Search Results - "Tilve, Santosh G."

Recent Developments in the Synthesis of Five- and Six-Membered Heterocycles Using Molecular Iodine by Parvatkar, Prakash T., Parameswaran, Perunninakulath S., Tilve, Santosh G.

“…Heterocyclic scaffolds represent the key structural subunits of many biologically active compounds. Over the last few years iodine‐mediated reactions have been…”
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Domino Bischler–Napieralski – Michael Reaction and Oxidation – New Route to Coumarin‐Pyrrole‐Isoquinoline Fused Pentacycles by Mandrekar, Ketan S., Kadam, Hari K., Tilve, Santosh G.

“…Lamellarin scaffold is synthesized by a metal free convergent route involving domino Bischler–Napieralski reaction – Michael reaction – oxidation sequence. Six…”
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An efficient synthesis of indoloquinoline alkaloid—neocryptolepine (cryptotackieine) by Parvatkar, Prakash T., Tilve, Santosh G.

“…A short and convenient method for the synthesis of neocryptolepine (cryptotackieine) is described using Wittig reaction and one-pot…”
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Total Synthesis of (−)- and (+)-Tedanalactam by Majik, Mahesh S, Parameswaran, Perunninakulath S, Tilve, Santosh G

“…The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic…”
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Synthetic access to thiolane-based therapeutics and biological activity studies by Rodrigues, Lima, Tilve, Santosh G., Majik, Mahesh S.

“…Secondary metabolites isolated from bioactive extracts of natural sources iteratively pioneer the research in drug discovery. Modern medicine is often inspired…”
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Iodine-Mediated Intramolecular Dehydrogenative Coupling: Synthesis of N‑Alkylindolo[3,2‑c]- and -[2,3‑c]quinoline Iodides by Volvoikar, Prajesh S, Tilve, Santosh G

“…An I2/TBHP-mediated intramolecular dehydrogenative coupling reaction is developed for the synthesis of a library of medicinally important…”
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P4O10/TfOH mediated domino condensation–cyclization of amines with diacids: a route to indolizidine alkaloids under catalyst- and solvent-free conditions by Mandrekar, Ketan S, Tilve, Santosh G

“…A domino condensation–cyclization method is developed to synthesize indolizidine alkaloids using a P4O10/TfOH reagent system without the employment of either a…”
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Intramolecular Diels–Alder reaction as a key step in tandem or sequential processes: a versatile tool for the synthesis of fused and bridged bicyclic or polycyclic compounds by Parvatkar, Prakash T., Kadam, Hari K., Tilve, Santosh G.

“…[Display omitted]…”
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Graphite catalyzed solvent free synthesis of dihydropyrimidin-2(1H)-ones/thiones and their antidiabetic activity by Dhumaskar, Kashinath L, Meena, Surya Nandan, Ghadi, Sanjeev C, Tilve, Santosh G

“…A solvent free three component condensation reaction between an aldehyde, ethyl acetoacetate and urea catalyzed by graphite, a green catalyst is described for…”
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α-Glucosidase inhibition activity and in silico study of 2-(benzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one, a synthetic derivative of flavone by Meena, Surya N., kumar, Ujjwal, Naik, Mayuri M., Ghadi, Sanjeev C., Tilve, Santosh G.

“…[Display omitted] •BDC, a flavone derivative showed 22.4 fold higher enzyme inhibition than acarbose.•During the enzyme kinetic study BDC showed…”
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Synthetic access to syn-functionalised chiral hydroxy pyrrolidines and pyrrolidones: Evaluation of α-glucosidase inhibition activity, docking studies and pharmacokinetics prediction by Mhaldar, Shashank N., Kotkar, Gayatri D., Tilve, Santosh G.

“…[Display omitted] •New chiral hydroxy pyrrolidines and pyrrolidones are synthesized via cross aldol reaction.•The hydroxy pyrrolidines are more potent than…”
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An Alternate Synthesis of 6H-Indolo[2,3-b]quinoline via One-Pot Alkylation-Dehydration-Cyclization-Aromatization Approach by Kadam, Hari K., Tilve, Santosh G.

“…A simple, straightforward and efficient synthesis of 6H‐indolo[2,3‐b]quinoline, a natural product isolated from leaves of Justicia betonica, is achieved…”
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Synthesis of (−)-hygrine, (−)-norhygrine, (−)-pseudohygroline and (−)-hygroline via Nef reaction by Bhat, Chinmay, Tilve, Santosh G.

“…Synthesis of tropane alkaloids (−)-hygrine, (−)-norhygrine and sedum alkaloids (−)-pseudohygroline and (−)-hygroline is described from l-proline via Henry and…”
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Graphite catalyzed green synthesis of quinoxalines by Kadam, Hari K., Khan, Salman, Kunkalkar, Rupesh A., Tilve, Santosh G.

“…A new simple approach using environmentally benign, cheap, and easily recyclable graphite as a heterogeneous catalyst for the synthesis of quinoxalines is…”
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Pyrrolidine and iodine catalyzed domino aldol-Michael-dehydrogenative synthesis of flavones by Naik, Mayuri M., Tilve, Santosh G., Kamat, Vijayendra P.

“…A one pot synthesis of flavones is established from 2′-hydroxyacetophenones and substituted aromatic aldehydes. The method uses domino aldol-Michael-oxidation…”
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Molecular iodine catalyst promoted synthesis of chromans and 4-aryl-3,4-dihydrobenzopyran-2-ones via [3+3] cyclocoupling by Naik, Mayuri M., Kamat, Durga P., Tilve, Santosh G., Kamat, Vijayendra P.

“…Molecular iodine as an inexpensive catalyst is described in the construction of 2-substituted or 2,2-disubstituted chromans and…”
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Tandem approaches for the synthesis of functionalized pyrrolidones: efficient routes toward allokainic acid and kainic acid by Bhat, Chinmay, Tilve, Santosh G.

“…Tandem approaches for the synthesis of pyrrolidone precursor of allokainic acid and kainic acid are described. The synthesis of pyrrolidone intermediate of…”
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An Expeditious I2-Catalyzed Entry into 6H-Indolo[2,3-b]quinoline System of Cryptotackieine by Parvatkar, Prakash T, Parameswaran, Perunninakulath S, Tilve, Santosh G

“…A synthesis of a series of novel 6H-indolo[2,3-b]quinolines with different substituents on the quinoline ring is described. The method involves reaction of…”
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Convenient and efficient syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal by Kurangi, Reshma F, Tilve, Santosh G, Blair, Ian A

“…Lipid peroxidation products 4-hydroxy-2(E)-nonenal (HNE) and 4-oxo-2(E)-nonenal (ONE) were conveniently synthesized using Wittig and Horner-Wardsworth-Emmons…”
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Solventless Mechanosynthesis Of Bis(Indolyl)Methanes by Mhaldar, Shashank N., Mandrekar, Ketan S., Gawde, Mukund K., Shet, Rajdatt V., Tilve, Santosh G.

“…Ball-milling technique as a solvent-free and an alternative green process was investigated for the eco-benign synthesis of bis(indolyl)methanes (BIMs) from…”
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