Search Results - "Tiemessen, M."

Surprising impact of stromal TIL’s on immunotherapy efficacy in a real-world lung cancer study by Hashemi, S., Fransen, M.F., Niemeijer, A., Ben Taleb, N., Houda, I., Veltman, J., Becker- Commissaris, A., Daniels, H., Crombag, L., Radonic, T., Jongeneel, G., Tarasevych, S., Looysen, E., van Laren, M., Tiemessen, M., van Diepen, V., Maassen-van den Brink, K., Thunnissen, E., Bahce, I.

“…•Real world datasets are needed to assess biomarker performances in daily routine practice.•The stromal CD8+TILs were found to be the strongest predictor for…”
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CD4⁺CD25⁺Foxp3⁺ regulatory T cells induce alternative activation of human monocytes/macrophages by Tiemessen, Machteld M, Jagger, Ann L, Evans, Hayley G, van Herwijnen, Martijn J.C, John, Susan, Taams, Leonie S

“…CD4⁺CD25⁺Foxp3⁺ regulatory T cells (Tregs) are potent suppressors of the adaptive immune system, but their effects on innate immune cells are less well known…”
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Management of Cow's Milk Allergy from an Immunological Perspective: What Are the Options? by Knol, Edward F, de Jong, Nicolette W, Ulfman, Laurien H, Tiemessen, Machteld M

“…The immunological mechanism underlying Immunoglobuline E (IgE)-mediated cow's milk allergy has been subject to investigations for many years. Identification of…”
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Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges by Bolhaar, S. T. H. P., Tiemessen, M. M., Zuidmeer, L., Van Leeuwen, A., Hoffmann-Sommergruber, K., Bruijnzeel-Koomen, C. A. F. M., Taams, L. S., Knol, E. F., Van Hoffen, E., Van Ree, R., Knulst, A. C.

“…Summary Background The effect of birch‐pollen immunotherapy (IT) on cross‐reactive food allergies is controversial. Objective The aim of this study was to…”
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Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels by Tiemessen, Machteld M, Solforosi, Laura, Dekking, Liesbeth, Czapska-Casey, Dominika, Serroyen, Jan, Sullivan, Nancy J, Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Schuitemaker, Hanneke, Luhn, Kerstin, Zahn, Roland, Roozendaal, Ramon

“…The Marburg virus (MARV) and Sudan virus (SUDV) belong to the filovirus family. The sporadic human outbreaks occur mostly in Africa and are characterized by an…”
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Decreased Histone Acetylation Levels at Th1 and Regulatory Loci after Induction of Food Allergy by Alashkar Alhamwe, Bilal, Meulenbroek, Laura A P M, Veening-Griffioen, Désirée H, Wehkamp, Tjalling M D, Alhamdan, Fahd, Miethe, Sarah, Harb, Hani, Hogenkamp, Astrid, Knippels, Léon M J, Pogge von Strandmann, Elke, Renz, Harald, Garssen, Johan, van Esch, Betty C A M, Garn, Holger, Potaczek, Daniel P, Tiemessen, Machteld M

“…Immunoglobulin E (IgE)-mediated allergy against cow's milk protein fractions such as whey is one of the most common food-related allergic disorders of early…”
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Real-Time Access to Electronic Health Record via a Patient Portal in a Tertiary Hospital: Is it Harmful? A Retrospective Mixed Methods Observational Study by van Kuppenveld, Savannah IR, van Os-Medendorp, Harmieke, Tiemessen, Nicole AM, van Delden, Johannes JM

“…Background: The rapid implementation of patient portals, through which patients can view their electronic health record, creates possibilities for information…”
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The poly(I:C)-induced maternal immune activation model; a systematic review and meta-analysis of cytokine levels in the offspring by Hameete, Bart C., Fernández-Calleja, José M.S., de Groot, Martje W.G.D.M., Oppewal, Titia Rixt, Tiemessen, Machteld M., Hogenkamp, Astrid, de Vries, Rob B.M., Groenink, Lucianne

“…The maternal polyinosinic:polycytidylic acid (poly(I:C)) animal model is frequently used to study how maternal immune activation may impact neuro development…”
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Discrete roles of canonical and non-canonical Wnt signaling in hematopoiesis and lymphopoiesis by Famili, F, Naber, B A E, Vloemans, S, de Haas, E F E, Tiemessen, M M, Staal, F J T

“…The mechanisms that regulate proliferation, fate decisions and differentiation of hematopoietic stem cells (HSC) and thymic stem cells are highly complex…”
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Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells by Taams, Leonie S., van Amelsfort, Jocea M.R., Tiemessen, Machteld M., Jacobs, Kim M.G., de Jong, Esther C., Akbar, Arne N., Bijlsma, Johannes W.J., Lafeber, Floris P.J.G.

