Search Results - "Tiganescu, Ana"

Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases-A Focus on Psoriasis and Lupus erythematosus by Berekméri, Anna, Tiganescu, Ana, Alase, Adewonuola A, Vital, Edward, Stacey, Martin, Wittmann, Miriam

“…The traditional diagnostic gold standard for inflammatory skin lesions of unclear etiology is dermato-histopathology. As this approach requires an invasive…”
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Increased glucocorticoid activation during mouse skin wound healing by Tiganescu, Ana, Hupe, Melanie, Uchida, Yoshikazu, Mauro, Theodora, Elias, Peter M, Holleran, Walter M

“…Glucocorticoid (GC) excess inhibits wound healing causing increased patient discomfort and infection risk. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)…”
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Automated quantification of 3D wound morphology by machine learning and optical coherence tomography in type 2 diabetes by Wang, Yinhai, Freeman, Adrian, Ajjan, Ramzi, Galdo, Francesco, Tiganescu, Ana

“…Background Driven by increased prevalence of type 2 diabetes and ageing populations, wounds affect millions of people each year, but monitoring and treatment…”
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11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects by Tiganescu, Ana, Tahrani, Abd A, Morgan, Stuart A, Otranto, Marcela, Desmouliere, Alexis, Abrahams, Lianne, Hassan-Smith, Zaki, Walker, Elizabeth A, Rabbitt, Elizabeth H, Cooper, Mark S, Kurt, Amrein, Lavery, Gareth G, Stewart, Paul M

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The Effect of Endogenous Cushing Syndrome on All-cause and Cause-specific Mortality by Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Baxter, Paul D, Nyawira Nyaga, Victoria, Pujades-Rodriguez, Mar, Stewart, Paul M

“…We aimed to perform a systematic review and meta-analysis of all-cause and cause-specific mortality of patients with benign endogenous Cushing syndrome (CS)…”
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The Prediction and Monitoring of Toxicity Associated with Long-Term Systemic Glucocorticoid Therapy by Harris, Emma, Tiganescu, Ana, Tubeuf, Sandy, Mackie, Sarah Louise

“…Glucocorticoids are often required for adequate control of inflammation in many serious inflammatory diseases; common indications for long-term treatment…”
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Inhibition of the glucocorticoid‐activating enzyme 11β‐hydroxysteroid dehydrogenase type 1 drives concurrent 11‐oxygenated androgen excess by Schiffer, Lina, Oestlund, Imken, Snoep, Jacky L., Gilligan, Lorna C., Taylor, Angela E., Sinclair, Alexandra J., Singhal, Rishi, Freeman, Adrian, Ajjan, Ramzi, Tiganescu, Ana, Arlt, Wiebke, Storbeck, Karl‐Heinz

“…Aldo‐keto reductase 1C3 (AKR1C3) is a key enzyme in the activation of both classic and 11‐oxygenated androgens. In adipose tissue, AKR1C3 is co‐expressed with…”
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Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin by Tiganescu, Ana, Walker, Elizabeth A., Hardy, Rowan S., Mayes, Andrew E., Stewart, Paul M.

“…Glucocorticoids (GCs) are highly detrimental to skin integrity and function both when applied topically for anti-inflammatory treatments and during conditions…”
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Topical 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Corrects Cutaneous Features of Systemic Glucocorticoid Excess in Female Mice by Tiganescu, Ana, Hupe, Melanie, Uchida, Yoshikazu, Mauro, Theadora, Elias, Peter M, Holleran, Walter M

“…Abstract Glucocorticoid (GC) excess drives multiple cutaneous adverse effects, including skin thinning and poor wound healing. The ubiquitously expressed…”
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11 beta -Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects by Tiganescu, Ana, Tahrani, Abd A, Morgan, Stuart A, Otranto, Marcela, Desmouliere, Alexis, Abrahams, Lianne, Hassan-Smith, Zaki, Walker, Elizabeth A, Rabbitt, Elizabeth H, Cooper, Mark S, Amrein, Kurt, Lavery, Gareth G, Stewart, Paul M

