Search Results - "Tijhuis, Johan"
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The Identification of Small Molecule Inhibitors That Reduce Invasion and Metastasis of Aggressive Cancers
Published in International journal of molecular sciences (08-02-2021)“…Transformed epithelial cells can activate programs of epithelial plasticity and switch from a sessile, epithelial phenotype to a motile, mesenchymal phenotype…”
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ChemStable: a web server for rule-embedded naïve Bayesian learning approach to predict compound stability
Published in Journal of computer-aided molecular design (01-09-2014)“…Predicting compound chemical stability is important because unstable compounds can lead to either false positive or to false negative conclusions in bioassays…”
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Abstract 3768: Targeting of epithelial-to-mesenchyme transition by a novel small molecule inhibitor attenuates prostate and breast cancer invasiveness and bone metastases
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Transformed epithelial cells can activate embryonic programs of epithelial plasticity and switch from a sessile, epithelial phenotype to a motile, mesenchymal…”
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COMDECOM: predicting the lifetime of screening compounds in DMSO solution
Published in Journal of biomolecular screening (01-06-2009)“…The technological evolution of the 1990s in both combinatorial chemistry and high-throughput screening created the demand for rapid access to the compound deck…”
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