Search Results - "Timans, J"

Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2 by Debets, R, Timans, J C, Homey, B, Zurawski, S, Sana, T R, Lo, S, Wagner, J, Edwards, G, Clifford, T, Menon, S, Bazan, J F, Kastelein, R A

“…IL-1 is of utmost importance in the host response to immunological challenges. We identified and functionally characterized two novel IL-1 ligands termed…”
Get full text

A newly defined interleukin-1? by Bazan, J. Fernando, Timans, Jackie C, Kastelein, Robert A

“…Okamura et al. report the cloning of a novel, stress-induced cytokine from mouse liver which has biological actions in T cells that are strikingly reminiscent…”
Get full text

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12 by Oppmann, Birgit, Lesley, Robin, Blom, Bianca, Timans, Jackie C, Xu, Yuming, Hunte, Brisdell, Vega, Felix, Yu, Nancy, Wang, Jing, Singh, Komal, Zonin, Francesca, Vaisberg, Elena, Churakova, Tatyana, Liu, Man-ru, Gorman, Daniel, Wagner, Janet, Zurawski, Sandra, Liu, Yong-Jun, Abrams, John S, Moore, Kevin W, Rennick, Donna, de Waal-Malefyt, Rene, Hannum, Charles, Bazan, J.Fernando, Kastelein, Robert A

“…A novel sequence discovered in a computational screen appears distantly related to the p35 subunit of IL-12. This factor, which we term p19, shows no…”
Get full text

A Family of Human Receptors Structurally Related to Drosophila Toll by Rock, Fernando L., Hardiman, Gary, Timans, Jackie C., Kastelein, Robert A., Bazan, J. Fernando

“…The discovery of sequence homology between the cytoplasmic domains of Drosophila Toll and human interleukin 1 receptors has sown the conviction that both…”
Get full text

IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-18 by Debets, Reno, Timans, Jackie C, Churakowa, Tatyana, Zurawski, Sandra, de Waal Malefyt, Rene, Moore, Kevin W, Abrams, John S, O'Garra, Anne, Bazan, J. Fernando, Kastelein, Robert A

“…IL-18 is critical in eliciting IFN-gamma production from Th1 cells both in vitro and in vivo. Th1 cells have been implicated in the pathogenesis of autoimmune…”
Get full text

Proteoglycan Forms of the Lymphocyte Homing Receptor CD44 Are Alternatively Spliced Variants Containing The v3 Exon by Jackson, David G., Bell, John I., Dickinson, Richard, Timans, Jackie, Shields, John, Whittle, Nigel

“…The CD44 cell surface glycoprotein is expressed on a broad range of different tissues as multiple isoforms containing from one to ten alternatively spliced…”
Get full text

Expression of snowdrop lectin in transgenic tobacco plants results in added protection against aphids by HILDER, V. A, POWELL, K. S, PEUMANS, W. J, VAN DAMME, E, BOULTER, D, GATEHOUSE, A. M. R, GATEHOUSE, J. A, GATEHOUSE, L. N, SHI, Y, HAMILTON, W. D. O, MERRYWEATHER, A, NEWELL, C. A, TIMANS, J. C

“…The range of sap-sucking insect pests to which GNA, (the mannose specific lectin from snowdrops (Galanthus nivalis)) has been shown to be insecticidal in…”
Get full text

OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily by Patel, N, Brinkman-Van der Linden, E C, Altmann, S W, Gish, K, Balasubramanian, S, Timans, J C, Peterson, D, Bell, M P, Bazan, J F, Varki, A, Kastelein, R A

“…We report the expression cloning of a novel leptin-binding protein of the immunoglobulin superfamily (OB-BP1) and a cross-hybridizing clone (OB-BP2) that is…”
Get full text

Infrared absorption in silicon at elevated temperatures by Rogne, H., Timans, P. J., Ahmed, H.

