
Published in Cancers (22-06-2021)“…Sporadic desmoid-type fibromatosis (DTF) is a rare soft tissue tumour with an unpredictable clinical course. These tumours are incapable of metastasising, but…”
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Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors
Published in Frontiers in oncology (29-10-2020)“…The majority of desmoid-type fibromatosis (DTF) tumors harbor a β-catenin mutation, affecting specific codons in exon 3. S45F tumors are reported to have a…”
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Physical symptom burden in patients with desmoid‐type fibromatosis and its impact on health‐related quality of life and healthcare use
Published in Cancer medicine (Malden, MA) (01-06-2023)“…Background Desmoid‐type fibromatosis (DTF) has a highly variable clinical course with varying intensity of symptoms. The objectives of this study were to…”
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A Nationwide Prospective Clinical Trial on Active Surveillance in Patients With Non-intraabdominal Desmoid-type Fibromatosis: The GRAFITI Trial
Published in Annals of surgery (01-04-2023)“…To assess tumor behavior and the efficacy of active surveillance (AS) in patients with desmoid-type fibromatosis (DTF). AS is recommended as initial management…”
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The Prognostic Role of β-Catenin Mutations in Desmoid-type Fibromatosis Undergoing Resection Only: A Meta-analysis of Individual Patient Data
Published in Annals of surgery (01-06-2021)“…OBJECTIVE:This meta-analysis (PROSPERO CRD42018100653) uses individual patient data (IPD) to assess the association between recurrence and CTNNB1 mutation…”
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Venous In-stent Thrombosis Treated by Ultrasound Accelerated Catheter Directed Thrombolysis
Published in European journal of vascular and endovascular surgery (01-04-2015)“…Objective/Background Stent placement in the venous system is an increasingly used treatment modality in chronic venous obstruction and as additional treatment…”
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Health-related Quality of Life of Patients with Non-intra-abdominal Desmoid-type Fibromatosis during Active Surveillance: Results of a Prospective Observational Study
Published in Annals of surgery (01-06-2023)“…To examine the impact of an active surveillance (AS) approach on the health-related quality of life (HRQoL) of patients with desmoid-type fibromatosis (DTF)…”
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Differential diagnosis and mutation stratification of desmoid-type fibromatosis on MRI using radiomics
Published in European journal of radiology (01-10-2020)“…•Radiomics can distinguish between desmoid-type fibromatotis (DTF) and soft tissue sarcomas (STS).•Radiomics performs similar to radiologists in distinguishing…”
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Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations
Published in European journal of surgical oncology (01-04-2019)“…Sporadic desmoid-type fibromatosis (DTF) is a rare soft tissue tumor of mesenchymal origin. It is characterized by local invasive growth and unpredictable…”
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In desmoid-type fibromatosis cells sorafenib induces ferroptosis and apoptosis, which are enhanced by autophagy inhibition
Published in European journal of surgical oncology (01-07-2022)“…Desmoid-type fibromatosis (DTF) is a rare, soft tissue tumour. Sorafenib, a multikinase inhibitor, has demonstrated antitumour efficacy in DTF patients. Little…”
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1682PHealth-related quality of life issues of patients affected by desmoid-type fibromatosis: Experiences from two countries
Published in Annals of oncology (01-10-2019)“…Abstract Background Desmoid-type fibromatosis (DTF) is a rare, non-metastasising soft tissue tumour, which by local growth can significantly impact health…”
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1708PDifferentiating well-differentiated liposarcomas from lipomas using a radiomics approach
Published in Annals of oncology (01-10-2019)“…Abstract Background Well-differentiated liposarcomas (WDLPS) can be difficult to distinguish from lipomas. Currently, this distinction is made by testing for…”
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