“…The suppressive effects of CD4+CD25+ regulatory T cells (Tregs) on T cells have been well documented. Here we investigated whether human CD4+CD25+ Tregs can…”
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The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas by Tiemessen, Machteld M, Baert, Miranda R M, Schonewille, Tom, Brugman, Martijn H, Famili, Farbod, Salvatori, Daniela C F, Meijerink, Jules P P, Ozbek, Ugur, Clevers, Hans, van Dongen, Jacques J M, Staal, Frank J T

“…The HMG-box factor Tcf1 is required during T-cell development in the thymus and mediates the nuclear response to Wnt signals. Tcf1(-/-) mice have previously…”
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Urethral reconstruction of critical defects in rabbits using molecularly defined tubular type I collagen biomatrices: key issues in growth factor addition by Nuininga, Jody E, Koens, Martin J W, Tiemessen, Dorien M, Oosterwijk, Egbert, Daamen, Willeke F, Geutjes, Paul J, van Kuppevelt, Toin H, Feitz, Wout F J

“…Tubular type I collagen biomatrices with and without growth factors (GFs) were constructed and evaluated in a rabbit model for critical urethral defects…”
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Tissue engineering of diseased bladder using a collagen scaffold in a bladder exstrophy model by Roelofs, Luc A.J., Kortmann, Barbara B.M., Oosterwijk, Egbert, Eggink, Alex J., Tiemessen, Dorien M., Crevels, A. Jane, Wijnen, Rene M.H., Daamen, Willeke F., Kuppevelt, Toin H., Geutjes, Paul J., Feitz, Wout F.J.

“…Objective To compare the regenerative capacity of diseased bladder in a large animal model of bladder exstrophy with regeneration in healthy bladder using a…”
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Cow's milk–specific T-cell reactivity of children with and without persistent cow's milk allergy: Key role for IL-10 by Tiemessen, Machteld M., Van Ieperen-Van Dijk, Adrie G., Bruijnzeel-Koomen, Carla A.F.M., Garssen, Johan, Knol, Edward F., Van Hoffen, Els

“…The role of antigen-specific T cells in the mechanism of food allergy or maintenance of tolerance toward an innocuous antigen, such as cow's milk, is not yet…”
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Use and the Users of a Patient Portal: Cross-Sectional Study by Hoogenbosch, Bas, Postma, Jeroen, de Man-van Ginkel, Janneke M, Tiemessen, Nicole Am, van Delden, Johannes Jm, van Os-Medendorp, Harmieke

“…Patient portals offer patients access to their medical information and tools to communicate with health care providers. It has been shown that patient portals…”
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Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti‐inflammatory macrophages by Melief, Sara M., Schrama, Ellen, Brugman, Martijn H., Tiemessen, Machteld M., Hoogduijn, Martin J., Fibbe, Willem E., Roelofs, Helene

“…ABSTRACT Multipotent stromal cells (MSC) have been shown to possess immunomodulatory capacities and are therefore explored as a novel cellular therapy. One of…”
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The role of monocytes in the immunoregulatory function of multipotent stromal cells by Melief, S, Schrama, E, Geutskens, S, Tiemessen, M, Brugman, M, Fibbe, W, Roelofs, H

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Risk factors for hypoglycaemia in neurocritical care patients by van Iersel, Freya M., Slooter, Arjen J. C., Vroegop, Renee, Wolters, Annemiek E., Tiemessen, Charlotte A. M., Rösken, Rik H. J., van der Hoeven, Johannes G., Peelen, Linda M., Hoedemaekers, Cornelia W. E.

“…Purpose To identify risk factors for hypoglycaemia in neurocritical care patients receiving intensive insulin therapy (IIT). Methods We performed a nested…”
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WNT signalling in the immune system: WNT is spreading its wings by Staal, Frank J. T, Luis, Tiago C, Tiemessen, Machteld M

“…Key Points There are different WNT signalling pathways: the canonical WNT pathway, which involves β-catenin and members of the T-cell factor…”
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Interleukin, tumor necrosis factor-α and C-reactive protein profiles in melancholic and non-melancholic depression: A systematic review by Yang, Chenghao, Tiemessen, Kim M., Bosker, Fokko J., Wardenaar, Klaas J., Lie, Jie, Schoevers, Robert A.

“…The current diagnostic criteria for major depressive disorder (MDD) do not allow prediction of prognosis and therapeutic response. A possible strategy to…”
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