Search Results - "Tiera, Marcio José"

Synthesis, Characterization, and Antifungal Activities of Amphiphilic Derivatives of Diethylaminoethyl Chitosan against Aspergillus flavus by Gabriel, Juliana dos Santos, Tiera, Marcio José, Tiera, Vera Aparecida de Oliveira

“…Amphiphilic derivatives of diethylaminoethyl chitosan (DEAE-CH) were synthesized using a two-step process involving initial substitution with diethylaminoethyl…”
Get full text

Impact of Degree of Ionization and PEGylation on the Stability of Nanoparticles of Chitosan Derivatives at Physiological Conditions by Martinez Junior, André Miguel, Lima, Aline Margarete Furuyama, Martins, Grazieli Olinda, Tiera, Vera Aparecida de Oliveira, Benderdour, Mohamed, Fernandes, Julio Cesar, Tiera, Marcio José

“…Nowadays, the therapeutic efficiency of small interfering RNAs (siRNA) is still limited by the efficiency of gene therapy vectors capable of carrying them…”
Get full text

Biopolymeric Films of Amphiphilic Derivatives of Chitosan: A Physicochemical Characterization and Antifungal Study by Alves, Anna Carolina Rodrigues Santos, Lima, Aline Margarete Furuyama, Tiera, Marcio José, Aparecida de Oliveira Tiera, Vera

“…The chemical modification of chitosan has been an active subject of research in order to improve the physicochemical and antifungal properties of…”
Get full text

Synthesis and self-assembly study of zwitterionic amphiphilic derivatives of chitosan by Franciane Gonçalves Barbosa, Hellen, Margarete Furuyama Lima, Aline, Roberto Taboga, Sebastião, Cesar Fernandes, Júlio, Aparecida de Oliveira Tiera, Vera, José Tiera, Marcio

“…ABSTRACT New zwitterionic derivatives of chitosan (CH) were synthesized through the Michael addition reaction of 1‐(3‐sulfopropyl)‐2‐vinylpyridine hydroxide…”
Get full text

Synthesis, characterization and antifungal activity of quaternary derivatives of chitosan on Aspergillus flavus by de Oliveira Pedro, Rafael, Takaki, Mirelle, Gorayeb, Teresa Cristina Castilho, Bianchi, Vanildo Luiz Del, Thomeo, João Cláudio, Tiera, Marcio José, de Oliveira Tiera, Vera Aparecida

“…Two series of new chitosan derivatives were synthesized by reaction of deacetylated chitosan (CH) with propyl (CH-Propyl) and pentyl (CH-Pentyl)…”
Get full text

Tuning with Phosphorylcholine Grafts Improves the Physicochemical Properties of PLL/pDNA Nanoparticles at Neutral pH by Semensato, Juliana, Fernandes, Júlio Cesar, Benderdour, Mohamed, de Oliveira Tiera, Vera Aparecida, Lima, Aline Margarete Furuyama, Tiera, Marcio José

“…The improvement of biological properties of polycations is a fundamental step to overcome their limitations as non-viral gene carriers. This work studied the…”
Get full text

A fluorescence probe study of gemini surfactants in aqueous solution: a comparison between n-2-n and n-6-n series of the alkanediyl-a,w-bis (dimethylalkylammonium bromides) by Da Silveira Júnior, Pedro Belchior, Tiera, Vera Aparecida de Oliveira, Tiera, Marcio José

“…Two series of alkanediyl-a,w-bis (dimethylalkylammonium bromide (n-2-n and n-6-n; n=8, 10,12,and 16) have been synthesized and their micelles properties…”
Get full text

Effect of Surfactants and Polyethylene Glycol on the Activity and Stability of a Lipase from Oilseeds of Pachira aquatica by Polizelli, Patricia Peres, Tiera, Márcio José, Bonilla-Rodriguez, Gustavo Orlando

“…Lipases from oilseeds have a great potential for commercial exploration as industrial enzymes. Lipases are used mixed with surfactants in cleaning and other…”
Get full text

Hydrophobic effect of amphiphilic derivatives of chitosan on the antifungal activity against Aspergillus flavus and Aspergillus parasiticus by Viegas de Souza, Ricchard Hallan Felix, Takaki, Mirelli, de Oliveira Pedro, Rafael, dos Santos Gabriel, Juliana, Tiera, Marcio José, de Oliveira Tiera, Vera Ap

“…Low molecular weight amphiphilic derivatives of chitosan were synthesized, characterized and their antifungal activities against Aspergillus flavus and…”
Get full text

Tuning the surface charge and colloidal stability of hybrid gold-chitosan derivative nanoparticles for siRNA delivery by Martinez Júnior, André Miguel, Aparecida de Oliveira Tiera, Vera, José Tiera, Marcio

“…In recent years, the therapeutic potential of small interfering RNA (siRNA) has been confirmed by the emergence of commercially available siRNA-based drugs and…”
Get full text

Amphipathic chitosans improve the physicochemical properties of siRNA-chitosan nanoparticles at physiological conditions by Martins, Grazieli Olinda, Segalla Petrônio, Maicon, Furuyama Lima, Aline Margarete, Martinez Junior, André Miguel, de Oliveira Tiera, Vera Aparecida, de Freitas Calmon, Marília, Leite Vilamaior, Patricia Simone, Han, Sang Won, Tiera, Marcio José

