Search Results - "Tietz, P"

Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion by Tietz, P, Jefferson, J, Pagano, R, LaRusso, N. F

“…The formation of hepatic bile requires that water be transported across liver epithelia. Rat hepatocytes express three aquaporins (AQPs): AQP8, AQP9, and AQP0…”
Get full text

Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes by Tietz, P S, Alpini, G, Pham, L D, Larusso, N F

“…Previous work from our laboratory has implicated hormone-induced plasma membrane movement (i.e., endo- and exocytosis) in water and electrolyte transport by…”
Get full text

Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes by Marinelli, R A, Tietz, P S, Pham, L D, Rueckert, L, Agre, P, LaRusso, N F

“…Aquaporin-1 (AQP1) water channels are present in the apical and basolateral plasma membrane domains of bile duct epithelial cells, or cholangiocytes, and…”
Get full text

Upregulation of secretin receptors on cholangiocytes after bile duct ligation by Tietz, P.S., Hadac, E.M., Miller, L.J., LaRusso, N.F.

“…Secretin not only increases ductular bile secretion in vivo in rats after bile duct ligation (BDL) [1], but also increases cAMP levels and stimulates…”
Get full text

Expression of aquaporin‐4 water channels in rat cholangiocytes by Marinelli, Raúl A., Pham, Linh D., Tietz, Pamela S., LaRusso, Nicholas F.

“…We recently reported that secretin induces the exocytic insertion of functional aquaporin‐1 water channels (AQP1) into the apical membrane of cholangiocytes…”
Get full text

Circadian rhythms of biliary protein and lipid excretion in rats by Nakano, A, Tietz, P S, LaRusso, N F

“…To gain insight into the mechanisms by which hepatocytes release lipids and proteins into bile, we studied extended, steady-state secretion of bile, lipids,…”
Get full text

Quantitative importance of biliary excretion to the turnover of hepatic lysosomal enzymes by Nakano, A, Marks, D L, Tietz, P S, de Groen, P C, LaRusso, N F

“…The turnover rate of an individual protein is a function of the rates of synthesis and loss of that protein. For most intracellular proteins, loss occurs…”
Get more information

Cholangiocyte-specific rat liver proteins identified by establishment of a two-dimensional gel protein database by Tietz, P, de Groen, P C, Anderson, N L, Sims, C, Esquer-Blasco, R, Meheus, L, Raymackers, J, Dauwe, M, LaRusso, N F

“…The liver is composed of a variety of cells that form a functional unit involved in uptake, synthesis, metabolism, and secretion. Until recently, most studies…”
Get more information

Isolation and characterization of rat cholangiocyte vesicles enriched in apical or basolateral plasma membrane domains by Tietz, Pamela S, Holman, Ralph T, Miller, Laurence J, LaRusso, Nicholas F

“…Cholangiocytes, the epithelial cells that line intrahepatic bile ducts, are composed of plasma membranes with discrete apical (lumenal) and basolateral…”
Get full text

A quasilinear transmission problem with application to Maxwell equations with a divergence-free D-field by Dohnal, Tomáš, Romani, Giulio, Tietz, Daniel P.

“…Maxwell equations in the absence of free charges require initial data with a divergence-free displacement field D. In materials in which the dependence D=D(E)…”
Get full text

Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes by MAZZONE, Amelia, TIETZ, Pamela, JEFFERSON, John, PAGANO, Richard, LARUSSO, Nicholas F

“…Canalicular bile is formed by the osmotic filtration of water in response to osmotic gradients generated by active transport at the apical and basolateral…”
Get full text

Dynamic measurements of the acute and chronic effects of lysosomotropic agents on hepatocyte lysosomal pH using flow cytometry by Myers, B M, Tietz, P S, Tarara, J E, LaRusso, N F

“…Previous investigators measuring the pH of lysosomes have used digitized video microscopy (DVM) in freshly isolated or cultured cells. Although useful, this…”
Get more information

Control design of Santo Tome back-to-back HVDC link by Rostamkolai, N., Wegner, C.A., Piwko, R.J., Elahi, H., Eitzmann, M.A., Garzi, G., Tietz, P.

“…The authors describe the control design of the Santo Tome back-to-back high voltage DC (HVDC) link. The Santo Tome HVDC converter will be the second DC link…”
Get full text

Development and validation of a method for measuring the glycine and taurine conjugates of bile acids in bile by high-performance liquid chromatography by Tietz, P S, Thistle, J L, Miller, L J, LaRusso, N F

“…We developed and validated a simple method for measuring the individual glycine and taurine conjugates of bile acids in bile by high-performance liquid…”
Get more information

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter by Lazaridis, K N, Pham, L, Tietz, P, Marinelli, R A, deGroen, P C, Levine, S, Dawson, P A, LaRusso, N F

“…Although bile acid transport by bile duct epithelial cells, or cholangiocytes, has been postulated, the details of this process remain unclear. Thus, we…”
Get full text

Purification and immunological quantification of rat liver lysosomal glycosidases by de Groen, P C, LeSage, G D, Tietz, P S, LaRusso, N F

“…Although lysosomal enzyme activities are known to vary in response to numerous physiological and pharmacological stimuli, the relationship between lysosomal…”
Get full text

Synthesis and biological activity of vitamin D3 3 beta-sulfate. Role of vitamin D3 sulfates in calcium homeostasis by Nagubandi, S, Londowski, J M, Bollman, S, Tietz, P, Kumar, R

“…To determine the biological activity of vitamin D sulfates, we synthesized vitamin D3 3 beta-sulfate and tested its biological activity in vitamin D-deficient…”
Get full text

Alternative Splicing of the Rat Sodium/Bile Acid Transporter Changes Its Cellular Localization and Transport Properties by Lazaridis, Konstantinos N., Tietz, Pam, Wu, Ting, Kip, Sertac, Dawson, Paul A., LaRusso, Nicholas F.

“…Bile secretion involves the structural and functional interplay of hepatocytes and cholangiocytes, the cells lining the intrahepatic bile ducts. Hepatocytes…”
Get full text

Time-dependent effects of chloroquine on pH of hepatocyte lysosomes by Tietz, P S, Yamazaki, K, LaRusso, N F

“…In vivo administration of chloroquine to rats caused an increase in the pH of hepatocyte lysosomes within 1 hr after administration with a return to baseline…”
Get more information

Role of vitamin D glucosiduronate in calcium homeostasis by Nagubandi, S, Kumar, R, Londowski, J M, Corradino, R A, Tietz, P S

“…Evidence has been presented suggesting the presence of vitamin D(3) 3beta-glucosiduronate and 1,25-dihydroxyvitamin D(3) glucosiduronate in rat bile. To…”
Get full text