Search Results - "Tildesley, Michael J"
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Modelling optimal vaccination strategy for SARS-CoV-2 in the UK
Published in PLoS computational biology (01-05-2021)“…The COVID-19 outbreak has highlighted our vulnerability to novel infections. Faced with this threat and no effective treatment, in line with many other…”
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Identification of dynamical changes of rabies transmission under quarantine: Community-based measures towards rabies elimination
Published in PLoS computational biology (01-12-2023)“…Quarantine has been long used as a public health response to emerging infectious diseases, particularly at the onset of an epidemic when the infected…”
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Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristics
Published in Nature communications (30-09-2021)“…Viral reproduction of SARS-CoV-2 provides opportunities for the acquisition of advantageous mutations, altering viral transmissibility, disease severity,…”
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Predictions of COVID-19 dynamics in the UK: Short-term forecasting and analysis of potential exit strategies
Published in PLoS computational biology (22-01-2021)“…Efforts to suppress transmission of SARS-CoV-2 in the UK have seen non-pharmaceutical interventions being invoked. The most severe measures to date include all…”
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Modelling the impact of non-pharmaceutical interventions on the spread of COVID-19 in Saudi Arabia
Published in Scientific reports (16-01-2023)“…Countries around the world have implemented a series of interventions to contain the pandemic of coronavirus disease (COVID-19), and significant lessons can be…”
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Comparison of the 2021 COVID-19 roadmap projections against public health data in England
Published in Nature communications (22-08-2022)“…Control and mitigation of the COVID-19 pandemic in England has relied on a combination of vaccination and non-pharmaceutical interventions (NPIs). Some of…”
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Prospects for detecting early warning signals in discrete event sequence data: Application to epidemiological incidence data
Published in PLoS computational biology (01-09-2020)“…Early warning signals (EWS) identify systems approaching a critical transition, where the system undergoes a sudden change in state. For example, monitoring…”
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Assessing the impact of lateral flow testing strategies on within-school SARS-CoV-2 transmission and absences: A modelling study
Published in PLoS computational biology (01-05-2022)“…Rapid testing strategies that replace the isolation of close contacts through the use of lateral flow device tests (LFTs) have been suggested as a way of…”
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Quantifying pupil-to-pupil SARS-CoV-2 transmission and the impact of lateral flow testing in English secondary schools
Published in Nature communications (01-03-2022)“…A range of measures have been implemented to control within-school SARS-CoV-2 transmission in England, including the self-isolation of close contacts and twice…”
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The impact of school reopening on the spread of COVID-19 in England
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-07-2021)“…By mid-May 2020, cases of COVID-19 in the UK had been declining for over a month; a multi-phase emergence from lockdown was planned, including a scheduled…”
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When should lockdown be implemented? Devising cost-effective strategies for managing epidemics amid vaccine uncertainty
Published in PLoS computational biology (18-07-2024)“…During an infectious disease outbreak, public health policy makers are tasked with strategically implementing interventions whilst balancing competing…”
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Adaptive management and the value of information: learning via intervention in epidemiology
Published in PLoS biology (01-10-2014)“…Optimal intervention for disease outbreaks is often impeded by severe scientific uncertainty. Adaptive management (AM), long-used in natural resource…”
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Modelling the Influence of Climate and Vector Control Interventions on Arbovirus Transmission
Published in Viruses (30-07-2024)“…Most mathematical models that assess the vectorial capacity of disease-transmitting insects typically focus on the influence of climatic factors to predict…”
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An analysis of school absences in England during the COVID-19 pandemic
Published in BMC medicine (07-06-2021)“…The introduction of SARS-CoV-2, the virus that causes COVID-19 infection, in the UK in early 2020, resulted in the introduction of several control policies to…”
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Modelling seasonality of Lassa fever incidences and vector dynamics in Nigeria
Published in PLoS neglected tropical diseases (01-11-2023)“…Lassa fever (Lf) is a viral haemorrhagic disease endemic to West Africa and is caused by the Lassa mammarenavirus . The rodent Mastomys natalensis serves as…”
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Real-time decision-making during emergency disease outbreaks
Published in PLoS computational biology (01-07-2018)“…In the event of a new infectious disease outbreak, mathematical and simulation models are commonly used to inform policy by evaluating which control strategies…”
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A network modelling approach to assess non-pharmaceutical disease controls in a worker population: An application to SARS-CoV-2
Published in PLoS computational biology (01-06-2021)“…As part of a concerted pandemic response to protect public health, businesses can enact non-pharmaceutical controls to minimise exposure to pathogens in…”
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Modelling African horse sickness emergence and transmission in the South African control area using a deterministic metapopulation approach
Published in PLoS computational biology (06-09-2023)“…African horse sickness is an equine orbivirus transmitted by Culicoides Latreille biting midges. In the last 80 years, it has caused several devastating…”
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A comparative analysis of epidemiological characteristics of MERS-CoV and SARS-CoV-2 in Saudi Arabia
Published in Infectious disease modelling (01-09-2022)“…In this study, we determine and compare the incubation duration, serial interval, pre-symptomatic transmission, and case fatality rate of MERS-CoV and COVID-19…”
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Modeling Treatment Strategies to Inform Yaws Eradication
Published in Emerging infectious diseases (01-11-2020)“…Yaws is a neglected tropical disease targeted for eradication by 2030. To achieve eradication, finding and treating asymptomatic infections as well as clinical…”
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