Search Results - "Tighanimine, Khaled"
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Promitotic Action of Oenothera biennis on Senescent Human Dermal Fibroblasts
Published in International journal of molecular sciences (02-12-2022)“…Accumulation of senescent dermal fibroblasts drives skin aging. The reactivation of proliferation is one strategy to modulate cell senescence. Recently, we…”
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Lipid remodeling in context of cellular senescence
Published in Biochimie (17-09-2024)“…Cellular senescence is a response that irreversibly arrests stressed cells thus providing a potent tumor suppressor mechanism. In parallel, senescent cells…”
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Accumulation of G3P and pEtN drives cellular senescence via altered lipid metabolism
Published in Nature metabolism (01-02-2024)“…Glycerol-3-Phosphate (G3P) and phosphoethanolamine (pEtN) biosynthetic pathways are modulated during senescence establishment to sustain lipid droplet…”
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A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism
Published in Nature metabolism (01-02-2024)“…Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory…”
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