Search Results - "Tillman, Brittany"

Increased activity of the complement system in the liver of patients with alcoholic hepatitis by Shen, Hong, French, Barbara A., Liu, Hui, Tillman, Brittany C., French, Samuel W.

“…Inflammation has been suggested as a mechanism underlying the development of alcoholic hepatitis (AH). The activation of the complement system plays an…”
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Role of Protein Quality Control Failure in Alcoholic Hepatitis Pathogenesis by French, Samuel W, Masouminia, Maryam, Samadzadeh, Sara, Tillman, Brittany C, Mendoza, Alejandro, French, Barbara A

“…The mechanisms of protein quality control in hepatocytes in cases of alcoholic hepatitis (AH) including ufmylation, FAT10ylation, metacaspase 1 (Mca1), ERAD…”
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Increased DNA methylation in the livers of patients with alcoholic hepatitis by Shen, Hong, French, Barbara A., Tillman, Brittany C., Li, Jun, French, Samuel W.

“…Epigenetic regulation of gene expression has been suggested to play a critical role in the development of alcoholic hepatitis (AH). Although it has been shown…”
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Alcoholic and non-alcoholic steatohepatitis by Neuman, Manuela G., French, Samuel W., French, Barbara A., Seitz, Helmut K., Cohen, Lawrence B., Mueller, Sebastian, Osna, Natalia A., Kharbanda, Kusum K., Seth, Devanshi, Bautista, Abraham, Thompson, Kyle J., McKillop, Iain H., Kirpich, Irina A., McClain, Craig J., Bataller, Ramon, Nanau, Radu M., Voiculescu, Mihai, Opris, Mihai, Shen, Hong, Tillman, Brittany, Li, Jun, Liu, Hui, Thomes, Paul G., Ganesan, Murali, Malnick, Steve

“…This paper is based upon the “Charles Lieber Satellite Symposia” organized by Manuela G. Neuman at the Research Society on Alcoholism (RSA) Annual Meetings,…”
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Methylation and Gene Expression Responses to Ethanol Feeding and Betaine Supplementation in the Cystathionine Beta Synthase-Deficient Mouse by Medici, Valentina, Schroeder, Diane I., Woods, Rima, LaSalle, Janine M., Geng, Yongzhi, Shibata, Noreene M., Peerson, Janet, Hodzic, Emir, Dayal, Sanjana, Tsukamoto, Hidekazu, Kharbanda, Kusum K., Tillman, Brittany, French, Samuel W., Halsted, Charles H.

“…Background Alcoholic steatohepatitis (ASH) is caused in part by the effects of ethanol (EtOH) on hepatic methionine metabolism. Methods To investigate the…”
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Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research by Neuman, Manuela G, Seitz, Helmut Karl, French, Samuel W, Malnick, Stephen, Tsukamoto, Heidekazu, Cohen, Lawrence B, Hoffman, Paula, Tabakoff, Boris, Fasullo, Michael, Nagy, Laura E, Tuma, Pamela L, Schnabl, Bernd, Mueller, Sebastian, Groebner, Jennifer L, Barbara, French A, Yue, Jia, Nikko, Afifiyan, Alejandro, Mendoza, Brittany, Tillman, Edward, Vitocruz, Harrall, Kylie, Saba, Laura, Mihai, Opris

“…The following review article presents clinical and experimental features of alcohol-induced liver disease (ALD). Basic aspects of alcohol metabolism leading to…”
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Different roles of FAT10, FOXO1, and ADRA2A in hepatocellular carcinoma tumorigenesis in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH) by Jia, Yue, French, Barbara, Tillman, Brittany, French, Samuel

“…Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer related deaths worldwide. Among others, non-alcoholic…”
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Different Roles of Epigenetic Regulators and Inflammasome in Hepatocellular Carcinoma Tumorigenesis in Patients with ASH vs. NASH by Jia, Yue, Ji, Ping, Nguyen, Luan, French, Barbara, Tillman, Brittany, French, Sameul W

“…As the fifth most common cancer and the second leading cause of cancer related deaths worldwide, hepatocellular carcinoma (HCC) is an aggressive tumor type…”
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Alcoholic versus Non‐alcoholic Steatohepatitis: Levels of Expression of Some Proteins Involved in Tumorigenesis by Nguyen, Luan, Masouminia, Maryam, Mendoza, Alejandro, Samadzadeh, Sara, Tillman, Brittany, French, Barbara, French, Samuel

