Search Results - "Tim O’Brien"

Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines by Swaminathan, Vinay, Mythreye, Karthikeyan, O'Brien, E Tim, Berchuck, Andrew, Blobe, Gerard C, Superfine, Richard

“…Cancer cells are defined by their ability to invade through the basement membrane, a critical step during metastasis. While increased secretion of proteases,…”
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Physical determinants of fibrinolysis in single fibrin fibers by Bucay, Igal, O'Brien, 3rd, E Tim, Wulfe, Steven D, Superfine, Richard, Wolberg, Alisa S, Falvo, Michael R, Hudson, Nathan E

“…Fibrin fibers form the structural backbone of blood clots; fibrinolysis is the process in which plasmin digests fibrin fibers, effectively regulating the size…”
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HIF1α and HIF2α independently activate SRC to promote melanoma metastases by Hanna, Sara C, Krishnan, Bhavani, Bailey, Sean T, Moschos, Stergios J, Kuan, Pei-Fen, Shimamura, Takeshi, Osborne, Lukas D, Siegel, Marni B, Duncan, Lyn M, O'Brien, 3rd, E Tim, Superfine, Richard, Miller, C Ryan, Simon, M Celeste, Wong, Kwok-Kin, Kim, William Y

“…Malignant melanoma is characterized by a propensity for early lymphatic and hematogenous spread. The hypoxia-inducible factor (HIF) family of transcription…”
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Time-lapse imaging and cell-specific expression profiling reveal dynamic branching and molecular determinants of a multi-dendritic nociceptor in C. elegans by Smith, Cody J., Watson, Joseph D., Spencer, W. Clay, O'Brien, Tim, Cha, Byeong, Albeg, Adi, Treinin, Millet, Miller, David M.

“…Nociceptive neurons innervate the skin with complex dendritic arbors that respond to pain-evoking stimuli such as harsh mechanical force or extreme…”
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Robotic-assisted Laparoscopic Radical Cystectomy with Extracorporeal Urinary Diversion: Initial Experience by Murphy, Declan G, Challacombe, Ben J, Elhage, Oussama, O’Brien, Tim S, Rimington, Peter, Khan, Mohammad Shamim, Dasgupta, Prokar

“…Abstract Background The use of robotic technology for laparoscopic prostatectomy is now well established. The same cannot yet be said of robotic-assisted…”
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Community structure and diversity of tropical forest mammals: data from a global camera trap network by Ahumada, Jorge A., Silva, Carlos E. F., Gajapersad, Krisna, Hallam, Chris, Hurtado, Johanna, Martin, Emanuel, McWilliam, Alex, Mugerwa, Badru, O'Brien, Tim, Rovero, Francesco, Sheil, Douglas, Spironello, Wilson R., Winarni, Nurul, Andelman, Sandy J.

“…Terrestrial mammals are a key component of tropical forest communities as indicators of ecosystem health and providers of important ecosystem services…”
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Characterization of Small Renal Tumors With Magnetic Resonance Elastography: A Feasibility Study by Prezzi, Davide, Neji, Radhouene, Kelly-Morland, Christian, Verma, Hema, OʼBrien, Tim, Challacombe, Ben, Fernando, Archana, Chandra, Ashish, Sinkus, Ralph, Goh, Vicky

“…OBJECTIVESThe aim of this study was to explore the feasibility of magnetic resonance elastography (MRE) for characterizing indeterminate small renal tumors…”
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Regulation of E-cadherin expression by VHL and hypoxia-inducible factor by Esteban, Miguel A, Tran, Maxine G B, Harten, Sarah K, Hill, Peter, Castellanos, Maria C, Chandra, Ashish, Raval, Raju, O'brien, Tim S, Maxwell, Patrick H

“…Mutations in von Hippel-Lindau tumor suppressor gene (VHL) underlie the VHL hereditary cancer syndrome and also occur in most sporadic clear cell renal cell…”
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Protocol for a MULTI-centre feasibility study to assess the use of 99mTc-sestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study) by Warren, Hannah, Wagner, Thomas, Gorin, Michael A, Rowe, Steven, Holman, Beverley Fiona, Pencharz, Deborah, El-Sheikh, Soha, Barod, Ravi, Patki, Prasad, Mumtaz, Faiz, Bex, Axel, Kasivisvanathan, Veeru, Moore, Caroline M, Campain, Nicholas, Cartledge, Jon, Scarsbrook, Andrew, Hassan, Fahim, O'Brien, Tim S, Stewart, Grant D, Mendichovszky, Iosif, Dizdarevic, Sabina, Alanbuki, Ammar, Wildgoose, William H, Wah, Tze, Vindrola-Padros, Cecilia, Pizzo, Elena, Dehbi, Hakim-Moulay, Lorgelly, Paula, Gurusamy, Kurinchi, Emberton, Mark, Tran, Maxine G B

“…IntroductionThe incidence of renal tumours is increasing and anatomic imaging cannot reliably distinguish benign tumours from renal cell carcinoma. Up to 30%…”
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A high throughput array microscope for the mechanical characterization of biomaterials by Cribb, Jeremy, Osborne, Lukas D, Hsiao, Joe Ping-Lin, Vicci, Leandra, Meshram, Alok, O'Brien, 3rd, E Tim, Spero, Richard Chasen, Taylor, 2nd, Russell, Superfine, Richard

