Search Results - "Tighe, Scott"
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Advanced biofilm analysis in streams receiving organic deicer runoff
Published in PloS one (22-01-2020)“…Prolific heterotrophic biofilm growth is a common occurrence in airport receiving streams containing deicers and anti-icers, which are composed of…”
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Real-Time DNA Sequencing in the Antarctic Dry Valleys Using the Oxford Nanopore Sequencer
Published in Journal of biomolecular techniques (01-04-2017)“…The ability to sequence DNA outside of the laboratory setting has enabled novel research questions to be addressed in the field in diverse areas, ranging from…”
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3
Comprehensive benchmarking and ensemble approaches for metagenomic classifiers
Published in Genome Biology (21-09-2017)“…One of the main challenges in metagenomics is the identification of microorganisms in clinical and environmental samples. While an extensive and heterogeneous…”
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Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study
Published in Nature biotechnology (01-09-2021)“…Assessing the reproducibility, accuracy and utility of massively parallel DNA sequencing platforms remains an ongoing challenge. Here the Association of…”
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Factors influencing recovery of SARS-CoV-2 RNA in raw sewage and wastewater sludge using polyethylene glycol-based concentration method
Published in Journal of biomolecular techniques (01-09-2021)“…Wastewater surveillance for monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important epidemiologic tool for the assessment of…”
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Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step
Published in PLoS biology (02-10-2020)“…The ongoing COVID-19 pandemic has created an unprecedented need for rapid diagnostic testing. The World Health Organization (WHO) recommends a standard assay…”
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Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study
Published in Nature biotechnology (01-09-2014)“…For intact RNA, gene expression profiles from rRNA-depletion and poly-A enrichment are similar. In addition, rRNA- depletion enables effective analysis of…”
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Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model
Published in Nature communications (24-05-2021)“…About 20–25% of dengue virus (DENV) infections become symptomatic ranging from self-limiting fever to shock. Immune gene expression changes during progression…”
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Characterizing species interactions that contribute to biofilm formation in a multispecies model of a potable water bacterial community
Published in Microbiology (Society for General Microbiology) (01-01-2020)“…Microbial biofilms are ubiquitous in drinking water systems, yet our understanding of drinking water biofilms lags behind our understanding of those in other…”
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Genomic and morphological characterization of Knufia obscura isolated from the Mars 2020 spacecraft assembly facility
Published in Scientific reports (28-05-2024)“…Members of the family Trichomeriaceae, belonging to the Chaetothyriales order and the Ascomycota phylum, are known for their capability to inhabit hostile…”
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Metagenomic analysis of Aedes aegypti and Culex quinquefasciatus mosquitoes from Grenada, West Indies
Published in PloS one (13-04-2020)“…The mosquitoes Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) and Culex quinquefasciatus Say, 1823 (Diptera: Culicidae) are two major vectors of…”
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Acetate Supplementation as a Means of Inducing Glioblastoma Stem-Like Cell Growth Arrest
Published in Journal of cellular physiology (01-08-2015)“…Glioblastoma (GBM), the most common primary adult malignant brain tumor, is associated with a poor prognosis due, in part, to tumor recurrence mediated by…”
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Author Correction: Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study
Published in Nature biotechnology (01-11-2021)Get full text
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14
Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
Published in Journal of biomolecular techniques (01-09-2021)“…As the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of…”
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Acetate supplementation induces growth arrest of NG2/PDGFRα-positive oligodendroglioma-derived tumor-initiating cells
Published in PloS one (20-11-2013)“…Cancer is associated with globally hypoacetylated chromatin and considerable attention has recently been focused on epigenetic therapies. N-acetyl-L-aspartate…”
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Life and its traces in Antarctica's McMurdo Dry Valley paleolakes: a survey of preservation
Published in Micron (Oxford, England : 1993) (01-04-2020)“…•Scanning electron microscopy reveals possible nanobacteria in the McMurdo Dry Valley.•Moss long extinct from the region imaged via light and scanning electron…”
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High prevalence of Phasi Charoen-like virus from wild-caught Aedes aegypti in Grenada, W.I. as revealed by metagenomic analysis
Published in PloS one (31-01-2020)“…Arboviruses cause diseases of significant global health concerns. Interactions between mosquitoes and their microbiota as well as the important role of this…”
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Validating an Automated Nucleic Acid Extraction Device for Omics in Space Using Whole Cell Microbial Reference Standards
Published in Frontiers in microbiology (21-08-2020)“…NASA has made great strides in the past five years to develop a suite of instruments for the International Space Station in order to perform molecular biology…”
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Molecular Characterization of Increased Amplicon Lengths in SARS-CoV-2 Reverse Transcription Loop-Mediated Isothermal Amplification Assays
Published in Journal of biomolecular techniques (01-09-2021)“…Loop-mediated isothermal amplification (LAMP) is a power tool for the amplification of specific RNA and DNA targets. Much like PCR, LAMP requires primers that…”
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Microbiome and metagenomic analysis of Lake Hillier Australia reveals pigment-rich polyextremophiles and wide-ranging metabolic adaptations
Published in Environmental microbiome (21-12-2022)“…Lake Hillier is a hypersaline lake known for its distinctive bright pink color. The cause of this phenomenon in other hypersaline sites has been attributed to…”
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