“…Isothermal electron beam heating combined with in situ optical measurements has been used to measure the temperature dependence of the spectral emissivity of…”
Get full text

A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12R beta 1 and a Novel Cytokine Receptor Subunit, IL-23R by Parham, C, Chirica, M, Timans, J, Vaisberg, E, Travis, M, Cheung, J, Pflanz, S, Zhang, R, Singh, K P, Vega, F, To, W, Wagner, J, O'Farrell, A, McClanahan, T, Zurawski, S, Hannum, C, Gorman, D, Rennick, D M, Kastelein, R A, de Waal Malefyt, R, Moore, K W

“…IL-23 is a heterodimeric cytokine composed of the IL-12p40 "soluble receptor" subunit and a novel cytokine-like subunit related to IL-12p35, termed p19. Human…”
Get full text

Device scaling effect on the spectral-directional absorptance of wafer’s front side by Fu, Kang, Chen, Yu-Bin, Hsu, Pei-feng, Zhang, Zhuomin M., Timans, Paul J.

“…Nonuniform absorption of thermal radiation in the rapid thermal processing of wafers is a critical problem facing the semiconductor industry. This paper…”
Get full text

Uniformity optimization techniques for rapid thermal processing systems by Acharya, N., Kirtikar, V., Shooshtarian, S., Hong Doan, Timans, P.J., Balakrishnan, K.S., Knutson, K.L.

“…This paper presents two efficient robust methods for uniformity optimization of rapid thermal processes. Both of these methods involve the reuse of empirical…”
Get full text

Computational Identification, Cloning, and Characterization of IL-1R9, a Novel Interleukin-1 Receptor-like Gene Encoded over an Unusually Large Interval of Human Chromosome Xq22.2–q22.3 by Sana, Theodore R., Debets, Reno, Timans, Jackie C., Bazan, J.Fernando, Kastelein, Robert A.

“…The Interleukin-1 receptor (IL-1R) and Toll signaling pathways share the evolutionarily conserved Toll homology domain (THD), which is a critical component in…”
Get full text

Dental services for children with mental handicaps: policy changes and parental choices by Timans, J K

Get full text

Room-temperature CO2 laser radiation detector by SRINIVAS, T. A. S, TIMANS, P. J, BUTCHER, R. J, AHMED, H

“…A novel microthermopile for CO2 laser radiation detection with a fast response time has been fabricated for the first time. The microthermopile is fabricated…”
Get full text

Functional Replacement of Cytokine Receptor Extracellular Domains by Leucine Zippers by Patel, Neela, Herrman, Jean M., Timans, Jackie C., Kastelein, Robert A.

“…Granulocyte-macrophage colony-stimulating factor receptor signals by a complex which includes the ligand and two different receptor subunits: a low affinity α…”
Get full text

Expression and Purification of a Synthetic Human Obese Gene Product by Altmann, Scott W., Timans, Jackie C., Rock, Fernando L., Bazan, J.Fernando, Kastelein, Robert A.

“…Human obese (hOB) protein was recently identified as a secreted hormone-like factor that is exclusively produced by adipose tissue and appears to regulate the…”
Get full text

Time-resolved reflectivity techniques for dynamic studies of electron beam recrystallization of silicon-on-insulator films by TIMANS, P. J, MCMAHON, R. A, AHMED, H

“…A time-resolved reflectivity (TRR) technique has been developed for dynamic studies of swept beam heating of silicon-on-insulator (SOI) materials. The method…”
Get full text

Rapid thermal process driven intra-die device variations by Tsai, C.H., Aboy, M., Pelaz, L., Hsu, Y.H., Woon, W.Y., Timans, P.J., Lee, C.K.

“…Intra-die device variation due to pattern layout effects associated with the development of ultra-fast annealing processes is one of the major scaling…”
Get full text

Comparison of the effects of interleukin-1 alpha, interleukin-1 beta and interferon-gamma-inducing factor on the production of interferon-gamma by natural killer by Hunter, C A, Timans, J, Pisacane, P, Menon, S, Cai, G, Walker, W, Aste-Amezaga, M, Chizzonite, R, Bazan, J F, Kastelein, R A

“…Interferon-gamma inducing factor (IGIF) is a recently identified cytokine which stimulates the production of interferon-gamma (IFN-gamma) by T cells and…”
Get more information