Search Results - "Tietze, Rainer"
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Magnetic nanoparticle-based drug delivery for cancer therapy
Published in Biochemical and biophysical research communications (18-12-2015)“…Nanoparticles have belonged to various fields of biomedical research for quite some time. A promising site-directed application in the field of nanomedicine is…”
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Functionalized Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as Platform for the Targeted Multimodal Tumor Therapy
Published in Frontiers in oncology (13-02-2019)“…Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and immunotherapy. In clinical practice, the respective drugs are applied orally or…”
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Critical Offset Magnetic PArticle SpectroScopy for rapid and highly sensitive medical point-of-care diagnostics
Published in Nature communications (24-11-2022)“…Magnetic nanoparticles (MNPs) have been adapted for many applications, e.g., bioassays for the detection of biomarkers such as antibodies, by controlled…”
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Nanoparticles for radiooncology: Mission, vision, challenges
Published in Biomaterials (01-03-2017)“…Abstract Cancer is one of the leading non-communicable diseases with highest mortality rates worldwide. About half of all cancer patients receive radiation…”
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SPION based nanoformulations: bio-inspired design and functionalization strategies for applications in medicine
Published in Precision nanomedicine (12-05-2022)“…<img src=” https://s3.amazonaws.com/production.scholastica/article/35650/large/photo-1597423498323-e7e7554b83c6?1652369616”> Biomedical applications in…”
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Efficient drug-delivery using magnetic nanoparticles — biodistribution and therapeutic effects in tumour bearing rabbits
Published in Nanomedicine (01-10-2013)“…Abstract To treat tumours efficiently and spare normal tissues, targeted drug delivery is a promising alternative to conventional, systemic administered…”
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Synthesis and Characterization of Citrate-Stabilized Gold-Coated Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications
Published in Molecules (Basel, Switzerland) (26-09-2020)“…Surface-functionalized gold-coated superparamagnetic iron oxide nanoparticles (Au-SPIONs) may be a useful tool in various biomedical applications. To obtain…”
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Plasmid-DNA Delivery by Covalently Functionalized PEI-SPIONs as a Potential ‘Magnetofection’ Agent
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Nanoformulations for delivering nucleotides into cells as vaccinations as well as treatment of various diseases have recently gained great attention. Applying…”
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Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release
Published in International journal of molecular sciences (16-04-2021)“…Hydroxyapatite- or calcium phosphate-coated iron oxide nanoparticles have a high potential for use in many biomedical applications. In this study, a…”
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Biomimetic Magnetic Particles for the Removal of Gram-Positive Bacteria and Lipoteichoic Acid
Published in Pharmaceutics (31-10-2022)“…Gram+ bacteria are very common in clinical medicine and responsible for a large number of infectious diseases. For example, Gram+ bacteria play a major role in…”
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Synthesis and Characterization of Tissue Plasminogen Activator-Functionalized Superparamagnetic Iron Oxide Nanoparticles for Targeted Fibrin Clot Dissolution
Published in International journal of molecular sciences (24-08-2017)“…Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted great attention in many biomedical fields and are used in preclinical/experimental drug…”
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Magnetic nanoparticles for cancer therapy
Published in Nanotechnology reviews (Berlin) (01-08-2013)“…Cancer is one of the biggest challenges facing the medical research in our time. The goals are to improve not only the therapeutic outcome, even in the cases…”
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Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes
Published in International journal of molecular sciences (02-04-2013)“…Magnetic drug targeting (MDT) improves the integrity of healthy tissues and cells during treatment with cytotoxic drugs. An anticancer drug is bound to…”
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Effect of Citrate- and Gold-Stabilized Superparamagnetic Iron Oxide Nanoparticles on Head and Neck Tumor Cell Lines during Combination Therapy with Ionizing Radiation
Published in Bioengineering (Basel) (01-12-2022)“…Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. They are associated with alcohol and tobacco consumption, as well as…”
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In Vitro Analysis of Superparamagnetic Iron Oxide Nanoparticles Coated with APTES as Possible Radiosensitizers for HNSCC Cells
Published in Nanomaterials (Basel, Switzerland) (12-01-2023)“…Superparamagnetic iron oxide nanoparticles (SPION) are being investigated for many purposes, e.g., for the amplification of ionizing radiation and for the…”
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Tangential Flow Ultrafiltration Allows Purification and Concentration of Lauric Acid-/Albumin-Coated Particles for Improved Magnetic Treatment
Published in International journal of molecular sciences (14-08-2015)“…Superparamagnetic iron oxide nanoparticles (SPIONs) are frequently used for drug targeting, hyperthermia and other biomedical purposes. Recently, we have…”
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Boron containing magnetic nanoparticles for neutron capture therapy – an innovative approach for specifically targeting tumors
Published in Applied radiation and isotopes (01-12-2015)“…The selective delivery of 10B into the tumor tissue remains to be further improved for successful and reliable Boron Neutron Capture Therapy applications…”
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Synthesis, Radiofluorination, and In Vitro Evaluation of Pyrazolo[1,5-a]pyridine-Based Dopamine D4 Receptor Ligands: Discovery of an Inverse Agonist Radioligand for PET
Published in Journal of medicinal chemistry (27-03-2008)“…A series of fluoro-substituted analogs structurally derived from the aminomethyl-substituted pyrazolo[1,5-a]pyridine lead compounds 9 (FAUC 113) and 10 (FAUC…”
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Improving cancer imaging with magnetic nanoparticles: where are we now?
Published in Nanomedicine (London, England) (01-02-2017)“…Husband and Rezneck have noted principles for choosing the right imaging technique, that seems to be still a helpful orientation (2). [...]each methodology has…”
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Imaging modalities using magnetic nanoparticles – overview of the developments in recent years
Published in Nanotechnology reviews (Berlin) (01-08-2013)“…The use of nanoparticles in tumor imaging, molecular imaging, and drug delivery has significantly expanded in the last few years. The relatively new field of…”
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