Search Results - "Tigu, Adrian Bogdan"

The Role of Epigenetic Modifier Mutations in Peripheral T-Cell Lymphomas by Tigu, Adrian-Bogdan, Bancos, Anamaria

“…Peripheral T-cell lymphomas (PTCLs) are a group of diseases with a low incidence, high degree of heterogeneity, and a dismal prognosis in most cases. Because…”
Get full text

Transforming growth factor β‐mediated micromechanics modulates disease progression in primary myelofibrosis by Teodorescu, Patric, Pasca, Sergiu, Jurj, Ancuta, Gafencu, Grigore, Joelsson, Jon‐Petur, Selicean, Sonia, Moldovan, Cristian, Munteanu, Raluca, Onaciu, Anca, Tigu, Adrian‐Bogdan, Buse, Mihail, Zimta, Alina‐Andreea, Stiufiuc, Rares, Petrushev, Bobe, Desmirean, Minodora, Dima, Delia, Vlad, Cristina, Bergthorsson, Jon Thor, Berce, Cristian, Ciurea, Stefan, Ghiaur, Gabriel, Tomuleasa, Ciprian

“…Primary myelofibrosis (PMF) is a Ph‐negative myeloproliferative neoplasm (MPN), characterized by advanced bone marrow fibrosis and extramedullary…”
Get full text

Zeaxanthin-Rich Extract from Superfood Lycium barbarum Selectively Modulates the Cellular Adhesion and MAPK Signaling in Melanoma versus Normal Skin Cells In Vitro by Cenariu, Diana, Fischer-Fodor, Eva, Țigu, Adrian Bogdan, Bunea, Andrea, Virág, Piroska, Perde-Schrepler, Maria, Toma, Vlad-Alexandru, Mocan, Andrei, Berindan-Neagoe, Ioana, Pintea, Adela, Crișan, Gianina, Cenariu, Mihai, Maniu, Alma

“…The concern for implementing bioactive nutraceuticals in antioxidant-related therapies is of great importance for skin homeostasis in benign or malignant…”
Get full text

Nanoscale Investigation of DNA Demethylation in Leukemia Cells by Means of Ultrasensitive Vibrational Spectroscopy by Onaciu, Anca, Toma, Valentin, Moldovan, Cristian, Țigu, Adrian Bogdan, Cenariu, Diana, Culic, Carina, Borșa, Rareș Mario, David, Luca, Știufiuc, Gabriela Fabiola, Tetean, Romulus, Tomuleasa, Ciprian, Știufiuc, Rareș Ionuț

“…DNA methylation is a crucial epigenetic hallmark of cancer development but the experimental methods able to prove nanoscale modifications are very scarce. Over…”
Get full text

Exploring Periodontal Conditions, Salivary Markers, and Systemic Inflammation in Patients with Cardiovascular Diseases by Caloian, Carmen Silvia, Șurlin, Petra, Ciurea, Andreea, Pop, Dana, Caloian, Bogdan, Leucuța, Daniel Corneliu, Țigu, Adrian Bogdan, Rasperini, Giulio, Micu, Iulia Cristina, Stanomir, Alina, Soancă, Andrada, Roman, Alexandra

“…(1) Background: This cross-sectional investigation appreciated the role of serum C-reactive protein (CRP), several hematologic-cell markers, and salivary…”
Get full text

Insights into the Relationship between Periodontitis and Systemic Sclerosis Based on the New Periodontitis Classification (2018): A Cross-Sectional Study by Ciurea, Andreea, Stanomir, Alina, Șurlin, Petra, Micu, Iulia Cristina, Pamfil, Cristina, Leucuța, Daniel Corneliu, Rednic, Simona, Rasperini, Giulio, Soancă, Andrada, Țigu, Adrian Bogdan, Roman, Alexandra, Picoș, Andrei, Delean, Ada Gabriela

“…(1) Background: This study aimed to assess the periodontitis burden in systemic sclerosis patients and the possible association between them, and the degree to…”
Get full text

