Search Results - "Tilunaite, Agne"
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Ca2+ Release via IP3 Receptors Shapes the Cardiac Ca2+ Transient for Hypertrophic Signaling
Published in Biophysical journal (15-09-2020)“…Calcium (Ca2+) plays a central role in mediating both contractile function and hypertrophic signaling in ventricular cardiomyocytes. L-type Ca2+ channels…”
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2
IP3R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca2+]
Published in Mathematical biosciences (01-01-2023)“…Calcium (Ca2+) plays a critical role in the excitation contraction coupling (ECC) process that mediates the contraction of cardiomyocytes during each…”
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Journal Article -
3
A Bayesian approach to modelling heterogeneous calcium responses in cell populations
Published in PLoS computational biology (01-10-2017)“…Calcium responses have been observed as spikes of the whole-cell calcium concentration in numerous cell types and are essential for translating extracellular…”
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Journal Article -
4
Detecting RyR Clusters with CaCLEAN: Validation and Influence of Spatial Heterogeneity
Published in Biophysical journal (01-02-2019)Get full text
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5
InsP3R-RyR channel crosstalk augments sarcoplasmic reticulum Ca2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-06-2023)“…Ca2+ transients (CaT) underlying cardiomyocyte (CM) contraction require efficient Ca2+ coupling between sarcolemmal Ca2+ channels and sarcoplasmic reticulum…”
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6
Probabilistic encoding of stimulus strength in astrocyte global calcium signals
Published in Glia (01-04-2016)“…Astrocyte calcium signals can range in size from subcellular microdomains to waves that spread through the whole cell (and into connected cells). The…”
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Journal Article -
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InsP 3 R-RyR channel crosstalk augments sarcoplasmic reticulum Ca 2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-06-2023)“…Ca transients (CaT) underlying cardiomyocyte (CM) contraction require efficient Ca coupling between sarcolemmal Ca channels and sarcoplasmic reticulum (SR)…”
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Journal Article -
8
Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release
Published in Frontiers in physiology (02-10-2019)“…Calcium signaling plays a pivotal role in cardiomyocytes, coupling electrical excitation to mechanical contraction of the heart. Determining locations of…”
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Journal Article -
9
Ca2+ release via IP3 receptors shapes the cytosolic Ca2+ transient for hypertrophic signalling in ventricular cardiomyocytes
Published 17-08-2020“…Calcium (Ca2+) plays a central role in mediating both contractile function and hypertrophic signalling in ventricular cardiomyocytes. L-type Ca2+ channels…”
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Journal Article -
10
Modelling of intracellular calcium dynamics
Published 01-01-2018“…Ca2+ as a universal messenger participates in a great variety of physiological functions and biological events such as cell maturation, chemotaxis or gene…”
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Dissertation -
11
IP 3 R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca 2+ ]
Published in Mathematical biosciences (01-01-2023)“…Calcium (Ca ) plays a critical role in the excitation contraction coupling (ECC) process that mediates the contraction of cardiomyocytes during each heartbeat…”
Get full text
Journal Article -
12
Ca 2+ Release via IP 3 Receptors Shapes the Cardiac Ca 2+ Transient for Hypertrophic Signaling
Published in Biophysical journal (15-09-2020)“…Calcium (Ca ) plays a central role in mediating both contractile function and hypertrophic signaling in ventricular cardiomyocytes. L-type Ca channels trigger…”
Get full text
Journal Article