Search Results - "Tigley, AW"

TNF-alpha contributes to the pathogenesis of ethanol-induced gastric damage in cirrhotic rats by Ferraz, J G, Tigley, A W, Appleyard, C B, Wallace, J L

“…Cirrhotic rats exhibit increased susceptibility to ethanol-induced gastric damage, but the underlying mechanism for this phenomenon remains unclear…”
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Induction of cyclooxygenase 1 and 2 in the rat stomach during endotoxemia: Role in resistance to damage by Ferraz, JG, Sharkey, KA, Reuter, BK, Asfaha, S, Tigley, AW, Brown, ML, McKnight, W, Wallace, JL

“…BACKGROUND & AIMS: Prostaglandins and nitric oxide are key mediators of gastric mucosal defense. Endotoxemia alters gastric resistance to damage, but little is…”
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Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence by Appleyard, C B, McCafferty, D M, Tigley, A W, Swain, M G, Wallace, J L

“…Neutrophil adherence to the vascular endothelium has been suggested to be a critical event in the pathogenesis of nonsteroidal anti-inflammatory drug…”
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The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase by Howlett, C J, Bisson, S A, Resek, M E, Tigley, A W, Robbins, S M

“…Hematopoietic cell kinase (Hck) is a member of the Src-family of protein tyrosine kinases. We have found that upon enzymatic activation of Hck by the heavy…”
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