B Cells versus T Cells in the Tumor Microenvironment of Malignant Lymphomas. Are the Lymphocytes Playing the Roles of Muhammad Ali versus George Foreman in Zaire 1974? by Desmirean, Minodora, Rauch, Sebastian, Jurj, Ancuta, Pasca, Sergiu, Iluta, Sabina, Teodorescu, Patric, Berce, Cristian, Zimta, Alina-Andreea, Turcas, Cristina, Tigu, Adrian-Bogdan, Moldovan, Cristian, Paris, Irene, Steinheber, Jakob, Richlitzki, Cedric, Constantinescu, Catalin, Sigurjonsson, Olafur Eysteinn, Dima, Delia, Petrushev, Bobe, Tomuleasa, Ciprian

“…Malignant lymphomas are a heterogeneous group of malignancies that develop both in nodal and extranodal sites. The different tissues involved and the highly…”
Get full text

Editorial: Molecular targets in oncological and hematological disease management: innovations in precision medicine by Tigu, Adrian Bogdan, Wiedman, Gregory, Szedlacsek, Stefan Eugen

Get full text

An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes by Zimta, Alina-Andreea, Tigu, Adrian Bogdan, Braicu, Cornelia, Stefan, Cristina, Ionescu, Calin, Berindan-Neagoe, Ioana

“…The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which are reported in many studies as being overexpressed in various cancers…”
Get full text

Molecular Links between Central Obesity and Breast Cancer by Zimta, Alina-Andreea, Tigu, Adrian Bogdan, Muntean, Maximilian, Cenariu, Diana, Slaby, Ondrej, Berindan-Neagoe, Ioana

“…Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to incidence and mortality. In recent years, the negative role of obesity…”
Get full text

Exploring Novel Frontiers in Cancer Therapy by Tigu, Adrian Bogdan, Tomuleasa, Ciprian

“…Cancer progression and initiation are sustained by a series of alterations in molecular pathways because of genetic errors, external stimuli and other factors,…”
Get full text

The Synergistic Antitumor Effect of 5-Fluorouracil Combined with Allicin against Lung and Colorectal Carcinoma Cells by Țigu, Adrian Bogdan, Toma, Vlad-Alexandru, Moț, Augustin Cătălin, Jurj, Ancuța, Moldovan, Cristian Silviu, Fischer-Fodor, Eva, Berindan-Neagoe, Ioana, Pârvu, Marcel

“…5-fluorouracil (5-FU) is an anticancer drug used to inhibit the proliferation of many different tumor cells. Since severe events are associated with this…”
Get full text

Inhibitory Effect of CAPE and Kaempferol in Colon Cancer Cell Lines-Possible Implications in New Therapeutic Strategies by Budisan, Liviuta, Gulei, Diana, Jurj, Ancuta, Braicu, Cornelia, Zanoaga, Oana, Cojocneanu, Roxana, Pop, Laura, Raduly, Lajos, Barbat, Alexandru, Moldovan, Alin, Moldovan, Cristian, Tigu, Adrian Bogdan, Ionescu, Calin, Atanasov, Atanas G, Irimie, Alexandru, Berindan-Neagoe, Ioana

“…Phytochemicals are natural compounds synthesized as secondary metabolites in plants and represent an important source of molecules with therapeutic…”
Get full text

Phytochemical Analysis and In Vitro Effects of Allium fistulosum L. and Allium sativum L. Extracts on Human Normal and Tumor Cell Lines: A Comparative Study by Țigu, Adrian Bogdan, Moldovan, Cristian Silviu, Toma, Vlad-Alexandru, Farcaș, Anca Daniela, Moț, Augustin Cătălin, Jurj, Ancuța, Fischer-Fodor, Eva, Mircea, Cristina, Pârvu, Marcel

“…L. (garlic bulbs) and L. (Welsh onion leaves) showed quantitative differences of identified compounds: allicin and alliin (380 µg/mL and 1410 µg/mL in garlic;…”
Get full text

