Search Results - "Tiftik,Rukiye Nalan"
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mTORC2 inhibition by JR-AB2-011 improves IL-1β-induced inflammation, catabolic response, and apoptosis in human chondrocytes through IκB-α/NF-κB p65
Published in Cellular and Molecular Biology (08-10-2024)“…Osteoarthritis (OA) is a very common chronic joint condition marked by inflammation and cartilage loss. mTOR is a well-known mediator of inflammation, cell…”
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Involvement of Rho-kinase/IκB-α/NF-κB activation in IL-1β-induced inflammatory response and oxidative stress in human chondrocytes
Published in Canadian journal of physiology and pharmacology (01-04-2021)“…It has been clearly indicated that osteoarthritis (OA) is an inflammatory and degenerative disease that could be promoted by Rho-kinase (ROCK); however, little…”
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Comparative investigation of antitumoral effectiveness of Rho-kinase inhibitor Y-27632, pravastatin and atorvastatin in anaplastic thyroid cancer cell culture
Published in Journal of oncological science (01-07-2017)“…Anaplastic thyroid cancer is an aggressive malignancy with a poor prognosis. In metastatic cases instead of treatment alternatives including surgery,…”
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Contribution of Rho-kinase in human gallbladder contractions
Published in European journal of pharmacology (01-07-2006)“…Rho/Rho-kinase-mediated pathway has been involved in a variety of physiological processes, including Ca 2+ sensitization, which enhances smooth muscle…”
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Effects of 17β-estradiol and progesterone on the production of adipokines in differentiating 3T3-L1 adipocytes: Role of Rho-kinase
Published in Cytokine (Philadelphia, Pa.) (01-04-2015)“…•17β-estradiol elevated resistin but decreased adiponectin and IL-6 levels.•Y-27632 inhibited the rise of resistin and fall of adiponectin by…”
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Association of Angiotensin‐Converting Enzyme Gene Insertion/Deletion Polymorphism with Allergic Contact Dermatitis
Published in Basic & clinical pharmacology & toxicology (01-08-2007)“…: Angiotensin‐converting enzyme (ACE) plays an important role in the physiological control of blood pressure and inflammation. Insertion/deletion (I/D)…”
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Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli
Published in European journal of pharmacology (28-12-2005)“…Rho kinase has contractile activity, which induces Ca 2+ sensitization in various cells. Several receptors are linked to the Rho/Rho-kinase pathway. Therefore,…”
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Rho-kinase (ROCK-1 and ROCK-2) upregulation in oleic acid-induced lung injury and its restoration by Y-27632
Published in European journal of pharmacology (07-03-2005)“…The possible contribution of Rho/Rho-kinase signalling in oleic acid (100 mg kg −1, i.v., for 4 h)-induced lung injury was investigated in rats. Furthermore,…”
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Non-prescription drug use in a group of medical students: For success
Published in Inönü Üniversitesi Turgut Özal Tıp Merkezi dergisi (01-04-2019)“…Aim: Non-prescription drug use is a common problem in the population and also among medical students. Medical education requires great efforts and students may…”
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