“…In the last decade, the emergence of high throughput screening has enabled the development of novel drug therapies and elucidated many complex cellular…”
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Weight loss is proportional to increases in fasting serum beta-hydroxybutyrate concentrations in adults with severe obesity undergoing a meal replacement programme by Finucane, Francis Martin, Rafey, Mohammed Faraz, Leahy, Martin, O'Shea, Paula, O'Brien, Tim, O'Donnell, Martin

“…A better understanding of the influence of restricted dietary intake on circulating ketone concentrations might help to explain heterogeneity in the amount of…”
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THE RADIO LIGHT CURVE OF THE GAMMA-RAY NOVA IN V407 CYG: THERMAL EMISSION FROM THE IONIZED SYMBIOTIC ENVELOPE, DEVOURED FROM WITHIN BY THE NOVA BLAST by CHOMIUK, LAURA, Krauss, Miriam I, RUPEN, MICHAEL P, Nelson, Thomas, Roy, Nirupam, Sokoloski, Jennifer L, Mukai, Koji, Munari, Ulisse, Mioduszewski, Amy, Weston, Jennifer, O'Brien, Tim J, Eyres, Stewart P S, Bode, Michael F

“…We present multi-frequency radio observations of the 2010 nova event in the symbiotic binary V407 Cygni, obtained with the Karl G. Jansky Very Large Array…”
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Hexylaminolaevulinate fluorescence cystoscopy in patients previously treated with intravesical bacille Calmette‐Guérin by Ray, Eleanor R., Chatterton, Kathryn, Khan, M. Shamim, Chandra, Ashish, Thomas, Kay, Dasgupta, Prokar, O’Brien, Tim S.

“…Study Type – Diagnosis (case series) Level of Evidence 4 OBJECTIVE To determine if hexylaminolaevulinate fluorescence cystoscopy (HAL‐FC) has the potential to…”
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Perioperative management including dual cell salvage in a Jehovah's Witness patient undergoing major urological surgery by Smith, Thomas G., Anastasescu, Irina, Wight, James M., Danaee, Anicee, Nair, Rajesh, O'Brien, Tim S.

“…Complex surgery associated with major hemorrhage presents particular risks for Jehovah's Witnesses who do not accept transfusion of blood products…”
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Protocol for a MULTI-centre feasibility study to assess the use of 99m Tc-sestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study) by Warren, Hannah, Wagner, Thomas, Gorin, Michael A, Rowe, Steven, Holman, Beverley Fiona, Pencharz, Deborah, El-Sheikh, Soha, Barod, Ravi, Patki, Prasad, Mumtaz, Faiz, Bex, Axel, Kasivisvanathan, Veeru, Moore, Caroline M, Campain, Nicholas, Cartledge, Jon, Scarsbrook, Andrew, Hassan, Fahim, O'Brien, Tim S, Stewart, Grant D, Mendichovszky, Iosif, Dizdarevic, Sabina, Alanbuki, Ammar, Wildgoose, William H, Wah, Tze, Vindrola-Padros, Cecilia, Pizzo, Elena, Dehbi, Hakim-Moulay, Lorgelly, Paula, Gurusamy, Kurinchi, Emberton, Mark, Tran, Maxine G B

“…The incidence of renal tumours is increasing and anatomic imaging cannot reliably distinguish benign tumours from renal cell carcinoma. Up to 30% of renal…”
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Assessing the prevalence of protected species consumption by rural communities in Makira Natural Park, Madagascar, through the unmatched count technique by Spira, Charlotte, Raveloarison, Rivo, Cournarie, Morgane, Strindberg, Samantha, O'Brien, Tim, Wieland, Michelle

“…In tropical Africa, wild meat consumption by rural communities who live in or near protected areas can be a major challenge in the conservation of threatened…”
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Hexylaminolaevulinate ‘blue light’ fluorescence cystoscopy in the investigation of clinically unconfirmed positive urine cytology by Ray, Eleanor R., Chatterton, Kathryn, Khan, Mohammed S., Thomas, Kay, Chandra, Ashish, O’Brien, Tim S.

“…OBJECTIVE To investigate the value of photodynamic diagnosis (PDD) using hexylaminolaevulinate (Hexvix®, PhotoCure, Oslo, Norway) in the investigation of…”
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A strategic vision for BAUS by O’Brien, Tim

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MP70-05 PREDICTORS OF OPEN CONVERSION DURING MINIMALLY INVASIVE RENAL SURGERY IN ENGLAND by Nair, Rajesh, Gray, Robert, Anderson, Christopher J, Fowler, Sarah, O'Brien, Tim S, Le Roux, Pieter J

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Ultrathin self-assembled fibrin sheets by O'Brien, E. Tim III, Falvo, Michael R, Millard, Daniel, Eastwood, Brian, Taylor, Russell M. II, Superfine, Richard

“…Fibrin polymerizes into the fibrous network that is the major structural component of blood clots and thrombi. We demonstrate that fibrin from three different…”
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