Search Results - "Tijeras‐Raballand, Annemilaï"

Macrophages in the microenvironment of head and neck cancer: potential targets for cancer therapy by Evrard, Diane, Szturz, Petr, Tijeras-Raballand, Annemilaï, Astorgues-Xerri, Lucile, Abitbol, Chloé, Paradis, Valérie, Raymond, Eric, Albert, Sébastien, Barry, Béatrix, Faivre, Sandrine

“…[Display omitted] •Macrophages are frequently reported in the microenvironment of head and neck cancers.•Macrophages may harbor two phenotypes: antitumoral M1…”
Get full text

Targeting the Ras–ERK pathway in pancreatic adenocarcinoma by Neuzillet, Cindy, Hammel, Pascal, Tijeras-Raballand, Annemilaï, Couvelard, Anne, Raymond, Eric

“…Pancreatic ductal adenocarcinoma (PAC) stands as the poorest prognostic tumor of the digestive tract with limited therapeutic options. PAC carcinogenesis is…”
Get full text

Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib by Serova, Maria, Tijeras-Raballand, Annemilaï, Dos Santos, Celia, Martinet, Matthieu, Neuzillet, Cindy, Lopez, Alfred, Mitchell, Dianne C, Bryan, Brad A, Gapihan, Guillaume, Janin, Anne, Bousquet, Guilhem, Riveiro, Maria Eugenia, Bieche, Ivan, Faivre, Sandrine, Raymond, Eric, de Gramont, Armand

“…Angiogenesis is hallmark of clear cell renal cell carcinogenesis. Anti-angiogenic therapies have been successful in improving disease outcome; however, most…”
Get full text

Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma by Neuzillet, Cindy, Tijeras‐Raballand, Annemilaï, Ragulan, Chanthirika, Cros, Jérôme, Patil, Yatish, Martinet, Matthieu, Erkan, Mert, Kleeff, Jörg, Wilson, Jeremy, Apte, Minoti, Tosolini, Marie, Wilson, Abigail S, Delvecchio, Francesca R, Bousquet, Corinne, Paradis, Valérie, Hammel, Pascal, Sadanandam, Anguraj, Kocher, Hemant M

“…Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain…”
Get full text

Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study by André, Thierry, de Gramont, Armand, Vernerey, Dewi, Chibaudel, Benoist, Bonnetain, Franck, Tijeras-Raballand, Annemilaï, Scriva, Aurelie, Hickish, Tamas, Tabernero, Josep, Van Laethem, Jean Luc, Banzi, Maria, Maartense, Eduard, Shmueli, Einat, Carlsson, Goran U, Scheithauer, Werner, Papamichael, Demetris, Möehler, Marcus, Landolfi, Stefania, Demetter, Pieter, Colote, Soudhir, Tournigand, Christophe, Louvet, Christophe, Duval, Alex, Fléjou, Jean-François, de Gramont, Aimery

“…The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer) study has demonstrated 3-year…”
Get full text

Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma by Neuzillet, Cindy, Nicolle, Rémy, Raffenne, Jérôme, Tijeras‐Raballand, Annemilaï, Brunel, Alexia, Astorgues‐Xerri, Lucile, Vacher, Sophie, Arbateraz, Floriane, Fanjul, Marjorie, Hilmi, Marc, Samain, Rémi, Klein, Christophe, Perraud, Aurélie, Rebours, Vinciane, Mathonnet, Muriel, Bièche, Ivan, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne

“…Cancer‐associated fibroblasts (CAFs) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Previously we described four CAF…”
Get full text

Unraveling galectin-1 as a novel therapeutic target for cancer by Astorgues-Xerri, Lucile, Riveiro, Maria E, Tijeras-Raballand, Annemilaï, Serova, Maria, Neuzillet, Cindy, Albert, Sébastien, Raymond, Eric, Faivre, Sandrine

“…Summary Galectins belong to a family of carbohydrate-binding proteins with an affinity for β-galactosides. Galectin-1 is differentially expressed by various…”
Get full text

State of the art and future directions of pancreatic ductal adenocarcinoma therapy by Neuzillet, Cindy, Tijeras-Raballand, Annemilaï, Bourget, Philippe, Cros, Jérôme, Couvelard, Anne, Sauvanet, Alain, Vullierme, Marie-Pierre, Tournigand, Christophe, Hammel, Pascal

“…Pancreatic ductal adenocarcinoma (PDAC) is expected to become the second cause of cancer-related death in 2030. PDAC is the poorest prognostic tumor of the…”
Get full text

Stromal expression of SPARC in pancreatic adenocarcinoma by Neuzillet, Cindy, Tijeras-Raballand, Annemilaï, Cros, Jérôme, Faivre, Sandrine, Hammel, Pascal, Raymond, Eric

“…Pancreatic ductal adenocarcinoma (PDAC) stands as the poorest prognostic tumor of the digestive tract, with a 5-year survival rate of less than 5 %…”
Get full text

