Search Results - "Tikhonenko, A T"

Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation by TIKHONENKO, A. T, HARTMAN, A.-R, LINIAL, M. L

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Transforming variants of the avian myc-containing retrovirus FH3 arise prior to phenotypic selection by TIKHONENKO, A. T, LINIAL, M. L

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Gag as well as myc sequences contribute to the transforming phenotype of the avian retrovirus FH3 by Tikhonenko, A.T. (Fred Hutchinson Cancer Research Center, Seattle, WA), Linial, M.L

“…The avian retrovirus FH3, like MC29 and CMII, encodes a Gag-Myc fusion protein. However, the FH3-encoded protein is larger, about 145 kDa, and contains almost…”
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Viral Myc Oncoproteins in Infected Fibroblasts Down-modulate Thrombospondin-1, a Possible Tumor Suppressor Gene by Tikhonenko, Andrei T., Black, Daniel J., Linial, Maxine L.

“…We are interested in identifying the transcriptional targets of the Myc oncoproteins. To this end, we have fused Myc of the MC29 retrovirus with the rat…”
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Genetic structure of the endogenous proviruses and expression of the gag gene in Brown Leghorn chickens by Gudkov, A V, Korec, E, Chernov, M V, Tikhonenko, A T, Obukh, I B, Hlozánek, I

“…Seven loci of endogenous proviruses were detected in the genome of Brown Leghorn chickens. Sets of endogenous proviruses in DNA of the chicken embryos examined…”
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Methylation of endogenous proviruses of Brown Leghorn chickens by Gudkov, A V, Chernov, M V, Tikhonenko, A T, Obukh, I B, Hlozánek, I

“…Among the 7 endogenous proviruses we have detected in Brown Leghorn chickens none encodes the production of virions and only one, ev-3, expresses the gag gene…”
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v-Myc is invariably required to sustain rapid proliferation of infected cells but in stable cell lines becomes dispensable for other traits of the transformed phenotype by Tikhonenko, A T, Black, D J, Linial, M L

“…The v-myc-containing retrovirus MC29 induces neoplastic transformation of avian embryo cells. To determine which traits of the transformed phenotype are…”
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Avian endogenous provirus (ev-3) env gene sequencing: implication for pathogenic retrovirus origination by Tikhonenko, A T, Lomovskaya, O L

“…The avian endogenous env gene product blocks the surface receptor and, as a result, cells become immune to related exogenous retroviruses. On the other hand,…”
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Long terminal repeats of dwarf hamster endogenous retrovirus are highly diverged and do not maintain efficient transcription by Tikhonenko, A T, Polotskaya, A V, Vassetzky, 3rd, N S, Golovkina, T V, Gudkov, A V

“…Recently we described a new endogenous proretrovirus of dwarf hamster Phodopus sungorus (MRS-Ps). Its sequence possesses evident homology with the endonuclease…”
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Molecular cloning and primary structure analysis of the mouse mammary tumor virus-related element from dwarf hamster genome by Tikhonenko, A T, Vassetzky, 3rd, N S, Golovkina, T V, Gudkov, A V

“…Eleven recombinant bacteriophages carrying mouse mammary tumor virus (MMTV)-related sequences (MRS) were isolated from the genomic library of the dwarf hamster…”
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Endogenous proretroviruses and other autonomous retroposons: traces of viral origin or decay? by Tikhonenko, A T, Gudkov, A V

“…Origin of viruses is considered to be a fundamental trend in biology. In 1970 H. Temin proposed that some of them (namely, retroviruses) could originate from…”
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Sequences homologous to mouse mammary cancer virus are common in mammalian and avian genomes by Golovkina, T V, Tikhonenko, A T, Vasetskiĭ, N S, Sheftel', B I, Gudkov, A V

“…Sequences distantly related to mouse mammary tumor virus (MRS) were found in a wide range of mammalian genomes using blot hybridization. The number of MRS…”
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Cloning and analysis of the primary structure of an element, related to the murine mammary cancer virus, from the genome of the Djungarian hamster by Vasetskiĭ, N S, Tikhonenko, A T, Golovkina, T V, Gudkov, A V

“…11 recombinant bacteriophages from the genomic library of Djungarian hamster genome, that carry MMTV-related sequences (MRS-Ps), have been cloned with the…”
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Distribution of mouse mammary tumor virus-related sequences does not correlate with the taxonomic position of their hosts by Golovkina, T V, Tikhonenko, A T, Vassetzky, 3rd, N S, Sheftel, B I, Gudkov, A V

“…Sequences (MRS) distantly related to mouse mammary tumor virus (MMTV) were found in genomes of a wide range of mammalian species using blot hybridization. The…”
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The genome of chickens free of endogenous avian leukosis-sarcoma proviruses contains sequences distantly related to Rous sarcoma virus by Chernov, M V, Tikhonenko, A T, Zaĭtsevskaia, T E, Denisova, R A, Obukh, I B

“…Line of Brown leghorn chickens free of RAV-O-type endogenous proviruses was obtained by selection under blot hybridization control. A set of dispersed…”
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Possible mechanisms of the occurrence of new loci of defective endogenous proviruses by Tikhonenko, A T, Chernov, M V, Obukh, I B, Gudkov, A V

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