Design and preclinical testing of an anti‐CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia by Tigu, Adrian Bogdan, Constantinescu, Catalin Sorin, Teodorescu, Patric, Kegyes, David, Munteanu, Raluca, Feder, Richard, Peters, Mareike, Pralea, Ioana, Iuga, Cristina, Cenariu, Diana, Marcu, Andra, Tanase, Alina, Colita, Anca, Drula, Rares, Bergthorsson, Jon Thor, Greiff, Victor, Dima, Delia, Selicean, Cristina, Rus, Ioana, Zdrenghea, Mihnea, Gulei, Diana, Ghiaur, Gabriel, Tomuleasa, Ciprian

“…Abstract Acute megakaryoblastic leukaemia (AMkL) is a rare subtype of acute myeloid leukaemia (AML) representing 5% of all reported cases, and frequently…”
Get full text

RNA sequencing suggests that non‐coding RNAs play a role in the development of acquired haemophilia by Tigu, Adrian Bogdan, Hotea, Ionut, Drula, Rares, Zimta, Alina‐Andreea, Dirzu, Noemi, Santa, Maria, Constantinescu, Catalin, Dima, Delia, Bergthorsson, Jon Thor, Greiff, Victor, Gulei, Diana, Coriu, Daniel, Serban, Margit, Mahlangu, Johnny, Tomuleasa, Ciprian

“…Acquired haemophilia (AH) is a rare disorder characterized by bleeding in patients with no personal or family history of coagulation/clotting‐related diseases…”
Get full text

Agastache Species (Lamiaceae) as a Valuable Source of Volatile Compounds: GC-MS Profiling and Investigation of In Vitro Antibacterial and Cytotoxic Activities by Nechita, Mihaela-Ancuța, Pralea, Ioana-Ecaterina, Țigu, Adrian-Bogdan, Iuga, Cristina-Adela, Pop, Carmen Rodica, Gál, Emese, Vârban, Rodica, Nechita, Vlad-Ionuț, Oniga, Ovidiu, Toiu, Anca, Benedec, Daniela, Hanganu, Daniela, Oniga, Ilioara

“…Nowadays, there is an increasing interest in the study of medicinal and aromatic plants, due to their therapeutic properties that correlate with the presence…”
Get full text

In vivo imaging system (IVIS) therapeutic assessment of tyrosine kinase inhibitor-loaded gold nanocarriers for acute myeloid leukemia: a pilot study by Munteanu, Raluca-Andrada, Tigu, Adrian Bogdan, Feder, Richard, Tatar, Andra-Sorina, Gulei, Diana, Tomuleasa, Ciprian, Boca, Sanda

“…Acute myeloid leukemia (AML) is a malignancy in the myeloid lineage that is characterized by symptoms like fatigue, bleeding, infections, or anemia, and it can…”
Get full text

Epigenetic and Molecular Alterations in Obesity: Linking CRP and DNA Methylation to Systemic Inflammation by Cucoreanu, Ciprian, Tigu, Adrian-Bogdan, Nistor, Madalina, Moldovan, Radu-Cristian, Pralea, Ioana-Ecaterina, Iacobescu, Maria, Iuga, Cristina-Adela, Szabo, Robert, Dindelegan, George-Calin, Ciuce, Constatin

“…Obesity is marked by excessive fat accumulation in the adipose tissue, which disrupts metabolic processes and causes chronic systemic inflammation. Commonly,…”
Get full text

The Effect of Different Anesthetic Techniques on Proliferation, Apoptosis, and Gene Expression in Colon Cancer Cells: A Pilot In Vitro Study by Alexa, Alexandru Leonard, Jurj, Ancuta, Tomuleasa, Ciprian, Tigu, Adrian Bogdan, Hategan, Raluca-Miorita, Ionescu, Daniela

“…Colorectal cancer is highly common and causes high mortality rates. Treatment for colorectal cancer is multidisciplinary, but in most cases the main option…”
Get full text