“…Glucocorticoid (GC) excess adversely affects skin integrity, inducing thinning and impaired wound healing. Aged skin, particularly that which has been…”
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LEGAL ASPECTS OF THE CONTRACT OF PUBLIC-PRIVATE PARTNERSHIP by Tiganescu, Ana-Maria

“…Due to the legislative instability in this field, the contract of publicprivate partnership benefits from a relatively new regulation in the matter. This paper…”
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MON-157 The Effect of Exogenous Cushing’s Syndrome on All-Cause and Cause-Specific Mortality: A Systematic Review by Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Stewart, Paul Michael, Pujades-Rodriguez, Mar D M

“…Abstract Chronic oral glucocorticoid (GC) exposure from therapeutic anti-inflammatory or immunosuppressive use is the most common cause of Cushing’s syndrome…”
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Mortality and Specific Causes of Death in Endogenous Cushing’s Syndrome: A Systematic Review, Meta-Analysis and Meta-Regression by Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Pujades-Rodriguez, Mar, Nyaga, Victoria Nyawira, Baxter, Paul D, Stewart, Paul Michael

“…Abstract Background: Endogenous Cushing’s syndrome (CS) refers to an inappropriate hypercortisolism usually caused by either Cushing’s disease (CD) or adrenal…”
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Real World Mortality and Specific Causes of Death in Chronic Oral Glucocorticoid Use: A Systematic Review, Meta-Analysis and Meta-Regression by Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Nyaga, Victoria N, Rodriguez, Mar Pujades, Baxter, Paul D, Stewart, Paul Michael

“…Abstract Background: Glucocorticoids (GCs) are widely used as therapeutic agents with prevalence 0.9–3.7%, but they are associated with significant side…”
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Aspects referring to the international cooperation on the protection of the Black Sea against pollution by Tiganescu, Ana-Maria

“…The pollution of the seas in general (implicitly of the Black Sea) is a universal problem affecting all countries, both developed and developing ones, all in…”
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Legal aspects regarding waters administration, use and management in Romania by Tiganescu, Ana-Maria

“…The main "enemies" of water are the lack or insufficiency of works necessary for the rational use of the entire water stock, and the pollution. In such a…”
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UVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo by Tiganescu, Ana, Hupe, Melanie, Jiang, Yan J., Celli, Anna, Uchida, Yoshikazu, Mauro, Theodora M., Bikle, Daniel D., Elias, Peter M., Holleran, Walter M.

“…Detrimental consequences of ultraviolet radiation (UVR) in skin include photoageing, immunosuppression and photocarcinogenesis, processes also significantly…”
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Basin-scale distribution patterns of photosynthetic picoeukaryotes along an Atlantic Meridional Transect by Kirkham, Amy R., Jardillier, Ludwig E., Tiganescu, Ana, Pearman, John, Zubkov, Mikhail V., Scanlan, David J.

“…Summary Photosynthetic picoeukaryotes (PPEs) of a size < 3 µm play a crucial role in oceanic primary production. However, little is known of the structure of…”
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Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency by Lavery, Gareth G., Walker, Elizabeth A., Tiganescu, Ana, Ride, Jon P., Shackleton, Cedric H. L., Tomlinson, Jeremy W., Connell, John M. C., Ray, David W., Biason-Lauber, Anna, Malunowicz, Ewa M., Arlt, Wiebke, Stewart, Paul M.

“…Context: Cortisone reductase deficiency (CRD) is characterized by a failure to regenerate cortisol from cortisone via 11β-hydroxysteroid dehydrogenase type 1…”
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SUPPUVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo by Tiganescu, Ana, Hupe, Melanie, Jiang, Yan J., Celli, Anna, Uchida, Yoshikazu, Mauro, Theodora M., Bikle, Daniel D., Elias, Peter M., Holleran, Walter M.

“…Detrimental consequences of ultraviolet radiation (UVR) in skin include photoageing, immunosuppression and photocarcinogenesis, processes also significantly…”
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