“…Non‐alcoholic steatohepatitis (NASH) is commonly associated with obesity, type 2 diabetes, and/or hypertriglyceridemia, while alcoholic steatohepatitis (ASH)…”
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Overexpression of MHCII by hepatocytes in Alcoholic Hepatitis (AH) compared to Non-alcoholic Steatohepatitis (NASH) and normal controls by Lu, Jiajie G, Iyasu, Askalu, French, Barbara, Tillman, Brittany, French, Samuel W, M.D

“…AbstractPreviously we have shown that in autoimmune hepatitis CD4 positive lymphocytes form an immunologic synapse with hepatocytes, leading to gradual…”
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Increased activity of the complement system in the liver of patients with alcoholic hepatitis by Shen, Hong, French, Barbara, Liu, Hui, Tillman, Brittany, French, Samuel

“…Abstract only Inflammation has been suggested as a mechanism underlying the development of alcoholic hepatitis (AH). The activation of the complement system…”
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BRCA1‐Mediated DNA Damage Response is a Potential Player Involved in Mallory‐Denk Body (MDB) Formation in Alcoholic Hepatitis (AH) by Liu, Hui, French, Barbara, Li, Jun, Tillman, Brittany, French, Samuel

“…Abstract only…”
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Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro by Oliva, Joan, Bardag-Gorce, Fawzia, Tillman, Brittany, French, Samuel W.

“…There is a need for a nontoxic antioxidant agent to be identified which will prevent alcoholic liver disease (ALD) in alcoholic patients. We tested 4 candidate…”
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Up regulation of Spleen Tyrosine Kinase in ballooned hepatocytes with Mallory‐Denk Bodies in Alcoholic Liver Disease by Afifiyan, Nikoo, Samadzadeh, Sara, Masouminia, Maryam, Tillman, Brittany, French, Barbara A., French, Samuel W.

“…Abstract only Liver injury from alcohol abuse causes balloon hepatocytes and MDB formation. Mallory‐Denk bodies (MDBs) are found in 70% to 75% of patients with…”
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Expression of Miscellaneous Genes Upregulated in Hepatocellular Carcinoma in Patients with Alcoholic (ASH) and Non‐alcoholic Steatohepatitis (NASH) by Lu, Jiajie, Nguyen, Luan, Samadzadeh, Sara, Masouminia, Maryam, Mendoza, Alejandro, Tillman, Brittany, Morgan, Timothy, French, Barbara, French, Samuel

“…Both non‐alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis (ASH) can lead to cirrhosis and hepatocellular carcinoma. However, the rate of…”
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The different expression of tumor suppressors, RASSF1A, RUNX3, and GSTP1, in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH) by Jia, Yue, Ji, Ping, French, Barbara, Tillman, Brittany, French, Samuel W.

“…As the fifth most common cancer and the second leading cause of cancer related deaths worldwide, hepatocellular carcinoma (HCC) causes up to one million deaths…”
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Alcoholic hepatitis versus non-alcoholic steatohepatitis: Levels of expression of some proteins involved in tumorigenesis by Nguyen, Luan, Masouminia, Maryam, Mendoza, Alejandro, Samadzadeh, Sara, Tillman, Brittany, Morgan, Timothy, French, Barbara, French, Samuel

“…Non-alcoholic steatohepatitis (NASH) is commonly associated with obesity, type 2 diabetes, and/or hypertriglyceridemia, while alcoholic steatohepatitis (ASH)…”
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Mallory–Denk Body (MDB) formation modulates ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH) by Liu, Hui, Gong, Ming, French, Barbara A., Li, Jun, Tillman, Brittany, French, Samuel W.

“…Promoter CpG island hypermethylation is an important mechanism for inactivating key cellular enzymes that mediate epigenetic processes in hepatitis-related…”
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Altered regulation of miR-34a and miR-483-3p in alcoholic hepatitis and DDC fed mice by Liu, Hui, French, Barbara A., Li, Jun, Tillman, Brittany, French, Samuel W.

“…MicroRNAs are small noncoding RNAs that negatively regulate gene expression by binding to the untranslated regions of their target mRNAs. Deregulation of…”
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TLR3/4 signaling is mediated via the NFκB-CXCR4/7 pathway in human alcoholic hepatitis and non-alcoholic steatohepatitis which formed Mallory–Denk bodies by Liu, Hui, Li, Jun, Tillman, Brittany, Morgan, Timothy R., French, Barbara A., French, Samuel W.

“…Activation of Toll-like receptor (TLR) signaling which stimulates inflammatory and proliferative pathways is the key element in the pathogenesis of…”
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