Targeting cancer cell metabolism in pancreatic adenocarcinoma by Cohen, Romain, Neuzillet, Cindy, Tijeras-Raballand, Annemilaï, Faivre, Sandrine, de Gramont, Armand, Raymond, Eric

“…Pancreatic ductal adenocarcinoma (PDAC) is expected to become the second leading cause of cancer death by 2030. Current therapeutic options are limited,…”
Get full text

Pancreatic cancer orthotopic graft in a murine model by Muzzolini, Milena, Belhabib, Ismahane, Cardot, Victoire, Tijeras-Raballand, Annemilaï, Neuzillet, Cindy, Bousquet, Corinne, Lupinacci, Renato Micelli, Jean, Christine

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with increasing incidence. Even if progress have been made, the five-year overall…”
Get full text

Netrin-4 Delays Colorectal Cancer Carcinomatosis by Inhibiting Tumor Angiogenesis by Eveno, Clarisse, Broqueres-You, Dong, Feron, Jean-Guillaume, Rampanou, Aurore, Tijeras-Raballand, Annemilaï, Ropert, Stanislas, Leconte, Laurence, Levy, Bernard I, Pocard, Marc

“…A close relationship between tumor angiogenesis, growth, and carcinomatosis has been observed. Netrin-4 (NT-4) has been shown to regulate angiogenic responses…”
Get full text

High c-Met expression in stage I-II pancreatic adenocarcinoma: proposal for an immunostaining scoring method and correlation with poor prognosis by Neuzillet, Cindy, Couvelard, Anne, Tijeras-Raballand, Annemilaï, de Mestier, Louis, de Gramont, Armand, Bédossa, Pierre, Paradis, Valérie, Sauvanet, Alain, Bachet, Jean-Baptiste, Ruszniewski, Philippe, Raymond, Eric, Hammel, Pascal, Cros, Jérôme

“…Aims c‐Met is an emerging biomarker in pancreatic ductal adenocarcinoma (PDAC); there is no consensus regarding the immunostaining scoring method for this…”
Get full text

Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib by Serova, Maria, de Gramont, Armand, Tijeras-Raballand, Annemilaï, Dos Santos, Célia, Riveiro, Maria Eugenia, Slimane, Khemaies, Faivre, Sandrine, Raymond, Eric

“…Purpose To evaluate first-generation rapamycin analogs (everolimus, temsirolimus, and rapamycin) and second-generation drugs inhibiting mTOR kinase (AZD-8055),…”
Get full text

Targeting the TGFβ pathway for cancer therapy by Neuzillet, Cindy, Tijeras-Raballand, Annemilaï, Cohen, Romain, Cros, Jérôme, Faivre, Sandrine, Raymond, Eric, de Gramont, Armand

“…The TGFβ signaling pathway has pleiotropic functions regulating cell growth, differentiation, apoptosis, motility and invasion, extracellular matrix…”
Get full text

MEK in cancer and cancer therapy by NEUZILLET, Cindy, TIJERAS-RABALLAND, Annemilaï, DE MESTIER, Louis, CROS, Jérôme, FAIVRE, Sandrine, RAYMOND, Eric

“…The mitogen-activated extracellular signal-regulated kinase (MEK) pathway is one of the best-characterized kinase cascades in cancer cell biology. It is…”
Get full text

Biomarkers in Hepatobiliary Cancers: What Is Useful in Clinical Practice? by Boilève, Alice, Hilmi, Marc, Delaye, Matthieu, Tijeras-Raballand, Annemilaï, Neuzillet, Cindy

“…Hepatocellular carcinoma (HCC) and biliary tract cancers (BTC) exhibit a poor prognosis with 5-year overall survival rates around 15%, all stages combined…”
Get full text

Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas by Neuzillet, Cindy, de Gramont, Armand, Tijeras-Raballand, Annemilaï, de Mestier, Louis, Cros, Jérome, Faivre, Sandrine, Raymond, Eric

“…Advanced pancreatic ductal adenocarcinoma (PDAC) and hepatocellular carcinoma (HCC) are non-curable diseases with a particularly poor prognosis. Over the last…”
Get full text

OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis by Astorgues-Xerri, Lucile, Riveiro, Maria E, Tijeras-Raballand, Annemilaï, Serova, Maria, Rabinovich, Gabriel A, Bieche, Ivan, Vidaud, Michel, de Gramont, Armand, Martinet, Mathieu, Cvitkovic, Esteban, Faivre, Sandrine, Raymond, Eric

“…Abstract Background Galectin-1 (Gal1), a carbohydrate-binding protein is implicated in cancer cell proliferation, invasion and tumour angiogenesis. Several…”
Get full text

Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients by Serova, Maria, Tijeras-Raballand, Annemilaï, Dos Santos, Célia, Albuquerque, Miguel, Paradis, Valerie, Neuzillet, Cindy, Benhadji, Karim A, Raymond, Eric, Faivre, Sandrine, de Gramont, Armand

“…Galunisertib (LY2157299) is a selective ATP-mimetic inhibitor of TGF-β receptor (TβR)-I activation currently under clinical investigation in hepatocellular…”
Get full text