“…[Display omitted] •Chitosan derivatives were synthesized and characterized.•Amphipathic character is tuned by degree of acetylation and tertiary amino…”
Get full text

In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice by Shi, Qin, Rondon-Cavanzo, Elsa-Patricia, Dalla Picola, Isadora Pfeifer, Tiera, Marcio José, Zhang, Xiaoling, Dai, Kerong, Benabdoune, Houda Abir, Benderdour, Mohamed, Fernandes, Julio Cesar

“…Tumor necrosis factor-alpha (TNFα), a pro-inflammatory cytokine, has been shown to play a role in the pathophysiology of rheumatoid arthritis. Silencing TNFα…”
Get full text

Amphiphilic diethylaminoethyl chitosan of high molecular weight as an edible film by da Mata Cunha, Otávio, Lima, Aline Margarete Furuyama, Assis, Odílio Benedito Garrido, Tiera, Márcio José, de Oliveira Tiera, Vera Aparecida

“…Edible films and coatings can enhance the quality of food products, protecting them from biological deterioration, especially against fungal diseases and…”
Get full text

Self-assembly in aqueous solution of amphiphilic graft copolymers from oxidized carboxymethylcellulose by Bordallo, Eduardo, Rieumont, Jacques, Tiera, Marcio José, Gómez, Manuel, Lazzari, Massimo

“…•OCMC-g-PEG-DDA copolymers synthesis.•Micelles characterization by different techniques.•Dependence of micelles properties on the PEG/DDA ratio. A series of…”
Get full text

Evidence Supporting the Safety of Pegylated Diethylaminoethyl-Chitosan Polymer as a Nanovector for Gene Therapy Applications by Rondon, Elsa Patricia, Benabdoun, Houda Abir, Vallières, Francis, Segalla Petrônio, Maicon, Tiera, Marcio José, Benderdour, Mohamed, Fernandes, Julio Cesar

“…Diethylaminoethyl-chitosan (DEAE-CH) is a derivative with excellent potential as a delivery vector for gene therapy applications. The aim of this study is to…”
Get full text

Chitosan derivatives targeting lipid bilayers: Synthesis, biological activity and interaction with model membranes by Martins, Danubia Batista, Nasário, Fábio Domingues, Silva-Gonçalves, Laiz Costa, de Oliveira Tiera, Vera Aparecida, Arcisio-Miranda, Manoel, Tiera, Marcio José, dos Santos Cabrera, Marcia Perez

“…•Hydrophobic and cationic low MW chitosans exhibit increased antimicrobial activity in relation to the intermediate and starting compounds.•Derivative with…”
Get full text

Diethylaminoethyl- chitosan as an efficient carrier for siRNA delivery: Improving the condensation process and the nanoparticles properties by de Souza, Ricchard Hallan Felix Viegas, Picola, Isadora Pfeifer Dalla, Shi, Qin, Petrônio, Maicon Segalla, Benderdour, Mohamed, Fernandes, Júlio Cesar, Lima, Aline Margarete Furuyama, Martins, Grazieli Olinda, Martinez Junior, André Miguel, de Oliveira Tiera, Vera Aparecida, Tiera, Marcio José

“…Chitosan has been indicated as a promising carrier for the preparation of small interfering RNA (siRNA) delivery systems due to its remarkable properties…”
Get full text

Insights on the antifungal activity of amphiphilic derivatives of diethylaminoethyl chitosan against Aspergillus flavus by Dias, Amanda Manchini, dos Santos Cabrera, Marcia Perez, Lima, Aline Margarete Furuyama, Taboga, Sebastião Roberto, Vilamaior, Patricia Simone Leite, Tiera, Marcio José, de Oliveira Tiera, Vera Aparecida

“…[Display omitted] •A. flavus growth inhibition by chitosan derivatives require marked hydrophobicity.•Controlled amphiphilicity and low Mw determine the most…”
Get full text

Effect of ionic strength solution on the stability of chitosan-DNA nanoparticles by Picola, Isadora Pfeifer Dalla, Busson, Karen Andressa Nunes, Casé, Ana Helena, Nasário, Fábio Domingues, Tiera, Vera Aparecida de Oliveira, Taboga, Sebastião Roberto, Neto, João Ruggiero, Tiera, Marcio José

“…Chitosan-DNA nanoparticles employed in gene therapy protocols consist of a neutralised, stoichiometric core and a shell of the excess of chitosan which…”
Get full text

Thermodynamics of the aggregation of imidazolium ionic liquids with sodium alginate or hydroxamic alginate in aqueous solution by de Freitas, Darcson Vieira, Kuhn, Bruna Luiza, Bender, Caroline Raquel, Furuyama Lima, Aline Margarete, de Freitas Lima, Marcelo, Tiera, Marcio José, Kloster, Carmen Luisa, Frizzo, Clarissa Piccinin, Villetti, Marcos Antonio

“…Ionic liquids (ILs) were examined as new components in polymer/IL mixtures for their potential applications as advanced materials. This work reports the…”
Get full text